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Comparative proteomic analysis between normal skin and keloid scar

Data up to Jan 2025

Published2010
Citations60
References74

Total Citations Per Year

Abstract

References (74)

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1993 • 2,169 citations

Transforming growth factor beta

2011 • 1,990 citations

Pigment Epithelium-Derived Factor: A Potent Inhibitor of Angiogenesis

1999 • 1,494 citations

Linking genome and proteome by mass spectrometry: Large-scale identification of yeast proteins from two dimensional gels

1996 • 1,430 citations

p63 identifies keratinocyte stem cells

2001 • 1,339 citations

Is a p53-Regulated Inhibitor of G2/M Progression

1997 • 1,238 citations

Apoptosis of T cells mediated by galectin-1

1995 • 1,056 citations

On the Nature of Hypertrophic Scars and Keloids: A Review

1999 • 785 citations

Regulation ofp53downstream genes

1998 • 777 citations

The molecular and cellular biology of wound repair

1996 • 562 citations

An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis

2005 • 454 citations

Recombinant Galectin-1 and Its Genetic Delivery Suppress Collagen-Induced Arthritis via T Cell Apoptosis

1999 • 358 citations

PEDF: a multifaceted neurotrophic factor

2003 • 349 citations

Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor

2003 • 311 citations

Molecular Cloning and Expression of a Novel Keratinocyte Protein (Psoriasis-associated fatty acid-binding protein [PA-FABP]) that Is Highly Up-Regulated in Psoriatic Skin and that Shares Similarity to Fatty Acid-Binding Proteins

1992 • 257 citations

Galectin-1 suppresses experimental colitis in mice

2003 • 253 citations

Activation of Collagen Gene Expression in Keloids: Co-Localization of Type I and VI Collagen and Transforming Growth Factor-β1 mRNA

1991 • 250 citations

The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor

2001 • 242 citations

Expression of Transforming Growth Factor Beta 1, 2, and 3 Proteins in Keloids

1999 • 233 citations

Downregulation of 14-3-3σ Prevents Clonal Evolution and Leads to Immortalization of Primary Human Keratinocytes

2000 • 228 citations

Gene expression profiling of cutaneous wound healing

2007 • 218 citations

Specific inhibition of T‐cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin‐1

1999 • 207 citations

Galectin-1 Induces Partial TCR ζ-Chain Phosphorylation and Antagonizes Processive TCR Signal Transduction

2000 • 207 citations

Presentation of Galectin-1 by Extracellular Matrix Triggers T Cell Death

2004 • 191 citations

Modulation of Collagen Synthesis by Transforming Growth Factor-β in Keloid and Hypertrophic Scar Fibroblasts

1994 • 189 citations

Activated Rat Macrophages Produce a Galectin-1-Like Protein That Induces Apoptosis of T Cells: Biochemical and Functional Characterization

1998 • 178 citations

The Differentiation and Function of Myofibroblasts is Regulated by Mast Cell Mediators

2001 • 172 citations

Alpha 1-proteinase inhibitor is a neutrophil chemoattractant after proteolytic inactivation by macrophage elastase.

1988 • 170 citations

Modulation of Cell Proliferation by Cytokeratins K10 and K16

1999 • 170 citations

Pigment epithelium-derived factor (PEDF) in neuroblastoma: a multifunctional mediator of Schwann cell antitumor activity

2001 • 168 citations

Expression of Transforming Growth Factor Beta 1, 2, and 3 Proteins in Keloids

1999 • 159 citations

Functional Implications of the IL-6 Signaling Pathway in Keloid Pathogenesis

2006 • 157 citations

The human keratinocyte two‐dimensional gel protein database (update 1992): Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

1992 • 125 citations

Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1α and vascular endothelial growth factor

2005 • 125 citations

Measurement of plasma calprotectin as an indicator of arthritis and disease activity in patients with inflammatory rheumatic diseases.

