Preferential inhibition of 72- and 92-kDa gelatinases by tissue inhibitor of metalloproteinases-2

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Textbook of Rheumatology.

1988 • 593 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

1986 • 531 citations

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases.

1989 • 462 citations

Antisense RNA-Induced Reduction in Murine TIMP Levels Confers Oncogenicity on Swiss 3T3 Cells

1989 • 459 citations

Purification of rabbit bone inhibitor of collagenase

1981 • 352 citations

A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

1979 • 350 citations

The Activation of Human Type IV Collagenase Proenzyme

1989 • 347 citations

Primary structure and cDNA cloning of human fibroblast collagenase inhibitor.

1986 • 274 citations

Purification and characterization of a murine basement membrane collagen-degrading enzyme secreted by metastatic tumor cells.

1983 • 245 citations

Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid.

1983 • 231 citations

Proteinases and extracellular remodeling

1989 • 224 citations

[52] Mammalian collagenases

1981 • 219 citations

Secretion of metalloproteinases by stimulated capillary endothelial cells. I. Production of procollagenase and prostromelysin exceeds expression of proteolytic activity.

1986 • 215 citations

Ras oncogene mediated induction of a 92kDa metalloproteinase; strong correlation with the malignant phenotype

1988 • 209 citations

cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases.

1990 • 202 citations

Purification and characterization of a bone metalloproteinase that degrades gelatin and types IV and V collagen

1985 • 195 citations

Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells.

1990 • 180 citations

The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor

1983 • 172 citations

An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases

1981 • 171 citations

Purification and properties of a gelatin-specific neutral protease from human skin.

1981 • 169 citations

Human Skin Fibroblast Collagenase: Interaction with Substrate and Inhibitor

1985 • 167 citations

A specific inhibitor of vertebrate collagenase produced by human skin fibroblasts.

1979 • 157 citations

Synthesis of collagenase and collagenase inhibitors by osteoblast-like cells in culture

1984 • 125 citations

Current views of collagen degeradation. Progress towards understanding the resorption of connective tissues

1985 • 121 citations

Extracts of human articular cartilage contain an inhibitor of tissue metalloproteinases

1984 • 102 citations

Purification of a Type V Collagen Degrading Metalloproteinase from Rabbit Alveolar Macrophages

1984 • 98 citations

Dissociation of tissue inhibitor of metalloproteinases (TIMP) from enzyme complexes yields fully active inhibitor

1989 • 76 citations

A latent Mr 94,000 gelatin-degrading metalloprotease induced during differentiation of HL-60 promyelocytic leukemia cells: a member of the collagenase family of enzymes.

1990 • 56 citations

Degradation of type I collagen films by mouse osteoblasts is stimulated by 1,25 dihydroxyvitamin D3 and inhibited by human recombinant TIMP (tissue inhibitor of metalloproteinases)

1987 • 38 citations

Differentiation of a human leukemia cell line and expression of collagenase inhibitor.

1985 • 36 citations

Properties of radiolabeled type I, II, and III collagens related to their use as substrates in collagenase assays

1986 • 34 citations

Purification and characterization of a connective-tissue-degrading metalloproteinase from the cytosol of metastatic melanoma cells

1987 • 25 citations

Rapid purification of tissue inhibitor of metalloproteinases from human plasma and identification as a γ-serum protein

1986 • 19 citations