Tumor-promoting phorbol esters induce angiogenesis in vitro

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

COLLAGEN SUBSTRATA FOR STUDIES ON CELL BEHAVIOR

1972 • 1,530 citations

Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis

1977 • 1,286 citations

Tumor Angiogenesis

1985 • 1,038 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase.

1985 • 731 citations

Epithelia suspended in collagen gels can lose polarity and express characteristics of migrating mesenchymal cells.

1982 • 642 citations

In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices.

1983 • 616 citations

Capillary endothelial cell cultures: phenotypic modulation by matrix components.

1983 • 611 citations

In vitro studies on the mode of action of the phorbol esters, potent tumor promoters: Part 1

1980 • 477 citations

Tumor Promoters and the Mechanism of Tumor Promotion

1980 • 415 citations

Cell proliferation and migration on collagen substrata in vitro

1980 • 347 citations

Basement Membrane Collagen: Degradation by Migrating Endothelial Cells

1983 • 345 citations

The role of proteinase in cellular invasiveness

1983 • 297 citations

Plasminogen activator and collagenase production by cultured capillary endothelial cells

1982 • 279 citations

Invasion of mesenchyme into three-dimensional collagen gels: A regional and temporal analysis of interaction in embryonic heart tissue

1983 • 265 citations

Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro.

1983 • 261 citations

Macrophage fibrinolytic activity: Identification of two pathways of plasmin formation by intact cells and of a plasminogen activator inhibitor

1982 • 225 citations

Cultured endothelial cell monolayers that restrict the transendothelial passage of macromolecules and electrical current

1984 • 217 citations

ACTIVATION OF PLASMINOGEN: A GENERAL MECHANISM FOR PRODUCING LOCALIZED EXTRACELLULAR PROTEOLYSIS

1978 • 176 citations

Degradation of fibrin and elastin by intact human alveolar macrophages in vitro. Characterization of a plasminogen activator and its role in matrix degradation.

1984 • 166 citations

[29] Collagen as a substrate for cell growth and differentiation

1982 • 165 citations

Molecular Basis of Biological Degradative Processes

1978 • 163 citations

Effects Of Culture Conditions On The Proliferation, Morphology And Migration Of Bovine Aortic Endothelial Cells

1983 • 131 citations

Tumour angiogenesis

1983 • 126 citations

Current concepts and controversies in chemical carcinogenesis

1981 • 126 citations

The many forms and functions of cellular proteinases.

1980 • 118 citations

Tetradecanoyl phorbol acetate stimulates latent collagenase production by cultured human endothelial cells

1980 • 117 citations

Fibroblast adhesion on collagen substrata in the presence and absence of plasma fibronectin

1981 • 103 citations

Interactions of vascular wall cells with collagen gels.

1982 • 99 citations

Lymphocyte migration into three-dimensional collagen matrices: a quantitative study.

1983 • 99 citations

Neutrophil granulocytes: adhesion and locomotion on collagen substrata and in collagen matrices

1982 • 86 citations

Cell migration through three-dimensional gels of native collagen fibres: collagenolytic activity is not required for the migration of two permanent cell lines

1980 • 66 citations

Response of epithelial and mesenchymal cells to culture on basement lamella observed by scanning microscopy*1

1977 • 52 citations

Migration of human neutrophils in hydrated collagen lattices

1982 • 42 citations

Angiogenesis Factor(s)

1981 • 41 citations