Inhibition of angiogenesis by tissue inhibitor of metalloproteinase

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Angiogenic Factors

1987 • 3,702 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

THE CHEMOTACTIC EFFECT OF MIXTURES OF ANTIBODY AND ANTIGEN ON POLYMORPHONUCLEAR LEUCOCYTES

1962 • 2,726 citations

Signal transduction from the extracellular matrix.

1993 • 1,727 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

1990 • 1,423 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

1993 • 1,114 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells

1976 • 826 citations

Histology. A Text and Atlas.

1974 • 730 citations

Growth‐promoting activity of tissue inhibitor of metalloproteinases‐1 (TIMP‐1) for a wide range of cells A possible new growth factor in serum

1992 • 705 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

1994 • 660 citations

Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

1992 • 620 citations

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues.

1994 • 485 citations

Identification of an Inhibitor of Neovascularization from Cartilage

1990 • 481 citations

Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development.

1983 • 476 citations

Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene

1989 • 475 citations

Tumor-promoting phorbol esters induce angiogenesis in vitro

1985 • 470 citations

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases.

1989 • 462 citations

Antisense RNA-Induced Reduction in Murine TIMP Levels Confers Oncogenicity on Swiss 3T3 Cells

1989 • 459 citations

Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases.

1992 • 429 citations

Tissue inhibitor of metalloproteinases‐2 inhibits bFGF‐induced human microvascular endothelial cell proliferation

1993 • 362 citations

The Activation of Human Type IV Collagenase Proenzyme

1989 • 347 citations

The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity

1991 • 324 citations

Tumor Cell Invasion Inhibited by TIMP-2

1991 • 324 citations

Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells.

1988 • 312 citations

The Gene Structure of Tissue Inhibitor of Metalloproteinases (TIMP)-3 and Its Inhibitory Activities Define the Distinct TIMP Gene Family

1995 • 295 citations

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1982 • 279 citations

Extracellular matrix‐resident basic fibroblast growth factor: Implication for the control of angiogenesis

1991 • 268 citations

Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor.

1991 • 268 citations

[30] Tissue inhibitors of matrix metalloendopeptidases

1995 • 263 citations

Quantitation of Angiogenesis and Antiangiogenesis in the Chick Embryo Chorioallantoic Membrane

1994 • 246 citations

Growth Stimulation of Human Keratinocytes by Tissue Inhibitor of Metalloproteinases

1991 • 241 citations

The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A

1993 • 237 citations

Lipid Angiogenic Factor From Omentum

1984 • 233 citations

Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid.

1983 • 231 citations

Interstitial Collagenase Is Required for Angiogenesis in Vitro

1994 • 231 citations

Preferential inhibition of 72- and 92-kDa gelatinases by tissue inhibitor of metalloproteinases-2

1991 • 227 citations

Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase.

1985 • 220 citations

Cultured endothelial cell monolayers that restrict the transendothelial passage of macromolecules and electrical current

1984 • 217 citations

Cloning of the cDNA Encoding Human Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) and Mapping of the TIMP3 Gene to Chromosome 22

1994 • 214 citations

Histology – A Text and Atlas

1986 • 214 citations

Fibronectin fragments cause chondrolysis of bovine articular cartilage slices in culture.

1992 • 208 citations

Proteolytic balance and capillary morphogenesis

1990 • 203 citations

Tissue inhibitor of metalloproteinase‐2 (TIMP‐2) has erythroid‐potentiating activity

1992 • 200 citations

Purification and Characterization of Two Related but Distinct Metalloproteinase Inhibitors Secreted by Bovine Aortic Endothelial Cells

1989 • 193 citations

Sorsby's Fundus Dystrophy

1989 • 155 citations

Induction of angiogenesis in chick yolk-sac membrane by polyamines and its inhibition by tissue inhibitors of metalloproteinases (TIMP and TIMP-2)

1990 • 154 citations

Immune modulation of metalloproteinase production in human macrophages. Selective pretranslational suppression of interstitial collagenase and stromelysin biosynthesis by interferon-gamma.

