Caspase Activation Is Required for T Cell Proliferation

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Inhibition of death receptor signals by cellular FLIP

1997 • 2,577 citations

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.

1995 • 2,142 citations

FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis

1998 • 893 citations

Conversion of Membrane-bound Fas(CD95) Ligand to Its Soluble Form Is Associated with Downregulation of Its Proapoptotic Activity and Loss of Liver Toxicity

1998 • 789 citations

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1994 • 708 citations

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1998 • 704 citations

Fas transduces activation signals in normal human T lymphocytes.

1993 • 521 citations

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

1998 • 504 citations

Activation interferes with the APO-1 pathway in mature human T cells

1993 • 466 citations

A Role for FADD in T Cell Activation and Development

1998 • 241 citations

T cell receptor‐induced Fas ligand expression in cytotoxic T lymphocyte clones is blocked by protein tyrosine kinase inhibitors and cyclosporin A

1994 • 206 citations

Fas antigen signals proliferation of normal human diploid fibroblast and its mechanism is different from tumor necrosis factor receptor

1995 • 132 citations

Newly discovered role for Fas ligand in the cell-cycle arrest of CD4+ T cells

1998 • 109 citations