Diazoxide Reverses the Enhanced Expression of KATP Subunits in Cholinergic Neurons Caused by Exposure to Aβ1-42

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

1983 • 3,028 citations

Soluble pool of A? amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1999 • 1,787 citations

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

1992 • 1,602 citations

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

1995 • 1,310 citations

A Family of Sulfonylurea Receptors Determines the Pharmacological Properties of ATP-Sensitive K+ Channels

1996 • 968 citations

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

2003 • 547 citations

A VIEW OF SUR/K_IR6.X, K_ATP CHANNELS

1998 • 514 citations

Physiological and pathophysiological roles of ATP-sensitive K+ channels

2003 • 500 citations

β‐Amyloid inhibits integrated mitochondrial respiration and key enzyme activities

2001 • 459 citations

Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea‐sensitive but ATP‐insensitive K+ channel.

1997 • 390 citations

Acetylcholine, Aging, and Alzheimer's Disease

1997 • 355 citations

Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation

2002 • 202 citations

Heterogeneity and selectivity of the degeneration of cholinergic neurons in the basal forebrain of patients with Alzheimer's disease

1993 • 201 citations

β-Amyloid Fragment 25–35 Causes Mitochondrial Dysfunction in Primary Cortical Neurons

2002 • 193 citations

Molecular physiology of neuronal K-ATP channels

2001 • 160 citations

Diazoxide induces delayed pre‐conditioning in cultured rat cortical neurons

2003 • 141 citations

Mitochondrial ATP-Sensitive Potassium Channel Activation Protects Cerebellar Granule Neurons From Apoptosis Induced by Oxidative Stress

2003 • 124 citations

Physicochemical characteristics of soluble oligomeric Aβand their pathologic role in Alzheimer's disease

2005 • 116 citations

Behavioral impairments after lesions of the nucleus basalis by ibotenic acid and quisqualic acid

1991 • 106 citations

Mitochondrial Potassium Channel Opener Diazoxide Preserves Neuronal-Vascular Function After Cerebral Ischemia in Newborn Pigs

1999 • 105 citations

Amyloid-β Deposition Is Associated with Decreased Hippocampal Glucose Metabolism and Spatial Memory Impairment in APP/PS1 Mice

2004 • 103 citations

Neuroprotective effects of bcl‐2 overexpression in hippocampal cultures: interactions with pathways of oxidative damage

2002 • 95 citations

Oligomerization and fibril assembly of the amyloid-β protein

2000 • 86 citations

Investigation of the subunit composition and the pharmacology of the mitochondrial ATP-dependent K+ channel in the brain

2003 • 86 citations

Myocardial ischemia induces differential regulation of KATP channel gene expression in rat hearts.

1997 • 70 citations

The mitochondrial KATP channel opener BMS-191095 induces neuronal preconditioning

2004 • 66 citations

Activation of mitochondrial ATP‐sensitive potassium channels increases cell viability against rotenone‐induced cell death

2003 • 59 citations

Diazoxide acts more as a PKC‐ɛ activator, and indirectly activates the mitochondrial K_ATP channel conferring cardioprotection against hypoxic injury

2006 • 46 citations

β-Amyloid peptide 25–35 regulates basal and hormone-stimulated Ca2+ levels in cultured rat astrocytes

1998 • 45 citations

Reciprocal regulation of expression of pore-forming KATP channel genes by hypoxia.

2001 • 32 citations

Brain energy metabolism in Alzheimer’s disease: 99mTc-HMPAO SPECT imaging during verbal fluency and role of astrocytes in the cellular mechanism of 99mTc-HMPAO retention

2001 • 30 citations

Channel activators regulate ATP‐sensitive potassium channel (KIR6.1) expression in chick cardiomyocytes

1997 • 25 citations

The Role of Aβ Peptides in Alzheimers Disease

2005 • 23 citations

Differential sensitivity of atrial and ventricular KATP channels to metabolic inhibition

2003 • 22 citations

Effects of Aβ1–42 on the Subunits of KATP Expression in Cultured Primary Rat Basal Forebrain Neurons

2008 • 14 citations

Iptakalim, opener of KATP, reverses the enhanced expression of genes encoding KATP subunits in spontaneously hypertensive rats

2005 • 9 citations

mRNA expression alterations of inward rectifier potassium channels in rat brain with cholinergic impairment

2002 • 9 citations

Alterations in the Expression of ATP-Sensitive Potassium Channel Subunit mRNA after Acute Peripheral Nerve and Spinal Cord Injury

2006 • 7 citations