Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications

Diabetic Retinopathy

1974 • 5,744 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Tumor necrosis factor and interleukin 1: cytokines with multiple overlapping biological activities.

1987 • 1,345 citations

Aminoguanidine Prevents Diabetes-Induced Arterial Wall Protein Cross-Linking

1986 • 1,154 citations

Nonenzymatic Glycosylation and the Pathogenesis of Diabetic Complications

1984 • 1,012 citations

Sorbitol, Phosphoinositides, and Sodium-Potassium-ATPase in the Pathogenesis of Diabetic Complications

1987 • 905 citations

The case for intrarenal hypertension in the initiation and progression of diabetic and other glomerulopathies

1982 • 807 citations

[2] Preparation and characterization of the different types of collagen

1982 • 758 citations

Nonenzymatic Browning in Vivo: Possible Process for Aging of Long-Lived Proteins

1981 • 754 citations

Accelerated age-related browning of human collagen in diabetes mellitus.

1984 • 671 citations

Relation between Complications of Type I Diabetes Mellitus and Collagen-Linked Fluorescence

1986 • 579 citations

Predominance of hemodynamic rather than metabolic factors in the pathogenesis of diabetic glomerulopathy.

1985 • 532 citations

Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta.

1985 • 436 citations

The Biochemistry of the Complications of Diabetes Mellitus

1981 • 430 citations

Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers.

1986 • 401 citations

Pathogenesis of Diabetic Retinopathy

1989 • 325 citations

High-affinity-receptor-mediated uptake and degradation of glucose-modified proteins: a potential mechanism for the removal of senescent macromolecules.

1985 • 312 citations

Banting Lecture 1986: Does a Common Mechanism Induce the Diverse Complications of Diabetes?

1987 • 275 citations

Demonstration of vasoproliferative activity from mammalian retina.

1980 • 272 citations

Long term correction of hyperglycaemia and progression of renal failure in insulin dependent diabetes

1983 • 257 citations

Glucose and Aging

1987 • 244 citations

[1] Collagen: An overview

1982 • 241 citations

Thrombin stimulates c-sis gene expression in microvascular endothelial cells.

1986 • 235 citations

Nonenzymatic glucosylation and glucose-dependent cross-linking of protein.

1983 • 218 citations

Studies on Macromolecular Components of Human Glomerular Basement Membrane and Alterations in Diabetes: Decreased Levels of Heparan Sulfate Proteoglycan and Laminin

1987 • 208 citations

Nonenzymatic Glycosylation Products on Collagen Covalently Trap Low-Density Lipoprotein

1985 • 203 citations

Models for the self-assembly of basement membrane.

1986 • 172 citations

Evidence for glucose-mediated covalent cross-linking of collagen after glycosylation in vitro

1985 • 164 citations

Covalent attachment of soluble proteins by nonenzymatically glycosylated collagen. Role in the in situ formation of immune complexes.

1983 • 157 citations

Novel macrophage receptor for glucose-modified proteins is distinct from previously described scavenger receptors.

1986 • 156 citations

Glycation of Skin Collagen in Type I Diabetes Mellitus: Correlation With Long-Term Complications

1986 • 121 citations

Permeability and patency of retinal blood vessels in experimental diabetes.

1977 • 103 citations

Studies on macromolecular components of human glomerular basement membrane and alterations in diabetes. Decreased levels of heparan sulfate proteoglycan and laminin

1987 • 88 citations

Functional and morphological renal manifestations in diabetes mellitus

1981 • 82 citations

Nonenzymatic glycosylation products on collagen covalently trap low-density lipoprotein

1985 • 77 citations

Advanced Diabetic Glomerulopathy: Quantitative Structural Characterization of Nonoccluded Glomeruli

1987 • 77 citations

Introduction: Diabetes mellitus and the kidney

1982 • 76 citations

Evidence for functional endothelial cell damage in early diabetic retinopathy

1981 • 70 citations

Specific Macrophage Receptor Activity for Advanced Glycosylation End Products Inversely Correlates With Insulin Levels In Vivo

1988 • 68 citations

Functional Nature of Glomerular Injury in Progressive Diabetic Glomerulopathy

1987 • 60 citations

Glomerular Proteoglycans in Diabetes: Partial Structural Characterization and Metabolism of De Novo Synthesized Heparan-35SO4 and Dermatan-35SO4 Proteoglycans in Streptozocin-Induced Diabetic Rats

1986 • 51 citations

Glycation of skin collagen in type I diabetes mellitus. Correlation with long-term complications

1986 • 38 citations

Diabetic nephropathy in the uninephrectomized dog: Microscopic lesions after one year

1982 • 37 citations

Diabetic Nephropathy: A Perspective

1983 • 35 citations

Advanced diabetic glomerulopathy. Quantitative structural characterization of nonoccluded glomeruli

1987 • 30 citations

Specific macrophage receptor activity for advanced glycosylation end products inversely correlates with insulin levels in vivo

1988 • 29 citations

Non enzymatic glycosylation increases platelet aggregating potency of collagen from placenta of diabetic human beings

1983 • 27 citations

In vivo influx of free and esterified plasma cholesterol into human aortic tissue without atherosclerotic lesions.

1984 • 27 citations

Functional nature of glomerular injury in progressive diabetic glomerulopathy

1987 • 24 citations

The biochemistry of the complications of diabetes mellitus

1982 • 23 citations

Trapped immunoglobulins on peripheral nerve myelin from patients with diabetes mellitus

1986 • 20 citations

Glomerular proteoglycans in diabetes. Partial structural characterization and metabolism of de novo synthesized heparan-35SO4 and dermatan-35SO4 proteoglycans in streptozocin-induced diabetic rats

1986 • 15 citations

Human Glomerular Basement Membrane: Altered Binding Characteristics following in Vitro Non-enzymatic Glycosylation

1986 • 10 citations

Human Glomerular Basement Membrane: Altered Binding Characteristics following in Vitro Non-enzymatic Glycosylation

1986 • 7 citations