Requirement for caspase activation in monocytic differentiation of myeloid leukemia cells

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

1996 • 5,133 citations

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

1997 • 4,921 citations

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

1997 • 4,728 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

1998 • 3,603 citations

Cytochemical Identification of Monocytes and Granulocytes

1971 • 2,735 citations

Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

1976 • 2,468 citations

Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

1995 • 1,453 citations

MKK3- and MKK6-Regulated Gene Expression Is Mediated by the p38 Mitogen-Activated Protein Kinase Signal Transduction Pathway

1996 • 1,286 citations

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization

1998 • 1,226 citations

The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression

1987 • 1,180 citations

Integration of MAP Kinase Signal Transduction Pathways at the Serum Response Element

1995 • 935 citations

BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteases

1996 • 911 citations

A License to Kill

1996 • 649 citations

Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents

1995 • 486 citations

Protein kinase C isozymes and substrates

1996 • 440 citations

Role for Bcl-x_Las an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis

1997 • 397 citations

Ionizing radiation regulates expression of the c-jun protooncogene.

1990 • 297 citations

Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis.

1997 • 259 citations

Activation of calcium-activated, phospholipid-dependent protein kinase (protein kinase C) by new classes of tumor promoters: Teleocidin and debromoaplysiatoxin

1984 • 181 citations

Activation of beta-isozyme of protein kinase C (PKC beta) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes. Studies with PKC beta-defective PET mutant.

1994 • 135 citations

Activation of a CrmA-insensitive, p35-sensitive Pathway in Ionizing Radiation-induced Apoptosis

1997 • 125 citations

Protein kinase C-beta is required for macrophage differentiation of human HL-60 leukemia cells.

1994 • 121 citations

cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.

1992 • 72 citations

Functional Role for Protein Kinase Cβ as a Regulator of Stress-Activated Protein Kinase Activation and Monocytic Differentiation of Myeloid Leukemia Cells

1999 • 68 citations

Multiple doses of diacylglycerol and calcium ionophore are necessary to activate AP-1 enhancer activity and induce markers of macrophage differentiation.

1990 • 60 citations

Internucleosomal DNA fragmentation during phorbol ester-induced monocytic differentiation and G0/G1 arrest.

1992 • 59 citations

Protein kinase C beta gene expression is associated with susceptibility of human promyelocytic leukemia cells to phorbol ester-induced differentiation.

1992 • 56 citations

Transcriptional regulation of c-jun gene expression by arabinofuranosylcytosine in human myeloid leukemia cells.

1990 • 48 citations

Decreased expression of type II protein kinase C in HL-60 variant cells resistant to induction of cell differentiation by phorbol diester.

1990 • 38 citations

High Yield Purification of a Four Subunit caa3-Type Cytochrome Oxidase from the Thermophilic Bacterium Bacillus PS3 Using Fast Protein Liquid Chromatography

1995 • 17 citations

Bryostatin 1 activates protein kinase C and induces monocytic differentiation of HL-60 cells

1988 • 11 citations

All-trans retinoic acid reverses phorbol ester resistance in a human myeloid leukemia cell line

1994 • 3 citations

Phospholipase C activates protein kinase C and induces monocytic differentiation of HL-60 cells

1988 • 1 citations