Pathogenesis of Leukoaraiosis

Pathologic correlates of incidental MRI white matter signal hyperintensities

1993 • 1,512 citations

Clinical Correlates of White Matter Findings on Cranial Magnetic Resonance Imaging of 3301 Elderly People

1996 • 1,428 citations

A white matter disorder in dementia of the Alzheimer type: A pathoanatomical study

1986 • 999 citations

Cerebral white matter lesions, vascular risk factors, and cognitive function in a population‐based study

1994 • 997 citations

Leuko-Araiosis

1987 • 724 citations

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy maps to chromosome 19q12

1993 • 663 citations

Cerebral White Matter Is Highly Vulnerable to Ischemia

1996 • 590 citations

Regulation of large cerebral arteries and cerebral microvascular pressure.

1990 • 583 citations

Incidental subcortical lesions identified on magnetic resonance imaging in the elderly. I. Correlation with age and cerebrovascular risk factors.

1986 • 582 citations

Autoregulation of cerebral blood flow in hypertensive patients. The modifying influence of prolonged antihypertensive treatment on the tolerance to acute, drug-induced hypotension.

1976 • 541 citations

The Significance of Cerebral White Matter Abnormalities 100 Years After Binswanger’s Report

1995 • 537 citations

Diurnal blood pressure variations and silent cerebrovascular damage in elderly patients with hypertension.

1992 • 463 citations

White matter signal abnormalities in normal individuals: correlation with carotid ultrasonography, cerebral blood flow measurements, and cerebrovascular risk factors.

1988 • 441 citations

PERIVENTRICULAR LESIONS IN THE WHITE MATTER ON MAGNETIC RESONANCE IMAGING IN THE ELDERLY

1991 • 437 citations

White Matter Changes in Healthy Elderly Persons Correlate With Attention and Speed of Mental Processing

1993 • 417 citations

Features of the cerebral vascular pattern that predict vulnerability to perfusion or oxygenation deficiency: an anatomic study.

1990 • 395 citations

Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study.

1994 • 351 citations

Histopathologic correlates of white matter changes on MRI in Alzheimer's disease and normal aging

1995 • 341 citations

The Human Periventricular Arterial Blood Supply and the Anatomy of Cerebral Infarctions

1971 • 315 citations

Autosomal dominant leukoencephalopathy and subcortical ischemic stroke. A clinicopathological study.

1993 • 308 citations

Pathological alterations of the cerebral microvasculature in Alzheimer's disease and related dementing disorders

1994 • 297 citations

Vascular Risk Factors and Leuko-Araiosis

1987 • 290 citations

Periventricular venous collagenosis: association with leukoaraiosis.

1995 • 278 citations

The incidence of cerebral amyloid angiopathy in Alzheimer's disease

1975 • 276 citations

Glial activation and white matter changes in the rat brain induced by chronic cerebral hypoperfusion: an immunohistochemical study

1994 • 270 citations

Leuko-Araiosis on Magnetic Resonance Imaging and Speed of Mental Processing

1990 • 261 citations

Association of deep white matter infarction with chronic communicating hydrocephalus: implications regarding the possible origin of normal-pressure hydrocephalus.

1991 • 257 citations

Leukoencephalopathy in diffuse hemorrhagic cerebral amyloid angiopathy

1985 • 254 citations

Hypoxic-Ischemic Leukoencephalopathy in Man

1976 • 228 citations

Magnetic Resonance Signal Abnormalities in Asymptomatic Individuals: Their Incidence and Functional Correlates

1989 • 217 citations

Neuropsychologic correlates of MRI white matter hyperintensities

1993 • 209 citations

Pathologic Correlates of Increased Signals of the Centrum Ovale on Magnetic Resonance Imaging

1993 • 190 citations

Cerebral lesions on magnetic resonance imaging, heart disease, and vascular risk factors in subjects without stroke. A population-based study.

1994 • 189 citations

Medullary arteries in aging and dementia.

