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Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer's disease: II. Primary and secondary visual cortex

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Increased Brain β-Amyloid Load, Phosphorylated Tau, and Risk of Alzheimer Disease Associated With an Intronic CYP46 Polymorphism

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On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells

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Myelin development and nutritional insufficiency

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Amyloid-β and τ serve antioxidant functions in the aging and Alzheimer brain

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Prolonged corticosterone treatment of adult rats inhibits the proliferation of oligodendrocyte progenitors present throughout white and gray matter regions of the brain

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Aβ42-Peptide Assembly on Lipid Bilayers

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A role for oligodendrocyte‐derived IGF‐1 in trophic support of cortical neurons

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MR evaluation of age-related increase of brain iron in young adult and older normal males

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Schizophrenia Breakdown in the Well-regulated Lifelong Process of Brain Development and Maturation

2002 • 182 citations

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Evidence for changes in the Alzheimer's disease brain cortical membrane structure mediated by cholesterol

1992 • 177 citations

Response of Glial Cells to Ischemia: Roles of Reactive Oxygen Species and Glutathione

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Synopsis of function and dysfunction of the frontal lobe

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Abnormal localization of iron regulatory protein in Alzheimer's disease

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Cholesterol Accumulates in Senile plaques of Alzheimer Disease patients and in Transgenic APP_swMice

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No global neocortical nerve cell loss in brains from patients with senile dementia of Alzheimer's type

1994 • 167 citations

Statin effects on cholesterol micro-domains in brain plasma membranes

2003 • 166 citations

Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes

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Neuropsychological and neurophysiological changes in healthy adult humans across the age range

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Oxidative processes in Alzheimer's disease: the role of Aβ-metal interactions

2000 • 154 citations

Reduction of Plasma 24S-Hydroxycholesterol (Cerebrosterol) Levels Using High-Dosage Simvastatin in Patients With Hypercholesterolemia

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In Vitro Studies of Ferritin Iron Release and Neurotoxicity

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Myelin glycolipids and their functions

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Binding of Zn(II), Cu(II), and Fe(II) ions to alzheimer's Aß peptide studied by fluorescence

1999 • 144 citations

Oligodendrocyte development and thyroid hormone

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Cholesterol domains in biological membranes

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In vivo MR evaluation of age-related increases in brain iron.

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Magnetization transfer imaging in normal aging, mild cognitive impairment, and Alzheimer's disease

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The Relationship between Intracellular Free Iron and Cell Injury in Cultured Neurons, Astrocytes, and Oligodendrocytes

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Vulnerability of Select Neuronal Types to Alzheimer's Disease

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Repeated prenatal corticosteroid administration delays myelination of the corpus callosum in fetal sheep

2001 • 140 citations

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Oxidative Regulation of Fatty Acid-Induced Tau Polymerization

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Curvilinear regression course of human brain lipid composition changes with age

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In vivo evaluation of brain iron in Alzheimer's disease and normal subjects using MRI

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A Plasticity‐Based Theory of the Pathogenesis of Alzheimer's Disease

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Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain

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Cholesterol‐dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons

2001 • 129 citations

Oligodendrocyte development and thyroid hormone

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The Biology of the Oligodendrocyte

1984 • 127 citations

β‐Amyloid Neurotoxicity In Vitro: Evidence of Oxidative Stress but Not Protection by Antioxidants

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Oligodendroglial precursor cell susceptibility to hypoxia is related to poor ability to cope with reactive oxygen species

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Multiple system atrophy: cellular and molecular pathology.

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Cholesterol-dependent Generation of a Seeding Amyloid β-Protein in Cell Culture

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Pathways of Neurosteroid Biosynthesis in Cell Lines from Human Brain

2000 • 119 citations

Neurosteroids: recent findings

2001 • 118 citations

The Magnitude of Brain Lipid Peroxidation Correlates with the Extent of Degeneration but Not with Density of Neuritic Plaques or Neurofibrillary Tangles or with APOE Genotype in Alzheimer's Disease Patients

1999 • 118 citations

Recent advances in brain cholesterol dynamics: Transport, domains, and Alzheimer's disease

1999 • 116 citations

Function of β‐amyloid in cholesterol transport: a lead to neurotoxicity

2002 • 113 citations

The hemochromatosis gene affects the age of onset of sporadic Alzheimer’s disease

2001 • 112 citations

Apoptosis of astrocytes with enhanced lysosomal activity and oligodendrocytes in white matter lesions in Alzheimer's disease

2002 • 112 citations

Transition metal‐mediated glycoxidation accelerates cross‐linking of β‐amyloid peptide

2000 • 109 citations

Spatial structure of the human alpha rhythm: global correlation in adults and local correlation in children

