Double-Stranded RNA as a Template for Gene Silencing

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1998 • 14,674 citations

An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

2000 • 2,945 citations

RNAi

2000 • 2,596 citations

The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans

1999 • 1,286 citations

Targeted mRNA degradation by double-stranded RNA in vitro

1999 • 845 citations

mut-7 of C. elegans, Required for Transposon Silencing and RNA Interference, Is a Homolog of Werner Syndrome Helicase and RNaseD

1999 • 745 citations

Gene silencing in Neurospora crassa requires a protein homologous to RNA-dependent RNA polymerase

1999 • 653 citations

RNA-triggered gene silencing

1999 • 623 citations

EGO-1 is related to RNA-directed RNA polymerase and functions in germ-line development and RNA interference in C. elegans

2000 • 546 citations

Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families

1999 • 530 citations

RNA interference: genetic wand and genetic watchdog

2000 • 309 citations

Gene silencing in worms and fungi

2000 • 251 citations

A genetic link between co-suppression and RNA interference in C. elegans

2000 • 214 citations

Long RNA hairpins that contain inosine are present in Caenorhabditis elegans poly(A) ⁺ RNA

1999 • 136 citations

Depletion of yeast RNase III blocks correct U2 3' end formation and results in polyadenylated but functional U2 snRNA

1998 • 123 citations

Purification of the Xenopus laevis double-stranded RNA adenosine deaminase

1994 • 110 citations

Substrate structure requirements of the Pac1 ribonuclease from Schizosaccharmyces pombe.

1997 • 39 citations

Dissociation of Long-Chain Duplex RNA Can Occur Via Strand Displacement in Vitro: Biological Implications

1996 • 35 citations