Different TBP-associated factors are required for mediating the stimulation of transcriptionin vitroby the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1986 • 6,284 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The drosophila EcR gene encodes an ecdysone receptor, a new member of the steroid receptor superfamily

1991 • 958 citations

The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors.

1986 • 733 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

Negative effect of the transcriptional activator GAL4

1988 • 672 citations

Transcription from a TATA-less promoter requires a multisubunit TFIID complex.

1991 • 618 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

1988 • 588 citations

Activators and targets

1990 • 582 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Mechanism of action of an acidic transcriptional activator in vitro

1991 • 557 citations

Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences

1983 • 477 citations

A novel mediator between activator proteins and the RNA polymerase II transcription apparatus

1990 • 450 citations

Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor

1987 • 434 citations

The cloned human oestrogen receptor contains a mutation which alters its hormone binding properties.

1989 • 428 citations

Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1

1991 • 421 citations

Coactivators for a proline-rich activator purified from the multisubunit human TFIID complex.

1991 • 381 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

Sequence-Specific Antirepression of Histone H1-Mediated Inhibition of Basal RNA Polymerase II Transcription

1991 • 378 citations

TRANSCRIPTION ACTIVATION BY ESTROGEN AND PROGESTERONE RECEPTORS

1991 • 372 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

Reduced binding of TFIID to transcriptionally compromised mutants of VP16

1991 • 362 citations

Factors involved in specific transcription in mammalian RNA polymerase II. Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site.

1987 • 355 citations

Physical Analysis of Transcription Preinitiation Complex Assembly on a Class II Gene Promoter

1988 • 320 citations

Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Separation and characterization of factors mediating accurate transcription by RNA polymerase II.

1982 • 314 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

Identification of two transactlvation domains in the mouse oestrogen receptor

1989 • 303 citations

A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically

1992 • 290 citations

Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.

1990 • 255 citations

The Zta trans-activator protein stabilizes TFIID association with promoter DNA by direct protein-protein interaction.

1991 • 249 citations

Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID.

1991 • 242 citations

Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets

1990 • 221 citations

Advances in RNA polymerase II transcription

1992 • 149 citations

A Potent GAL4 Derivative Activates Transcription at a Distance in Vitro

1990 • 148 citations

Transcriptional regulation of the HIV-1 promoter by NF-kappa B in vitro.

1992 • 146 citations

The mammalian TFIID protein is present in two functionally distinct complexes.

1991 • 142 citations

The immunoglobulin heavy-chain B-lymphocyte enhancer efficiently stimulates transcription in non-lymphoid cells.

1986 • 140 citations

Regulation of gene expression by nuclear hormone receptors

1989 • 133 citations

The acidic transcriptional activator GAL-VP16 acts on preformed template-committed complexes.

1992 • 125 citations

Purification of a factor specific for the upstream element of the adenovirus-2 major late promoter.

1986 • 123 citations

Cloning of the 62-Kilodalton Component of Basic Transcription Factor BTF2

1992 • 120 citations

The transcriptional activation function located in the hormone-binding domain of the human oestrogen receptor is not encoded in a single exon.

1989 • 107 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Role of Transcription Factors IIA, IID, and IIB during Formation of a Transcription-Competent Complex

1990 • 87 citations

Mechanism of estrogen receptor-dependent transcription in a cell-free system.

1990 • 84 citations

Transcription initiated by RNA polymerase II and transcription factors from liver. Structure and action of transcription factors epsilon and tau.

1991 • 78 citations

In vitrosquelching of activated transcription by serum response factor: evidence for a common coactivator used by muliple transcriptional activators

1992 • 67 citations

Evidence for a factor required for transcriptional stimulation by the chimeric acidic activator GAL-VP16 in HeLa cell extracts.

1991 • 57 citations

Expression and Function of the Human Estrogen Receptor in Yeast

1988 • 36 citations

Identification of a coactivator that increases activation of transcription by serum response factor and GAL4-VP16 in vitro.

1992 • 32 citations

Mechanism of Estrogen Receptor-Dependent Transcription in a Cell-Free System

1990 • 17 citations