Specific involvement of caspases in the differentiation of monocytes into macrophages

A simple salting out procedure for extracting DNA from human nucleated cells

1988 • 20,341 citations

Two CD95 (APO-1/Fas) signaling pathways

1998 • 3,045 citations

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1999 • 1,540 citations

Caspase-1 processes IFN-γ-inducing factor and regulates LPS-induced IFN- γ production

1997 • 1,172 citations

Molecular Cloning of the Interleukin-1β Converting Enzyme

1992 • 1,115 citations

Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors

1998 • 984 citations

Hsp27 negatively regulates cell death by interacting with cytochrome c

2000 • 972 citations

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.

1993 • 959 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 729 citations

Inhibition of ICE Family Proteases by Baculovirus Antiapoptotic Protein p35

1995 • 645 citations

Transcription Factors, Normal Myeloid Development, and Leukemia

1997 • 637 citations

Caspase Activation Is Required for T Cell Proliferation

1999 • 462 citations

Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins

1998 • 421 citations

Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

1999 • 418 citations

Dendritic Cells as the Terminal Stage of Monocyte Differentiation

1998 • 405 citations

The Mitochondrion in Cell Death Control: Certainties and Incognita

2000 • 404 citations

Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1

1999 • 388 citations

Early Activation of Caspases during T Lymphocyte Stimulation Results in Selective Substrate Cleavage in Nonapoptotic Cells

1999 • 387 citations

Caspase Activation Is Required for Terminal Erythroid Differentiation

2001 • 383 citations

A Role for Caspases in Lens Fiber Differentiation

1998 • 294 citations

Regulation of cell division cycle progression by bcl-2 expression: a potential mechanism for inhibition of programmed cell death.

1996 • 284 citations

Mouse models of cell death

2001 • 270 citations

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

2002 • 265 citations

Apoptotic Role of Fas/Fas Ligand System in the Regulation of Erythropoiesis

1999 • 262 citations

Flice-Inhibitory Protein Expression during Macrophage Differentiation Confers Resistance to FAS-Mediated Apoptosis

1999 • 229 citations

Caspase activation in the terminal differentiation of human epidermal keratinocytes

1999 • 196 citations

Regulation of Apoptosis and Cell Cycle Progression by MCL1

2000 • 164 citations

Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells

2000 • 143 citations

The Novel Triterpenoid CDDO Induces Apoptosis and Differentiation of Human Osteosarcoma Cells by a Caspase-8 Dependent Mechanism

2001 • 136 citations

Chromatin remodeling in development and differentiation

2001 • 126 citations

Apoptosis is rapidly triggered by antisense depletion of MCL-1 in differentiating U937 cells

2000 • 112 citations

Antiapoptotic Signaling Generated by Caspase-Induced Cleavage of RasGAP

2001 • 111 citations

Caspase activation without death

1999 • 104 citations

Members of the Bcl-2 and Caspase Families Regulate Nuclear Degeneration during Chick Lens Fibre Differentiation

1999 • 95 citations

Indication of an involvement of interleukin-1 beta converting enzyme- like protease in intramedullary apoptotic cell death in the bone marrow of patients with myelodysplastic syndromes

1996 • 89 citations

Human intestinal epithelial cell survival: differentiation state-specific control mechanisms

2001 • 88 citations

Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity

1999 • 88 citations

Mitochondria-targeting drugs arsenic trioxide and lonidamine bypass the resistance of TPA-differentiated leukemic cells to apoptosis

2001 • 84 citations

Processing and Release of IL-16 from CD4+ But Not CD8+ T Cells Is Activation Dependent

1999 • 82 citations

c-Maf Induces Monocytic Differentiation and Apoptosis in Bipotent Myeloid Progenitors

1999 • 78 citations

12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.

1986 • 74 citations

Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells

1999 • 52 citations

Caffeine Sensitizes Human H358 Cell Line to p53-mediated Apoptosis by Inducing Mitochondrial Translocation and Conformational Change of BAX Protein

2001 • 52 citations

Inhibition of cell death by lens-specific overexpression of bcl-2 in transgenic mice

1997 • 52 citations

Expression and activity of caspases 1 and 3 in myelodysplastic syndromes

2000 • 45 citations

Requirement for caspase activation in monocytic differentiation of myeloid leukemia cells

2000 • 41 citations

12-O-tetradecanoylphorbol-13-acetate-induced Apoptosis Is Mediated by Tumor Necrosis Factor α in Human Monocytic U937 Cells

1999 • 29 citations

Apoptotic Role of Fas/Fas Ligand System in the Regulation of Erythropoiesis

1999 • 19 citations

CELL DEATH PATHWAYS AS TARGETS FOR ANTICANCER DRUGS

2002 • 8 citations

Bleomycin-induced differentiation of bcl-2-transfected U937 leukemia cells.

1996 • 8 citations