Mitochondrial ATP-Sensitive Potassium Channel Activation Protects Cerebellar Granule Neurons From Apoptosis Induced by Oxidative Stress

Mitochondria and Apoptosis

1998 • 8,909 citations

The mitochondrial permeability transition pore and its role in cell death

1999 • 2,326 citations

THE MITOCHONDRIAL DEATH/LIFE REGULATOR IN APOPTOSIS AND NECROSIS

1998 • 1,982 citations

Mitochondria and Neuronal Survival

2000 • 1,206 citations

Glutamate release in severe brain ischaemia is mainly by reversed uptake

2000 • 1,105 citations

Cardioprotective Effect of Diazoxide and Its Interaction With Mitochondrial ATP-Sensitive K ⁺ Channels

1997 • 1,032 citations

Activation and Cleavage of Caspase-3 in Apoptosis Induced by Experimental Cerebral Ischemia

1998 • 899 citations

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1993 • 886 citations

Mitochondrial ATP-Dependent Potassium Channels

1998 • 825 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 442 citations

Diazoxide-Induced Cardioprotection Requires Signaling Through a Redox-Sensitive Mechanism

2001 • 396 citations

Mitochondrial ATP-Sensitive Potassium Channels Attenuate Matrix Ca ²⁺ Overload During Simulated Ischemia and Reperfusion

2001 • 362 citations

An improved and rapid HPLC-EC method for the isocratic separation of amino acid neurotransmitters from brain tissue and microdialysis perfusates

1988 • 349 citations

Mitochondrial contributions to tissue damage in stroke

2002 • 320 citations

Identification and Properties of a Novel Intracellular (Mitochondrial) ATP-sensitive Potassium Channel in Brain

2001 • 282 citations

Mitochondrial ATP-Sensitive Potassium Channels Inhibit Apoptosis Induced by Oxidative Stress in Cardiac Cells

2001 • 281 citations

Adenosine-5′-triphosphate-sensitive ion channels in neonatal rat cultured central neurones

1988 • 270 citations

Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat.

1995 • 258 citations

Blockade of the Mitochondrial Permeability Transition Pore Diminishes Infarct Size in the Rat after Transient Middle Cerebral Artery Occlusion

1999 • 218 citations

Activation of Mitochondrial ATP-Dependent Potassium Channels Protects Neurons against Ischemia-Induced Death by a Mechanism Involving Suppression of Bax Translocation and Cytochrome c Release

2002 • 214 citations

Exposure to hydrogen peroxide induces cell death via apoptosis in cultured rat cortical neurons

1994 • 208 citations

Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation

2002 • 202 citations

Cyclosporin A protects against ischemia-reperfusion injury in the brain

1992 • 177 citations

Suppression of Neuronal and Cardiac Transient Outward Currents by Viral Gene Transfer of Dominant-Negative Kv4.2 Constructs

1997 • 171 citations

Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices

1993 • 157 citations

Massive Persistent Release of Excitatory Amino Acids Following Human Occlusive Stroke

1995 • 151 citations

Adenosine Primes the Opening of Mitochondrial ATP-Sensitive Potassium Channels

2000 • 108 citations

Mitochondrial Potassium Channel Opener Diazoxide Preserves Neuronal-Vascular Function After Cerebral Ischemia in Newborn Pigs

1999 • 105 citations

K+ channel openers protect hippocampal neurons against oxidative injury and amyloid β-peptide toxicity

1996 • 96 citations

Potassium channel openers depolarize hippocampal mitochondria

2001 • 94 citations

Pharmacologic characterization of BMS-191095, a mitochondrial K(ATP) opener with no peripheral vasodilator or cardiac action potential shortening activity.

2001 • 94 citations

Pharmacologically induced preconditioning with diazoxide: a novel approach to brain protection31The Thoracic Surgery Directors Association (TSDA) Resident Research Award, sponsored by Medtronic, Inc, was established in 1990 to encourage resident research in cardiothoracic surgery. Abstracts submitted to The Society of Thoracic Surgeons (STS) Program Committee representing research performed by residents were forwarded to the TSDA to be considered for this award. The abstracts were reviewed by …

2001 • 90 citations

Diazoxide protects mitochondria from anoxic injury: Implications for myopreservation

2001 • 83 citations

Increased intracerebral excitatory amino acids and nitric oxide after hypothermic circulatory arrest

1999 • 37 citations

Efflux of glutathione conjugate of monochlorobimane from striatal and cortical neurons.

2001 • 17 citations