1991 • 184 citations

Further Observations on the Pathology of Subcortical Lesions Identified on Magnetic Resonance Imaging

1992 • 169 citations

Clinicopathologic correlations of cranial magnetic resonance imaging of periventricular white matter

1990 • 169 citations

A quantitative MRI study of vascular dementia

1992 • 165 citations

Neuronal damage and decrease of central acetylcholine level following permanent occlusion of bilateral common carotid arteries in rat

1995 • 163 citations

Selective reduction of blood flow to white matter during hypotension in newborn dogs: A possbile mechanism of periventricular leukomalacia

1982 • 157 citations

Could Wallerian degeneration contribute to "leuko-araiosis" in subjects free of any vascular disorder?

1991 • 156 citations

Normal Pressure Hydrocephalus and Hypertensive Cerebrovascular Disease

1974 • 154 citations

Periventricular white matter lucency and cerebral blood flow autoregulation in hypertensive patients.

1994 • 154 citations

An Autopsy Study of Cerebrovascular Accident in Diabetes Mellitus

1962 • 149 citations

A morphometric study of the blood-brain barrier in Alzheimer's disease.

1992 • 148 citations

Leukoaraiosis: correlation of MR and CT findings with blood flow, atrophy, and cognition.

1990 • 143 citations

Subcortical arteriosclerotic encephalopathy: a clinical and radiological investigation.

1981 • 142 citations

Cortical Abnormalities Associated With Subcortical Lesions in Vascular Dementia

1995 • 139 citations

A quantitative analysis of blood-brain barrier ultrastructure in the aging human

1987 • 138 citations

NEUROPATHOLOGICAL CHANGES LATE IN CEREBRAL EDEMA: THE RELATIONSHIP TO TRAUMA, HYPERTENSIVE DISEASE AND BINSWANGERʼS ENCEPHALOPATHY

1963 • 138 citations

Cerebral circulation and oxygen metabolism associated with subclinical periventricular hyperintensity as shown by magnetic resonance imaging

1990 • 138 citations

Idiopathic normal pressure hydrocephalus and systemic hypertension

1987 • 131 citations

Cerebral blood flow and oxygen metabolism in patients with vascular dementia of the Binswanger type.

1990 • 128 citations

Microvasculature in Brain Biopsy Specimens from Patients with Alzheimer's Disease: An Immunohistochemical and Ultrastructural Study

1994 • 125 citations

Communicating hydrocephalus induced by mechanically increased amplitude of the intraventricular cerebrospinal fluid pressure: Experimental studies

1978 • 125 citations

Pressures in the Pial Arterial Microcirculation of the Cat during Changes in Systemic Arterial Blood Pressure

1972 • 123 citations

Leukoaraiosis and dementia in hypertensive patients.

1992 • 123 citations

Lack of Difference in Brain Hyperintensities Between Patients With Early Alzheimer's Disease and Control Subjects

1994 • 122 citations

Relationship between vascular factors and white matter low attenuation of the brain

1993 • 118 citations

Leukoaraiosis correlates with cerebral hypoperfusion in vascular dementia.

1991 • 110 citations

Dyke Award. The search for human telencephalic ventriculofugal arteries.

1991 • 107 citations

Twenty-four-hour variation of blood pressure in vascular dementia of the Binswanger type.

1991 • 106 citations

Physiological Responses of Local Areas of the Cerebral Circulation in Experimental Primates Determined by the Method of Hydrogen Clearance

1973 • 105 citations

Regional Cerebral Blood Flow in Patients With Leuko-Araiosis and Atherosclerotic Carotid Artery Disease

1990 • 93 citations

Circulations of the cerebral hemispheres

1965 • 93 citations

Leukoaraiosis, intracerebral hemorrhage, and arterial hypertension.

1990 • 93 citations

Decreased cerebrovascular dilatory capacity in subjects with asymptomatic periventricular hyperintensities.

