Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

How does the extracellular matrix direct gene expression?

1982 • 1,475 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

Human KGF is FGF-Related with Properties of a Paracrine Effector of Epithelial Cell Growth

1989 • 989 citations

Production and auto-induction of transforming growth factor-α in human keratinocytes

1987 • 870 citations

Purification and characterization of a newly identified growth factor specific for epithelial cells.

1989 • 842 citations

Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.

1992 • 760 citations

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1990 • 753 citations

Cell migration is essential for sustained growth of keratinocyte colonies: The roles of transforming growth factor-α and epidermal growth factor

1987 • 703 citations

Induction of hair growth by implantation of cultured dermal papilla cells

1984 • 623 citations

Large induction of keratinocyte growth factor expression in the dermis during wound healing.

1992 • 603 citations

Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes.

1984 • 567 citations

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse

1992 • 552 citations

Competitive PCR

1992 • 528 citations

Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells.

1983 • 484 citations

Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation.

1991 • 407 citations

Developmental expression of two murine fibroblast growth factor receptors, fig and bek

1991 • 397 citations

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice.

1989 • 365 citations

Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.

1988 • 359 citations

The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies.

1983 • 355 citations

Expression of epidermal keratins and filaggrin during human fetal skin development.

1985 • 284 citations

Epidermal growth factor-like transforming growth factor. I. Isolation, chemical characterization, and potentiation by other transforming factors from feline sarcoma virus-transformed rat cells.

1983 • 266 citations

Human keratinocyte growth factor activity on proliferation and differentiation of human keratinocytes: Differentiation response distinguishes KGF from EGF family

1990 • 228 citations

Epimorphin: A mesenchymal protein essential for epithelial morphogenesis

1992 • 222 citations

Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation.

1989 • 196 citations

Characterization of the receptor for keratinocyte growth factor. Evidence for multiple fibroblast growth factor receptors.

1990 • 187 citations

A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin.

1989 • 155 citations

Keratinocyte Growth Factor: A Fibroblast Growth Factor Family Member with Unusual Target Cell Specificity

1991 • 153 citations

Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice.

1992 • 150 citations

Antibodies to cell surface ganglioside GD3 perturb inductive epithelial-mesenchymal interactions

1988 • 142 citations

TGF-beta and retinoic acid: regulators of growth and modifiers of differentiation in human epidermal cells.

1990 • 129 citations

The development of mouse vibrissae in vivo and in vitro.

1952 • 125 citations

Distribution and number of epidermal growth factor receptors in skin is related to epithelial cell growth

1983 • 124 citations

Nonproliferation in dermal condensations of mouse vibrissae and pelage hairs

1965 • 122 citations

Distribution of Epidermal Growth Factor Receptors in Rat Tissues During Embryonic Skin Development, Hair Formation, and the Adult Hair Growth Cycle

1984 • 113 citations

Transgenic overexpression of transforming growth factor alpha bypasses the need for c-Ha-ras mutations in mouse skin tumorigenesis.

1992 • 107 citations

The specification of feather and scale protein synthesis in epidermal-dermal recombinations

1978 • 104 citations

Characterization of cytoskeletal proteins in basal cells of human parotid salivary gland ducts

1988 • 79 citations

Sequence and expression of a type II keratin, K5, in human epidermal cells.

1988 • 74 citations

Evaluation of the cocarcinogenic effect of wounding in Rous sarcoma virus tumorigenesis.

1989 • 57 citations

Transforming growth factor alpha induces collagen degradation and cell migration in differentiating human epidermal raft cultures.

1991 • 46 citations

Localization of Profilaggrin mRNA in Newborn Rat Skin by In Situ Hybridization

1987 • 45 citations

Basal Lamina Changes During Tissue Interactions in Hair Follicles—An In Vitro Study of Normal Dermal Papillae and Vitamin A-Induced Glandular Morphogenesis

1983 • 34 citations

Sequence and Expression of a Type II Keratin, K5, in Human Epidermal Cells

1988 • 17 citations

Transgenic Overexpression of Transforming Growth Factor α Bypasses the Need for c-Ha-ras Mutations in Mouse Skin Tumorigenesis

1992 • 16 citations

Development of hair coat and skin glands in fetal porcine integument.

1986 • 15 citations