Recombinant thyroid hormone receptor and retinoid Xreceptor stimulate ligand-dependent transcription in vitro.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

1992 • 1,751 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

1993 • 940 citations

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

1992 • 583 citations

Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer

1989 • 508 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

A lymphocyte-specific enhancer in the mouse immunoglobulin κ gene

1984 • 410 citations

Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation.

1992 • 363 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity.

1993 • 307 citations

Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression.

1993 • 262 citations

The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex

1990 • 223 citations

Half-site spacing and orientation determines whether thyroid hormone and retinoic acid receptors and related factors bind to DNA response elements as monomers, homodimers, or heterodimers.

1992 • 216 citations

Thyroid hormone receptor binds to a site in the rat growth hormone promoter required for induction by thyroid hormone.

1987 • 183 citations

Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected β type thyroid hormone receptor

1989 • 177 citations

Functional characterization and receptor binding studies of the malic enzyme thyroid hormone response element.

1991 • 134 citations

The Conserved Ninth C-Terminal Heptad in Thyroid Hormone and Retinoic Acid Receptors Mediates Diverse Responses by Affecting Heterodimer but Not Homodimer Formation

1993 • 132 citations

3,5,3′-Triiodothyronine (T₃) Receptor-Auxiliary Protein (TRAP) Binds DNA and Forms Heterodimers with the T₃Receptor

1991 • 130 citations

Cooperativity in transactivation between retinoic acid receptor and TFIID requires an activity analogous to E1A

1992 • 116 citations

Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription

1990 • 110 citations

In Vitro Transcription Enhancement by Purified Derivatives of the Glucocorticoid Receptor

1989 • 107 citations

Triiodothyronine (T3) differentially affects T3-receptor/retinoic acid receptor and T3-receptor/retinoid X receptor heterodimer binding to DNA

1992 • 102 citations

Heterodimerization of thyroid hormone (TH) receptor with H-2RIIBP (RXR beta) enhances DNA binding and TH-dependent transcriptional activation.

1992 • 88 citations

Mechanism of estrogen receptor-dependent transcription in a cell-free system.

1990 • 84 citations

Thyroid Hormone Receptors Form Distinct Nuclear Protein-Dependent and Independent Complexes with a Thyroid Hormone Response Element

1990 • 82 citations

Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro.

1990 • 78 citations

Estrogen-Dependent in Vitro Transcription from the Vitellogenin Promoter in Liver Nuclear Extracts

1988 • 78 citations

Phosphorylation stimulates the transcriptional activity of the human beta 1 thyroid hormone nuclear receptor.

1992 • 76 citations

Reconstitution of retinoid X receptor function and combinatorial regulation of other nuclear hormone receptors in the yeast Saccharomyces cerevisiae.

1993 • 67 citations

Retinoic acid-dependent transactivation of major histocompatibility complex class I promoters by the nuclear hormone receptor H-2RIIBP in undifferentiated embryonal carcinoma cells.

1992 • 64 citations

Direct interaction of the tau 1 transactivation domain of the human glucocorticoid receptor with the basal transcriptional machinery.

1993 • 63 citations

Divergent effects of 9-cis-retinoic acid receptor on positive and negative thyroid hormone receptor-dependent gene expression.

1993 • 61 citations

Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70.

1991 • 59 citations

The NF-kappa B and Sp1 motifs of the human immunodeficiency virus type 1 long terminal repeat function as novel thyroid hormone response elements.

1993 • 58 citations

Ligand-dependent, Pit-1/growth hormone factor-1 (GHF-1)-independent transcriptional stimulation of rat growth hormone gene expression by thyroid hormone receptors in vitro.

1993 • 43 citations

Hormone activation of baculovirus expressed progesterone receptors.

1992 • 38 citations

Estrogen receptor level determines sex-specific in vitro transcription from the Xenopus vitellogenin promoter.

1990 • 33 citations

Two upstream elements activate transcription of a major histocompatibility complex class I genein vitro

1992 • 31 citations

H-2RIIBP expressed from a baculovirus vector binds to multiple hormone response elements.

1992 • 25 citations

Mechanism of Estrogen Receptor-Dependent Transcription in a Cell-Free System

1990 • 17 citations

The NF-κB and Sp1 Motifs of the Human Immunodeficiency Virus Type 1 Long Terminal Repeat Function as Novel Thyroid Hormone Response Elements

1993 • 14 citations

Direct Interaction of the τ₁ Transactivation Domain of the Human Glucocorticoid Receptor with the Basal Transcriptional Machinery

1993 • 10 citations