1999 • 108 citations

Transbilayer Distribution of Cholesterol Is Modified in Brain Synaptic Plasma Membranes of Knockout Mice Deficient in the Low‐Density Lipoprotein Receptor, Apolipoprotein E, or Both Proteins

1997 • 107 citations

Diffuse Vacuolization (Spongiosis) and Arteriolosclerosis in the Frontal White Matter Occurs in Vascular Dementia

1996 • 106 citations

Relationship Between Blood Pressure and Subcortical Lesions in Healthy Elderly People

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Cerebrovascular Pathology in Alzheimer's Disease and Leukoaraiosis

2000 • 105 citations

Gender and age modify the association between APOE and AD-related neuropathology

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White Matter Changes in the Gerbil Brain Under Chronic Cerebral Hypoperfusion

1998 • 103 citations

Electrically evoked auditory brainstem response in peripherally myelin-deficient mice

1995 • 103 citations

Association of Dementia Severity With Cortical Gray Matter and Abnormal White Matter Volumes in Dementia of the Alzheimer Type

1996 • 102 citations

Anatomic subdivisions in human temporal cortical neuronal activity related to recent verbal memory

2001 • 99 citations

Caspase-3-Mediated Cleavage of Amyloid Precursor Protein and Formation of AmyloidβPeptide in Traumatic Axonal Injury

2002 • 98 citations

Cholesterol is necessary both for the toxic effect of Aβ peptides on vascular smooth muscle cells and for Aβ binding to vascular smooth muscle cell membranes

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Lipids in the Nervous System of Different Species as a Function of Age: Brain, Spinal Cord, Peripheral Nerve, Purified Whole Cell Preparations, and Subcellular Particulates: Regulatory Mechanisms and Membrane Structure

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Filamentous Tau Pathology in Nerve Cells, Astrocytes, and Oligodendrocytes of Aged Baboons

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In vivo actions of fibroblast growth factor-2 and insulin-like growth factor-I on oligodendrocyte development and myelination in the central nervous system

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Neuropathological distinction between Parkinson's dementia and Parkinson's plus Alzheimer's disease

1989 • 95 citations

Statins in the Prevention and Treatment of Alzheimer Disease

2002 • 94 citations

Decreased myelin lipids in Alzheimer's disease and vascular dementia

1989 • 94 citations

Decreased brain levels of 2′,3′-cyclic nucleotide-3′-phosphodiesterase in Down syndrome and Alzheimer’s disease

2001 • 93 citations

Temporal Sequence of Alzheimer’s Disease-Related Pathology

1999 • 93 citations

Problems of cell death in neurodegeneration and Alzheimer's Disease

2001 • 91 citations

Neurodegenerative Changes Associated with β-Amyloid Deposition in the Brains of Mice Carrying Mutant Amyloid Precursor Protein and Mutant Presenilin-1 Transgenes

2001 • 90 citations

Alzheimer's disease : advances in etiology, pathogenesis, and therapeutics

2001 • 89 citations

Quadratic trajectories of brain myelin content: unifying construct for neuropsychiatric disorders

2003 • 88 citations

Oligodendrocyte Precursor Cells from Different Brain Regions Express Divergent Properties Consistent with the Differing Time Courses of Myelination in These Regions

2002 • 88 citations

Brain maturation may be arrested in chronic cocaine addicts

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Increased Water Diffusion in Cerebral White Matter in Alzheimer’s Disease

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X-ray diffraction evidence for myelin disorder in brain from humans with alzheimer's disease

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The Role of Hormone Replacement Therapy in the Prevention of Alzheimer Disease

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In vitro polymerization of oxidized tau into filaments

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Membrane Components Separate Early-Onset Alzheimer's Disease From Senile Dementia of the Alzheimer Type

1996 • 84 citations

Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice

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Life Span Changes in Electrophysiological Measures of Inhibition

1996 • 82 citations

Gelsolin-related spinal and cerebral amyloid angiopathy

1999 • 82 citations

Magnetic resonance imaging evidence of “silent” cerebrovascular toxicity in cocaine dependence

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Is hemochromatosis a risk factor for Alzheimer's disease?

