Comparative proteomic analysis between normal skin and keloid scar
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References (74)
The Transforming Growth Factor-beta Family
1990 • 3,028 citations
Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
1993 • 2,169 citations
Transforming growth factor beta
2011 • 1,990 citations
Pigment Epithelium-Derived Factor: A Potent Inhibitor of Angiogenesis
1999 • 1,494 citations
Linking genome and proteome by mass spectrometry: Large-scale identification of yeast proteins from two dimensional gels
1996 • 1,430 citations
p63 identifies keratinocyte stem cells
2001 • 1,339 citations
Is a p53-Regulated Inhibitor of G2/M Progression
1997 • 1,238 citations
Apoptosis of T cells mediated by galectin-1
1995 • 1,056 citations
On the Nature of Hypertrophic Scars and Keloids: A Review
1999 • 785 citations
Regulation ofp53downstream genes
1998 • 777 citations
The molecular and cellular biology of wound repair
1996 • 562 citations
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis
2005 • 454 citations
Recombinant Galectin-1 and Its Genetic Delivery Suppress Collagen-Induced Arthritis via T Cell Apoptosis
1999 • 358 citations
PEDF: a multifaceted neurotrophic factor
2003 • 349 citations
Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor
2003 • 311 citations
Molecular Cloning and Expression of a Novel Keratinocyte Protein (Psoriasis-associated fatty acid-binding protein [PA-FABP]) that Is Highly Up-Regulated in Psoriatic Skin and that Shares Similarity to Fatty Acid-Binding Proteins
1992 • 257 citations
Galectin-1 suppresses experimental colitis in mice
2003 • 253 citations
Activation of Collagen Gene Expression in Keloids: Co-Localization of Type I and VI Collagen and Transforming Growth Factor-β1 mRNA
1991 • 250 citations
The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor
2001 • 242 citations
Expression of Transforming Growth Factor Beta 1, 2, and 3 Proteins in Keloids
1999 • 233 citations
Downregulation of 14-3-3σ Prevents Clonal Evolution and Leads to Immortalization of Primary Human Keratinocytes
2000 • 228 citations
Gene expression profiling of cutaneous wound healing
2007 • 218 citations
Specific inhibition of T‐cell adhesion to extracellular matrix and proinflammatory cytokine secretion by human recombinant galectin‐1
1999 • 207 citations
Galectin-1 Induces Partial TCR ζ-Chain Phosphorylation and Antagonizes Processive TCR Signal Transduction
2000 • 207 citations
Presentation of Galectin-1 by Extracellular Matrix Triggers T Cell Death
2004 • 191 citations
Modulation of Collagen Synthesis by Transforming Growth Factor-β in Keloid and Hypertrophic Scar Fibroblasts
1994 • 189 citations
Activated Rat Macrophages Produce a Galectin-1-Like Protein That Induces Apoptosis of T Cells: Biochemical and Functional Characterization
1998 • 178 citations
The Differentiation and Function of Myofibroblasts is Regulated by Mast Cell Mediators
2001 • 172 citations
Alpha 1-proteinase inhibitor is a neutrophil chemoattractant after proteolytic inactivation by macrophage elastase.
1988 • 170 citations
Modulation of Cell Proliferation by Cytokeratins K10 and K16
1999 • 170 citations
Pigment epithelium-derived factor (PEDF) in neuroblastoma: a multifunctional mediator of Schwann cell antitumor activity
2001 • 168 citations
Expression of Transforming Growth Factor Beta 1, 2, and 3 Proteins in Keloids
1999 • 159 citations
Functional Implications of the IL-6 Signaling Pathway in Keloid Pathogenesis
2006 • 157 citations
The human keratinocyte two‐dimensional gel protein database (update 1992): Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases
1992 • 125 citations
Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1α and vascular endothelial growth factor
2005 • 125 citations
Measurement of plasma calprotectin as an indicator of arthritis and disease activity in patients with inflammatory rheumatic diseases.
