A Domain with Homology to Neuronal Calcium Sensors Is Required for Calcium-dependent Activation of Diacylglycerol Kinase α

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

1997 • 38,984 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

RASMOL: biomolecular graphics for all

1995 • 2,601 citations

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

1960 • 2,598 citations

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

Micellization of mixed nonionic surface active agents

1975 • 984 citations

Detection of Calcium Binding Proteins by 45Ca Autoradiography on Nitrocellulose Membrane after Sodium Dodecyl Sulfate Gel Electrophoresis1

1984 • 772 citations

Molecular mechanics of calcium–myristoyl switches

1997 • 462 citations

Taxonomy and function of C1 protein kinase C homology domains

1997 • 350 citations

Mammalian Diacylglycerol Kinases, a Family of Lipid Kinases with Signaling Functions

1999 • 284 citations

Three-dimensional structure of recoverin, a calcium sensor in vision

1993 • 274 citations

Intracellular neuronal calcium sensor proteins: a family of EF-hand calcium-binding proteins in search of a function

1999 • 253 citations

Effect of calcium ions on the activity, heat stability, and structure of trypsin

1970 • 188 citations

sn-1,2-Diacylglycerol kinase of Escherichia coli. Mixed micellar analysis of the phospholipid cofactor requirement and divalent cation dependence.

1986 • 148 citations

Three-dimensional Structure of Guanylyl Cyclase Activating Protein-2, a Calcium-sensitive Modulator of Photoreceptor Guanylyl Cyclases

1999 • 145 citations

Attenuation of sn-1,2-diacylglycerol second messengers by diacylglycerol kinase. Inhibition by diacylglycerol analogs in vitro and in human platelets.

1986 • 134 citations

Porcine 80-kDa diacylglycerol kinase is a calcium-binding and calcium/phospholipid-dependent enzyme and undergoes calcium-dependent translocation.

1991 • 131 citations

Different effects of sphingosine, R59022 and anionic amphiphiles on two diacylglycerol kinase isozymes purified from porcine thymus cytosol

1989 • 123 citations

Gene cloning, sequence, expression and in situ localization of 80 kDa diacylglycerol kinase specific to oligodendrocyte of rat brain

1992 • 120 citations

Phosphatidic Acid Generation through Interleukin 2 (IL-2)-induced α-Diacylglycerol Kinase Activation Is an Essential Step in IL-2-mediated Lymphocyte Proliferation

1996 • 118 citations

Selectivity of the diacylglycerol kinase inhibitor 3-{2-(4-[bis-(4-fluorophenyl)methylene]-1-piperidinyl)ethyl}-2,3-dihydro-2-thioxo-4(1H)quinazolinone (R59949) among diacylglycerol kinase subtypes

2000 • 118 citations

Crystal structure of recombinant bovine neurocalcin.

1999 • 99 citations

Cloning and expression of a cytoskeleton-associated diacylglycerol kinase that is dominantly expressed in cerebellum.

1994 • 99 citations

Diacylglycerol kinase

1997 • 81 citations

The binding of Ca2 to trypsinogen and its relation to the mechanism of activation

1967 • 80 citations

EF-hand motifs of α, β and γ isoforms of diacylglycerol kinase bind calcium with different affinities and conformational changes

1997 • 77 citations

Changes in Biological Activity and Folding of Guanylate Cyclase-Activating Protein 1 as a Function of Calcium

1998 • 77 citations

The C-terminal part of diacylglycerol kinase α lacking zinc fingers serves as a catalytic domain

1996 • 66 citations

Activation of Human Neutrophil NADPH Oxidase by Phosphatidic Acid or Diacylglycerol in a Cell-free System

1999 • 59 citations

Purification and characterization of membrane-bound and cytosolic forms of diacylglycerol kinase from rat brain.

1990 • 57 citations

The regulatory role of EF-hand motifs of pig 80K diacylglycerol kinase as assessed using truncation and deletion mutants

1991 • 51 citations

Diacylglycerol kinase and phosphatidic acid phosphatase—enzymes metabolizing lipid second messengers

1993 • 47 citations

Occurrence of immunoreactive 80 kDa and non-immunoreactive diacylglycerol kinases in different pig tissues.

1988 • 46 citations

Phospholipase D-derived Products in the Regulation of 12- -Tetradecanoylphorbol-13-acetate-stimulated Prostaglandin Synthesis in Madin-Darby Canine Kidney Cells

1996 • 45 citations

Purification and characterization of cytosolic diacylglycerol kinases of human platelets.

1990 • 43 citations

Arachidonoyl-diacylglycerol Kinase SPECIFIC IN VITRO INHIBITION BY POLYPHOSPHOINOSITIDES SUGGESTS A MECHANISM FOR REGULATION OF PHOSPHATIDYLINOSITOL BIOSYNTHESIS

1995 • 40 citations

S100A1 Utilizes Different Mechanisms for Interacting with Calcium-Dependent and Calcium-Independent Target Proteins

1998 • 39 citations

[17] Diacylglycerol kinase from escherichia coli

1992 • 36 citations

Amino Acid Residues of S-modulin Responsible for Interaction with Rhodopsin Kinase

2000 • 34 citations

A highly conserved homologue of bovine neurocalcin in Drosophila melanogaster is a Ca(2+)-binding protein expressed in neuronal tissues.

1994 • 32 citations

The different effects of sphingosine on diacylglycerol kinase isozymes in Jurkat cells, a human T-cell line

1993 • 29 citations

The Role of Calcium-binding Sites in S-modulin Function

1998 • 22 citations

[30] Expression and characterization of calcium-myristoyl switch proteins

1995 • 21 citations

Epidermal Growth Factor Receptor Stimulation of Diacylglycerol Kinase

1997 • 9 citations