Retinoid-dependent in vitro transcription mediated by the RXR/RAR heterodimer.

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

1992 • 1,751 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

Transcriptional repression by YY1, a human GLI-Krüippel-related protein, and relief of repression by adenovirus E1A protein

1991 • 1,023 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Functional ecdysone receptor is the product of EcR and Ultraspiracle genes

1993 • 936 citations

Retinoids and their receptors in differentiation, embryogenesis, and neoplasia

1991 • 856 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

1993 • 738 citations

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

1991 • 672 citations

Three-dimensional structures of avidin and the avidin-biotin complex.

1993 • 637 citations

Transport and Storage of Vitamin A

1990 • 618 citations

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

1992 • 583 citations

Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle

1993 • 519 citations

The retinoid signaling pathway: molecular and genetic analyses

1994 • 508 citations

Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene.

1990 • 487 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus.

1991 • 464 citations

RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors.

1992 • 446 citations

Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding

1994 • 432 citations

All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs

1992 • 417 citations

Determinants for selective RAR and TR recognition of direct repeat HREs.

1993 • 403 citations

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

1993 • 369 citations

RNA Polymerase B (II) And General Transcription Factors

1990 • 355 citations

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

1992 • 341 citations

RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.

1993 • 305 citations

Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression.

1993 • 262 citations

A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects.

1992 • 256 citations

The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

1994 • 251 citations

Affinity purification of histidine-tagged proteins

1993 • 242 citations

Two different liver-specific factors stimulate in vitro transcription from the human alpha 1-antitrypsin promoter.

1988 • 236 citations

The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex

1990 • 223 citations

Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements.

1994 • 210 citations

Mechanisms of transactivation by retinoic acid receptors

1993 • 156 citations

Yeast and human TFIID with altered DNA-binding specificity for TATA elements

1992 • 155 citations

Different agonist- and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mapping.

1994 • 125 citations

Cooperativity in transactivation between retinoic acid receptor and TFIID requires an activity analogous to E1A

1992 • 116 citations

Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding.

1992 • 108 citations

A single cDNA, hTFIIA/alpha, encodes both the p35 and p19 subunits of human TFIIA.

1993 • 108 citations

Functional characterization of a natural retinoic acid responsive element.

1991 • 100 citations

High expression of functional adenovirus DNA polymerase and precursor terminal protein using recombinant vaccinia virus

1988 • 94 citations

Isolation of a cDNA encoding the largest subunit of TFIIA reveals functions important for activated transcription.

1993 • 88 citations

Different TBP-associated factors are required for mediating the stimulation of transcriptionin vitroby the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor

1993 • 81 citations

Progesterone receptor stimulates transcription of mouse mammary tumour virus in a cell-free system

1990 • 78 citations

Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro.

1990 • 78 citations

Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro.

1992 • 69 citations

Dominant negative retinoid X receptor beta inhibits retinoic acid-responsive gene regulation in embryonal carcinoma cells.

1994 • 66 citations

In vitro activity of the transcription activation functions of the progesterone receptor. Evidence for intermediary factors.

1992 • 59 citations

Residues in the TATA-binding protein required to mediate a transcriptional response to retinoic acid in EC cells

1993 • 58 citations

Ligand-induced alteration of the protease sensitivity of retinoid X receptor alpha.

1994 • 55 citations

The retinoic acid receptor-beta 2 contains two separate cell-specific transactivation domains, at the N-terminus and in the ligand-binding domain.

1993 • 40 citations

Hormone activation of baculovirus expressed progesterone receptors.

1992 • 38 citations

The glucocorticoid receptor hormone binding domain mediates transcriptional activationin vitroin the absence of ligand

1993 • 36 citations

Recombinant thyroid hormone receptor and retinoid Xreceptor stimulate ligand-dependent transcription in vitro.

1994 • 28 citations

Human androgen receptor expressed in HeLa cells activates transcriptionin vitro

1994 • 27 citations

The retinoic acid receptor-beta 2 contains two separate cell-specific transactivation domains, at the N-terminus and in the ligand-binding domain

1993 • 18 citations