1994 • 122 citations
Keratinocyte-Releasable Stratifin Functions as a Potent Collagenase-Stimulating Factor in Fibroblasts
2004 • 121 citations
The human keratinocyte two‐dimensional gel protein database (update 1995): Mapping components of signal transduction pathways
1995 • 115 citations
α1-Antitrypsin Is Degraded and Non-Functional in Chronic Wounds But Intact and Functional in Acute Wounds: The Inhibitor Protects Fibronectin from Degradation by Chronic Wound Fluid Enzymes
1995 • 112 citations
Macrophage Migration Inhibitory Factor
2005 • 105 citations
Increased Proliferation in Keloid Fibroblasts Woundedin Vitro
1996 • 102 citations
Green Tea Extract and (−)-Epigallocatechin-3-Gallate Inhibit Mast Cell-Stimulated Type I Collagen Expression in Keloid Fibroblasts via Blocking PI-3K/Akt Signaling Pathways
2006 • 101 citations
Complex pattern of the myelo-monocytic differentiation antigens MRP8 and MRP14 during chronic airway inflammation
1992 • 96 citations
Analysis of differentially expressed genes in keloids and normal skin with cDNA microarray
2003 • 96 citations
A Partial Catalog of Proteins Secreted by Epidermal Keratinocytes in Culture
1999 • 95 citations
Dimeric galectin‐1 induces IL‐10 production in T‐lymphocytes: an important tool in the regulation of the immune response
2004 • 94 citations
Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)‐β1–induced collagen synthesis
2007 • 88 citations
Gene expression in human keloids is altered from dermal to chondrocytic and osteogenic lineage
2005 • 88 citations
Upregulation of secretory connective tissue growth factor (CTGF) in keratinocyte‐fibroblast coculture contributes to keloid pathogenesis
2006 • 88 citations
Proliferating activity of dermal fibroblasts in keloids and hypertrophic scars.
1995 • 88 citations
Galectin-1 and Galectin-3 in Chronic Pancreatitis
2000 • 86 citations
TISSUE ALPHA-GLOBULINS IN KELOID FORMATION
1977 • 82 citations
Calgranulin expression in inflammatory dermatoses
1989 • 80 citations
A Proteomic Characterization of the Plasma Membrane of Human Epidermis by High-Throughput Mass Spectrometry
2004 • 79 citations
Collagen Biosynthesis in Normal Human Skin, Normal and Hypertrophic Scar and Keloid
1975 • 74 citations
Activation of NF?B signal pathways in keloid fibroblasts
2004 • 72 citations
Epithelial–mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion
2006 • 70 citations
Tumor Suppressor Maspin Is Up-Regulated during Keratinocyte Senescence, Exerting a Paracrine Antiangiogenic Activity
2004 • 67 citations
Gene expression patterns in isolated keloid fibroblasts
2006 • 65 citations
Comparative Proteomic Profiling of Murine Skin
2003 • 61 citations
The role of the activin system in keloid pathogenesis
2006 • 59 citations
Manganese Superoxide Dismutase Protects the Proliferative Capacity of Confluent Normal Human Fibroblasts
2005 • 57 citations
Hyaluronic acid metabolism in keloid fibroblasts
1995 • 55 citations
The human keratinocyte two‐dimensional protein database (update 1994): Towards an integrated approach to the study of cell proliferation, differentiation and skin diseases
1994 • 54 citations
Increased Fibronectin Production by Cell Lines from Hypertrophic Scar and Keloid
1989 • 53 citations
Protein Profiling of the Human Epidermis from the Elderly Reveals Up-regulation of a Signature of Interferon-γ-induced Polypeptides That Includes Manganese-superoxide Dismutase and the p85β Subunit of Phosphatidylinositol 3-Kinase
2003 • 41 citations
Epidermal expression of the calcium binding surface antigen 27E10 in inflammatory skin diseases
1992 • 40 citations
Immunohistochemical localization of carbonic anhydrase I and II in eccrine sweat glands from control subjects and patients with cystic fibrosis.
1983 • 38 citations
A Controversial Tumor Marker: Is SM22 a Proper Biomarker for Gastric Cancer Cells?
2007 • 37 citations
Decreased Prostaglandin E2 Production by Inflammatory Cytokine and Lower Expression of EP2 Receptor Result in Increased Collagen Synthesis in Keloid Fibroblasts
2006 • 29 citations
Effects of density and cellular aging on collagen synthesis and growth kinetics in keloid and normal skin fibroblasts
1982 • 26 citations
Normal human dermal fibroblasts: Proteomic analysis of cell layer and culture medium
2003 • 24 citations
Immunohistochemical study of carbonic anhydrase isozymes in human skin.
2003 • 12 citations
[Inflammatory rheumatic diseases].
2009 • 5 citations