A Family of Sulfonylurea Receptors Determines the Pharmacological Properties of ATP-Sensitive K+ Channels

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

ATP-regulated K+ channels in cardiac muscle

1983 • 2,350 citations

Reconstitution of I _KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor

1995 • 1,703 citations

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

1995 • 1,310 citations

Analysis of radioligand binding experiments

1985 • 1,247 citations

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

1984 • 1,199 citations

Hyperpolarizing Vasodilators Activate ATP-sensitive K ⁺ Channels in Arterial Smooth Muscle

1989 • 1,197 citations

CFTR as a cAMP-Dependent Regulator of Sodium Channels

1995 • 1,074 citations

Adenosine 5'-Triphosphate-Sensitive Potassium Channels

1988 • 888 citations

Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.

1992 • 766 citations

Opposite effects of tolbutamide and diazoxide on the ATP-dependent K+ channel in mouse pancreatic ?-cells

1986 • 572 citations

Identification of the cystic fibrosis gene.

1990 • 509 citations

THE SULPHONYLUREA RECEPTOR MAY BE AN ATP-SENSITIVE POTASSIUM CHANNEL

1985 • 507 citations

Sequence, tissue distribution, and chromosomal localization of mRNA encoding a human glucose transporter-like protein.

1988 • 426 citations

Voltage-dependent ATP-sensitive potassium channels of skeletal muscle membrane

1985 • 417 citations

The ABC of channel regulation

1995 • 375 citations

Cardiac ATP-sensitive K+ channels: regulation by intracellular nucleotides and K+ channel-opening drugs

1995 • 309 citations

Moving together: K+ channel openersand ATP-sensitive K+ channels

1989 • 285 citations

Adenosine-5′-triphosphate-sensitive ion channels in neonatal rat cultured central neurones

1988 • 270 citations

The jellyfish green fluorescent protein: A new tool for studying ion channel expression and function

1995 • 248 citations

The potassium channel opener cromakalim (BRL 34915) activates ATP-dependent K+ channels in isolated cardiac myocytes

1988 • 193 citations

The regulation of ATP‐sensitive K+ channel activity in intact and permeabilized rat ventricular myocytes.

1990 • 170 citations

Promiscuous coupling between the sulphonylurea receptor and inwardly rectifying potassium channels

1996 • 159 citations

ATP-dependent potassium channels of muscle cells: Their properties, regulation, and possible functions

1991 • 147 citations

Characterization, purification, and affinity labeling of the brain [3H]glibenclamide-binding protein, a putative neuronal ATP-regulated K+ channel.

1988 • 145 citations

Characterization of the sulfonylurea receptor on beta cell membranes.

1988 • 120 citations

Potassium channel openers act through an activation of ATP-sensitive K+ channels in guinea-pig cardiac myocytes

1989 • 116 citations

Photoaffinity labeling and partial purification of the beta cell sulfonylurea receptor using a novel, biologically active glyburide analog.

1990 • 100 citations

Specific receptors for sulfonylureas in brain and in a B-cell tumor of the rat

1982 • 76 citations

Direct photoaffinity labeling of the putative sulfonylurea receptor in rat β‐cell tumor membranes by [³H]glibenclamide

1988 • 75 citations

Multiple actions of pinacidil on adenosine triphosphate‐sensitive potassium channels in guinea‐pig ventricular myocytes.

1990 • 71 citations

Specificity of photolabeling of beta-cell membrane proteins with an 125I-labeled glyburide analog.

1992 • 47 citations

A binding site for [3H]glipizide in the rat cerebral cortex

1987 • 45 citations