2001 • 81 citations

Age-related progression of tau pathology in brains of baboons

2000 • 79 citations

Age-impaired impulse flow from nucleus basalis to cortex

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Endoplasmic Reticulum Stress in PLP-Overexpressing Transgenic Rats: Gray Matter Oligodendrocytes Are More Vulnerable than White Matter Oligodendrocytes

2002 • 69 citations

The stabilization of ferrous iron by a toxic β-amyloid fragment and by an aluminum salt

1999 • 69 citations

Senile plaques do not progressively accumulate with normal aging

1994 • 68 citations

Preservation of Prefrontal Cortical Volume in Behaviorally Characterized Aged Macaque Monkeys

1999 • 68 citations

Ambulatory blood pressure and brain atrophy in the healthy elderly

2002 • 68 citations

Iron Modulates the Differentiation of a Distinct Population of Glial Precursor Cells into Oligodendrocytes

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The neurotoxicity of amyloid beta protein in aged primates

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Cholesterol and Alzheimer's disease

2002 • 64 citations

Changes in lipid phase behaviour in human myelin during maturation and aging

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White matter ischaemia

1999 • 63 citations

The Role of Metal Ions in Oxidative Processes and Aging

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Fiber Content of the Fornix in Schizophrenia: Lack of Evidence for a Primary Limbic Encephalopathy

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Lead Exposure Delays the Differentiation of Oligodendroglial Progenitors in Vitro

2001 • 57 citations

Inherited disorders of cholesterol biosynthesis

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New evidence that the Alzheimer β-amyloid peptide does not spontaneously form free radicals: An ESR study using a series of spin-traps

2001 • 55 citations

Alzheimer’s disease drug discovery targeted to the APP mRNA 5′Untranslated region

2002 • 54 citations

The relationship between the aggregational state of the amyloid‐β peptides and free radical generation by the peptides

2001 • 54 citations

Oxidative Stress Induces Dephosphorylation of τ in Rat Brain Primary Neuronal Cultures

1997 • 53 citations

Interhemispheric disconnection syndrome in Alzheimer’s disease

1998 • 53 citations

Incidence of axonal injury in human brain tissue

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The effects of aging on the frequency of nerve fibers in rhesus monkey striate cortex

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Bad for the Heart, Bad For the Mind?

2001 • 50 citations

Hypoxic/ischemic insult alters ferritin expression and myelination in neonatal rat brains

2001 • 49 citations

Dietary iron and the integrity of the developing rat brain: a study with the artificially-reared rat pup.

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Changes in the axonal conduction velocity of pyramidal tract neurons in the aged cat

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Neurochemical Changes in White Matter

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Insulin-like growth factor-I (IGF-I) protects myelination from undernutritional insult: Studies of transgenic mice overexpressing IGF-I in brain

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Serum amyloid A in Alzheimer's disease brain is predominantly localized to myelin sheaths and axonal membrane

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Hypoxic/ischemic insult alters ferritin expression and myelination in neonatal rat brains

2001 • 39 citations

Neuronal signals regulate neurotrophin expression in oligodendrocytes of the basal forebrain

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Ultrastructural analyses of β-amyloid in the aged dog brain: Neuronal β-amyloid is localized to the plasma membrane

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Exposure of rats to a high but not low dose of ethanol during early postnatal life increases the rate of loss of optic nerve axons and decreases the rate of myelination

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The distribution of iron in the brain: A phylogenetic analysis using iron histochemistry

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In Vivo Metabolism of Oligodendroglial Lipids

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Effects of Early Undernutrition on the Brain Insulin‐Like Growth Factor‐I System

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Modulation of myelin basic protein-induced aggregation and fusion of liposomes by cholesterol, aliphatic aldehydes and alkanes

1986 • 30 citations

The Expression of Ferritin Subunits and Iron in Oligodendrocytes in Neonatal Porcine Brains

1996 • 30 citations

Prenatal Methylmercury Exposure and Children: Neurologic, Developmental, and Behavioral Research

1998 • 26 citations

Oligodendrocytes express different isoforms of ?-amyloid precursor protein in chemically defined cell culture conditions: In situ hybridization and immunocytochemical detection

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Paul Flechsig’s System of Myelogenetic Cortical Localization in the Light of Recent Research in Neuroanatomy and Neurophysiology Part I

1981 • 24 citations

Auditory and visual event-related potentials and flash visual evoked potentials in Alzheimer's disease: correlations with Mini-Mental State Examination and Raven's Coloured Progressive Matrices

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http://C.Elegans: Mining the functional genomic landscape

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Ascorbate promotes low density lipoprotein oxidation in the presence of ferritin

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Giant cell arteritis in a 19-year-old woman associated with vertebral artery aneurysm and subarachnoid hemorrhage.

2001 • 15 citations

Demonstration and distribution of tau‐positive glial coiled body‐like structures in white matter and white matter threads in early onset Alzheimer’s disease

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Structure and Organisation of Fibre Systems

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Dementia of Alzheimer type with and without multiple lacunar infarctions: Evaluation of white matter lesions

2000 • 9 citations

Paul Flechsig’s System of Myelogenetic Cortical Localization In the Light of Recent Research in Neuroanatomy and Neurophysiology Part II

1981 • 8 citations

A-beta, tau and the fabrication of tangles

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Ear see rescue

2001 • 1 citations

Deleted Work

1955 • 0 citations