The N-terminal domain of tissue inhibitor of metalloproteinases retains metalloproteinase inhibitory activity

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1987 • 5,745 citations

Maturation of the head of bacteriophage T4

1973 • 3,781 citations

Ultrasensitive Stain for Proteins in Polyacrylamide Gels Shows Regional Variation in Cerebrospinal Fluid Proteins

1981 • 2,972 citations

Preparative and analytical purification of DNA from agarose.

1979 • 1,585 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity

1985 • 702 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes

1987 • 474 citations

Matrix metalloproteinase degradation of elastin, type IV collagen and proteoglycan. A quantitative comparison of the activities of 95 kDa and 72 kDa gelatinases, stromelysins-1 and -2 and punctuated metalloproteinase (PUMP)

1991 • 454 citations

Human skin fibroblast collagenase inhibitor. Purification and biochemical characterization.

1983 • 259 citations

Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components

1983 • 222 citations

cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases.

1990 • 202 citations

Disulphide bond assignment in human tissue inhibitor of metalloproteinases (TIMP)

1990 • 176 citations

The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor

1983 • 172 citations

Human Skin Fibroblast Collagenase: Interaction with Substrate and Inhibitor

1985 • 167 citations

Comparison of vertebrate collagenase and gelatinase using a new fluorogenic substrate peptide

1989 • 154 citations

Immunolocalization of tissue inhibitor of metalloproteinases (timp) in human cells characterization and use of a specific antiserum

1985 • 116 citations

Immunoassays for the Detection of Human Collagenase, Stromelysin, Tissue Inhibitor of Metallo-proteinases (TIMP) and Enzyme-Inhibitor Complexes

1990 • 95 citations

Purification of recombinant human prostromelysin. Studies on heat activation to give high-Mr and low-Mr active forms, and a comparison of recombinant with natural stromelysin activities

1991 • 83 citations

The construction of a highly efficient and versatile set of mammalian expression vectors

1989 • 81 citations

Dissociation of tissue inhibitor of metalloproteinases (TIMP) from enzyme complexes yields fully active inhibitor

1989 • 76 citations

Tissue inhibitor of metalloproteinases. Identification of precursor forms synthetized by human fibroblasts in culture

1985 • 33 citations

In vitro synthesis of the active tissue inhibitor of metalloproteinases encoded by a complementary DNA from virus-infected murine fibroblasts.

1988 • 26 citations