Increased KGF Expression Promotes Fibroblast Activation in a Double Paracrine Manner Resulting in Cutaneous Fibrosis

Regulation of Wound Healing by Growth Factors and Cytokines

2003 • 3,383 citations

Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

2007 • 1,380 citations

Keratinocyte–Fibroblast Interactions in Wound Healing

2007 • 1,165 citations

Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.

1992 • 760 citations

Stat3 regulates genes common to both wound healing and cancer

2005 • 371 citations

Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder

2001 • 356 citations

Keratinocyte growth regulation in fibroblast cocultures via a double paracrine mechanism

1999 • 288 citations

Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice.

1993 • 263 citations

A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy

2010 • 239 citations

gp130 at the nexus of inflammation, autoimmunity, and cancer

2010 • 235 citations

Keloids: Current concepts of pathogenesis (Review)

2009 • 218 citations

Human keratinocyte growth factor effects in a porcine model of epidermal wound healing.

1993 • 200 citations

Mechanisms and consequences of fibrosis in systemic sclerosis

2006 • 175 citations

Fibroblasts from the growing margin of keloid scars produce higher levels of collagen I and III compared with intralesional and extralesional sites: clinical implications for lesional site-directed therapy

2010 • 156 citations

Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions

2007 • 146 citations

Keratinocyte Growth Factor-2 Accelerates Wound Healing in Incisional Wounds

1999 • 134 citations

Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) Attenuates Interleukin-6 (IL-6)-induced Collagen Synthesis and Resultant Hypertrophy in Rat Heart

2011 • 130 citations

Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis

2008 • 128 citations

Expression and Function of Keratinocyte Growth Factor and Activin in Skin Morphogenesis and Cutaneous Wound Repair

2000 • 121 citations

Epithelial Cells Promote Fibroblast Activation via IL-1α in Systemic Sclerosis

2010 • 119 citations

Green Tea Polyphenol Epigallocatechin-3-Gallate Suppresses Collagen Production and Proliferation in Keloid Fibroblasts via Inhibition of the STAT3-Signaling Pathway

2008 • 118 citations

Stat3 contributes to keloid pathogenesis via promoting collagen production, cell proliferation and migration

2006 • 117 citations

STAT3-Mediated Signaling Dysregulates Lung Fibroblast-Myofibroblast Activation and Differentiation in UIP/IPF

2012 • 115 citations

Keratinocyte Growth Factor/Fibroblast Growth Factor-7-regulated Cell Migration and Invasion through Activation of NF-κB Transcription Factors

2007 • 97 citations

Oncostatin M stimulates proliferation, induces collagen production and inhibits apoptosis of human lung fibroblasts

2002 • 92 citations

Hypertrophic scars and keloids: a review and new concept concerning their origin.

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Fibroproliferative Disorders and Their Mechanobiology

2012 • 87 citations

Cytokine Profiling and Stat3 Phosphorylation in Epithelial–Mesenchymal Interactions between Keloid Keratinocytes and Fibroblasts

2008 • 77 citations

Interleukin-6-Type Cytokines Upregulate Expression of Multidrug Resistance-Associated Proteins in NHEK and Dermal Fibroblasts

2005 • 76 citations

Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option

2010 • 68 citations

CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration

2011 • 67 citations

Genetics of Systemic Sclerosis: An Update

2011 • 64 citations

Decreased Expression of Fibroblast and Keratinocyte Growth Factor Isoforms and Receptors during Scarless Repair

2003 • 61 citations

Comparative proteomic analysis between normal skin and keloid scar

2010 • 60 citations

The genetics of systemic sclerosis: an update.

2011 • 49 citations

Use of organotypic coculture to study keloid biology

2008 • 47 citations

Differences in collagen production between normal and keloid-derived fibroblasts in serum-media co-culture with keloid-derived keratinocytes

2002 • 45 citations

Lipoprotein Receptor–Related Protein 1 Regulates Collagen 1 Expression, Proteolysis, and Migration in Human Pleural Mesothelial Cells

2011 • 27 citations

Treatment of morphea or localized scleroderma: review of the literature.

2010 • 23 citations

Induction of the urokinase plasminogen activator system by oncostatin M promotes endothelial migration

2000 • 20 citations

The Plasminogen Activator System in Fibroblasts from Systemic Sclerosis

2010 • 17 citations

Expression of Urokinase-type Plasminogen Activator and Its Receptor in Keloids

2003 • 14 citations

An in vitro analysis of mechanical wounding-induced ligand-independent KGFR activation

2008 • 14 citations