1994 • 122 citations

Keratinocyte-Releasable Stratifin Functions as a Potent Collagenase-Stimulating Factor in Fibroblasts

2004 • 121 citations

The human keratinocyte two‐dimensional gel protein database (update 1995): Mapping components of signal transduction pathways

1995 • 115 citations

α1-Antitrypsin Is Degraded and Non-Functional in Chronic Wounds But Intact and Functional in Acute Wounds: The Inhibitor Protects Fibronectin from Degradation by Chronic Wound Fluid Enzymes

1995 • 112 citations

Macrophage Migration Inhibitory Factor

2005 • 105 citations

Increased Proliferation in Keloid Fibroblasts Woundedin Vitro

1996 • 102 citations

Green Tea Extract and (−)-Epigallocatechin-3-Gallate Inhibit Mast Cell-Stimulated Type I Collagen Expression in Keloid Fibroblasts via Blocking PI-3K/Akt Signaling Pathways

2006 • 101 citations

Complex pattern of the myelo-monocytic differentiation antigens MRP8 and MRP14 during chronic airway inflammation

1992 • 96 citations

Analysis of differentially expressed genes in keloids and normal skin with cDNA microarray

2003 • 96 citations

A Partial Catalog of Proteins Secreted by Epidermal Keratinocytes in Culture

1999 • 95 citations

Dimeric galectin‐1 induces IL‐10 production in T‐lymphocytes: an important tool in the regulation of the immune response

2004 • 94 citations

Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)‐β1–induced collagen synthesis

2007 • 88 citations

Gene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage

2005 • 88 citations

Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte‐fibroblast coculture contributes to keloid pathogenesis

2006 • 88 citations

Proliferating activity of dermal fibroblasts in keloids and hypertrophic scars.

1995 • 88 citations

Galectin-1 and Galectin-3 in Chronic Pancreatitis

2000 • 86 citations

TISSUE ALPHA-GLOBULINS IN KELOID FORMATION

1977 • 82 citations

Calgranulin expression in inflammatory dermatoses

1989 • 80 citations

A Proteomic Characterization of the Plasma Membrane of Human Epidermis by High-Throughput Mass Spectrometry

2004 • 79 citations

Collagen Biosynthesis in Normal Human Skin, Normal and Hypertrophic Scar and Keloid

1975 • 74 citations

Activation of NF?B signal pathways in keloid fibroblasts

2004 • 72 citations

Epithelial–mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion

2006 • 70 citations

Tumor Suppressor Maspin Is Up-Regulated during Keratinocyte Senescence, Exerting a Paracrine Antiangiogenic Activity

2004 • 67 citations

Gene expression patterns in isolated keloid fibroblasts

2006 • 65 citations

Comparative Proteomic Profiling of Murine Skin

2003 • 61 citations

The role of the activin system in keloid pathogenesis

2006 • 59 citations

Manganese Superoxide Dismutase Protects the Proliferative Capacity of Confluent Normal Human Fibroblasts

2005 • 57 citations

Hyaluronic acid metabolism in keloid fibroblasts

1995 • 55 citations

The human keratinocyte two‐dimensional protein database (update 1994): Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

1994 • 54 citations

Increased Fibronectin Production by Cell Lines from Hypertrophic Scar and Keloid

1989 • 53 citations

Protein Profiling of the Human Epidermis from the Elderly Reveals Up-regulation of a Signature of Interferon-γ-induced Polypeptides That Includes Manganese-superoxide Dismutase and the p85β Subunit of Phosphatidylinositol 3-Kinase

2003 • 41 citations

Epidermal expression of the calcium binding surface antigen 27E10 in inflammatory skin diseases

1992 • 40 citations

Immunohistochemical localization of carbonic anhydrase I and II in eccrine sweat glands from control subjects and patients with cystic fibrosis.

1983 • 38 citations

A Controversial Tumor Marker: Is SM22 a Proper Biomarker for Gastric Cancer Cells?

2007 • 37 citations

Decreased Prostaglandin E2 Production by Inflammatory Cytokine and Lower Expression of EP2 Receptor Result in Increased Collagen Synthesis in Keloid Fibroblasts

2006 • 29 citations

Effects of density and cellular aging on collagen synthesis and growth kinetics in keloid and normal skin fibroblasts

1982 • 26 citations

Normal human dermal fibroblasts: Proteomic analysis of cell layer and culture medium

2003 • 24 citations

Immunohistochemical study of carbonic anhydrase isozymes in human skin.

2003 • 12 citations

[Inflammatory rheumatic diseases].

2009 • 5 citations

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Comparative proteomic analysis between normal skin and keloid scar (2010) – British Journal of Dermatology | Metascience Observatory Explorer