1990 • 146 citations

Angiogenic activity of adipose tissue

1988 • 137 citations

Suppression of Invasion by Inducible Expression of Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) in B 16-F10 Melanoma Cells

1992 • 137 citations

Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts.

1992 • 137 citations

Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP‐3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10

1994 • 135 citations

Fibronectin-degrading proteases from the membranes of transformed cells

1987 • 134 citations

1-Butyryl-Glycerol: A novel angiogenesis factor secreted by differentiating adipocytes

1990 • 124 citations

Differentiation-dependent stimulation of neovascularization and endothelial cell chemotaxis by 3T3 adipocytes.

1982 • 123 citations

Evidence that human rheumatoid synovial matrix metalloproteinase 3 is an endogenous activator of procollagenase

1988 • 120 citations

Tetradecanoyl phorbol acetate stimulates latent collagenase production by cultured human endothelial cells

1980 • 117 citations

Sorsby's Fundus Dystrophy

1989 • 115 citations

Targeted disruption of the tissue inhibitor of metalloproteinases gene increases the invasive behavior of primitive mesenchymal cells derived from embryonic stem cells in vitro.

1992 • 109 citations

K562 cells produce and respond to human erythroid-potentiating activity

1988 • 99 citations

Identification and partial characterization of an inhibitor of collagenase from rabbit bone

1977 • 90 citations

Purification and characterization of human T-lymphocyte-derived erythroid-potentiating activity.

1984 • 88 citations

The 21-kDa protein is a transformation-sensitive metalloproteinase inhibitor of chicken fibroblasts.

1991 • 85 citations

Platelet-derived collagenase inhibitor: characterization and subcellular localization.

1985 • 83 citations

Potent stimulation of vascular endothelial cell growth by differentiated 3T3 adipocytes.

1980 • 83 citations

Angiogenesis

1984 • 82 citations

Production of collagenase and inhibitor (TIMP) by intracranial tumors and dura in vitro

1983 • 75 citations

A fibrosarcoma model derived from mouse embryo cells: Growth properties and secretion of collagenase and metalloproteinase inhibitor (TIMP) by tumour cell lines

1984 • 74 citations

Proteinase Inhibitors

2021 • 73 citations

Assay and purification of naturally occurring inhibitor of angiogenesis

1991 • 73 citations

Metalloproteinase inhibitors from bovine cartilage and body fluids

1984 • 62 citations

Molecular cloning of gene sequences regulated by tumor promoters and mitogens through protein kinase C.

1987 • 55 citations

Extraction of type‐IV collagenase/gelatinase from plasma membranes of human cancer cells

1990 • 51 citations

Transformation-sensitive protein associated with the cell substratum of chicken embryo fibroblasts

1983 • 50 citations

Immunolocalization of collagenase and tissue inhibitor of metalloproteinases (TIMP) in hypertrophic scar tissue

1986 • 38 citations

Production of latent collagenase by human umbilical vein endothelial cells in response to angiogenic preparations

1985 • 38 citations

Heparin potentiation of 3T3‐adipocyte stimulated angiogenesis: Mechanisms of action on endothelial cells

1986 • 37 citations

Localization of collagenase at the basal plasma membrane of a human pancreatic carcinoma cell line.

1990 • 34 citations

The amino-terminal 29- and 72-Kd fragments of fibronectin mediate selective monocyte recruitment

1990 • 31 citations

Cell Motility in Angiogenesis and Tumor Metastasis

1990 • 22 citations

Sorsby's fundus dystrophy. A South African family with a point mutation on the tissue inhibitor of metalloproteinases-3 gene on chromosome 22.

1995 • 19 citations

Purification and biological activities of an angiogenesis factor from human placenta.

1986 • 11 citations

Tissue inhibitor of metalloproteases (TIMP) is matrix associated in aortic tissue: Report of a radioimmunoassay

1990 • 9 citations