1994 • 86 citations

Arteriolar Tortuosity of the White Matter in Aging and Hypertension. A Microradiographic Study

1994 • 85 citations

Pathological findings correlated with magnetic resonance imaging in subcortical arteriosclerotic encephalopathy (Binswanger's disease).

1989 • 84 citations

Cerebral changes in chronic hypertension: Combined permeability and immunohistochemical studies

1984 • 84 citations

Anatomy and Embryology of Cerebral Circulation

1968 • 83 citations

Lack of Relationship Between Leukoaraiosis and Carotid Artery Disease

1995 • 80 citations

White matter lucencies on computed tomography, subacute arteriosclerotic encephalopathy (Binswanger's disease), and blood pressure.

1987 • 70 citations

Centrifugal Elements in the Vascular Pattern of the Deep Intracerebral Blood Supply

1969 • 65 citations

White Matter Lesions and Disequilibrium in Older People

1995 • 65 citations

Neuronal control of brain microvessel function

1985 • 64 citations

Leukoencephalopathy Following Carbon Monoxide Asphyxia

1959 • 63 citations

Histological observations on Wallerian degeneration in the spinal cord of the baboon,Papio papio

1969 • 60 citations

The controversy of the periventricular white matter circulation: a review of the anatomic literature.

1991 • 58 citations

The Cardiovascular Outcome of Patients With Motor Impairment and Extensive Leukoaraiosis

1995 • 58 citations

Pathology of small artery disease.

1993 • 57 citations

Significance of Periventricular Hemodynamics in Normal Pressure Hydrocephalus

1992 • 57 citations

Cumulative white matter changes in the gerbil brain under chronic cerebral hypoperfusion

1992 • 54 citations

Subcortical arteriosclerotic encephalopathy (Binswanger's type) and cortical infarcts in a young normotensive patient.

1982 • 54 citations

Cerebrospinal fluid proteins in patients with leucoaraiosis: Possible abnormalities in blood-brain barrier function

1993 • 51 citations

Neuropathologic changes in the gerbil brain after chronic hypoperfusion.

1993 • 51 citations

Does the Severity of Leukoaraiosis Contribute to Senile Dementia?

1992 • 48 citations

CT changes associated with normal aging of the human brain

1994 • 44 citations

A Demyelinating Disorder Associated With Cerebrovascular Amyloid Angiopathy

1976 • 41 citations

White matter lesions and normal-pressure hydrocephalus: Binswanger disease or Hakim syndrome?

1991 • 38 citations

The significance of periventricular lucency on computed tomography: Experimental study with canine hydrocephalus

1981 • 38 citations

Predictors of Leukoaraiosis in Elderly Neurological Patients

1991 • 37 citations

Leukb-Araiosis and Cerebral Hypoperfusion Compared in Elderly Normals and Alzheimer's Dementia

1992 • 32 citations

White Matter Hyperintensities May Correspond to Areas of Increased Blood Volume

1990 • 31 citations

White Matter Lesions and Cognitive Deterioration in Presymptomatic Carriers of the Amyloid Precursor Protein Gene Codon 693 Mutation

1996 • 31 citations

Pathogenesis of subcortical hyperintense lesions on magnetic resonance imaging of the brain. Observations in patients undergoing controlled therapeutic internal carotid artery occlusion.

1993 • 30 citations

Binswanger's disease in the absence of chronic arterial hypertension

1992 • 25 citations

1H and31P magnetic resonance spectroscopic imaging of white matter signal hyperintensity areas in elderly subjects

1995 • 22 citations

Histopathological Correlates of Leuko-Araiosis in Patients with Ischemic Stroke

1989 • 20 citations

Amyloid beta protein deposition in brains from elderly subjects with leukoaraiosis

1991 • 18 citations

Anastomoses in the Vascular Bed of the Human Cerebrum

1974 • 18 citations

A Comparative 1-123 IMP SPECT Study in Binswanger??s Disease and Alzheimer??s Disease

1993 • 10 citations