T-cell subpopulations in the development of atopic and contact allergy

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

Lymphocyte traffic control by chemokines

2001 • 1,225 citations

Dendritic cell regulation of TH1-TH2 development

2000 • 1,136 citations

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

1999 • 1,030 citations

The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells

1999 • 839 citations

Differentiation of T Regulatory Cells by Immature Dendritic Cells

2001 • 500 citations

T cell–mediated Fas-induced keratinocyte apoptosis plays a key pathogenetic role in eczematous dermatitis

2000 • 473 citations

The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics

2001 • 390 citations

Mast Cells Control Neutrophil Recruitment during T Cell–Mediated Delayed-Type Hypersensitivity Reactions through Tumor Necrosis Factor and Macrophage Inflammatory Protein 2

2000 • 384 citations

Interleukin (Il)-4 Is a Major Regulatory Cytokine Governing Bioactive IL-12 Production by Mouse and Human Dendritic Cells

2000 • 376 citations

A Th2 Chemokine, TARC, Produced by Keratinocytes May Recruit CLA+CCR4+ Lymphocytes into Lesional Atopic Dermatitis Skin

2000 • 342 citations

Cutting Edge: The Orphan Chemokine Receptor G Protein-Coupled Receptor-2 (GPR-2, CCR10) Binds the Skin-Associated Chemokine CCL27 (CTACK/ALP/ILC)

2000 • 327 citations

Keratinocytes from patients with atopic dermatitis and psoriasis show a distinct chemokine production profile in response to T cell–derived cytokines

2001 • 300 citations

Major histocompatibility complex class I‐restricted CD8⁺ T cells and class II‐restricted CD4⁺ T cells, respectively, mediate and regulate contact sensitivity to dinitrofluorobenzene

1995 • 291 citations

Interleukin-17 is Produced by Both Th1 and Th2 Lymphocytes, and Modulates Interferon-γ- and Interleukin-4-Induced Activation of Human Keratinocytes

2000 • 289 citations

Atopic Dermatitis Is Associated with a Functional Mutation in the Promoter of the C-C Chemokine RANTES

2000 • 274 citations

Cytotoxicity Is Mandatory for CD8+ T Cell–mediated Contact Hypersensitivity

1999 • 258 citations

Dendritic cells as a major source of macrophage-derived chemokine/CCL22in vitro andin vivo

2001 • 258 citations

Human CD4+ T Lymphocytes with Remarkable Regulatory Functions on Dendritic Cells and Nickel-Specific Th1 Immune Responses

2000 • 241 citations

CD4+ Th1 and CD8+ Type 1 Cytotoxic T Cells Both Play a Crucial Role in the Full Development of Contact Hypersensitivity

2000 • 229 citations

Cellular and immunologic mechanisms in atopic dermatitis

2001 • 221 citations

Chemokine Receptor Expression and Function in CD4+ T Lymphocytes with Regulatory Activity

2001 • 218 citations

CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses

2001 • 218 citations

Skin Homing (Cutaneous Lymphocyte-Associated Antigen-Positive) CD8+ T Cells Respond to Superantigen and Contribute to Eosinophilia and IgE Production in Atopic Dermatitis

1999 • 197 citations

Patients with Allergic Contact Dermatitis to Nickel and Nonallergic Individuals Display Different Nickel-Specific T Cell Responses. Evidence for the Presence of Effector CD8+ and Regulatory CD4+ T Cells

1998 • 192 citations

IL-4 Is a Mediator of IL-12p70 Induction by Human Th2 Cells: Reversal of Polarized Th2 Phenotype by Dendritic Cells

2000 • 180 citations

Differential and Sequential Expression of Multiple Chemokines during Elicitation of Allergic Contact Hypersensitivity

2001 • 178 citations

Evidence for Functional Relevance of CTLA-4 in Ultraviolet-Radiation-Induced Tolerance

2000 • 162 citations

Keratinocyte-Derived Monocyte Chemoattractant Protein 1 (MCP-1): Analysis in a Transgenic Model Demonstrates MCP-1 Can Recruit Dendritic and Langerhans Cells to Skin

1995 • 161 citations

Removal of the majority of epidermal Langerhans cells by topical or systemic steroid application enhances the effector phase of murine contact hypersensitivity.

1995 • 152 citations

Fc epsilon receptor I on dendritic cells delivers IgE-bound multivalent antigens into a cathepsin S-dependent pathway of MHC class II presentation.

1998 • 149 citations

Disparate Cytotoxic Activity of Nickel-Specific CD8+ and CD4+ T Cell Subsets Against Keratinocytes

2000 • 148 citations

Fcε Receptor I on Dendritic Cells Delivers IgE-Bound Multivalent Antigens into a Cathepsin S-Dependent Pathway of MHC Class II Presentation

1998 • 121 citations

Effector and regulatory T cells in allergic contact dermatitis

2001 • 118 citations

IL-4 Enhances Keratinocyte Expression of CXCR3 Agonistic Chemokines

2000 • 110 citations

A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases

2001 • 110 citations

CCR4+ memory CD4+ T lymphocytes are increased in peripheral blood and lesional skin from patients with atopic dermatitis

2001 • 108 citations

Signal Transducer and Activator of Transcription 6 Is Essential in the Induction of Contact Hypersensitivity

2000 • 108 citations

Inhibition of Allergic Contact Dermatitis to DNCB But Not to Oxazolone in Interleukin-4-Deficient Mice

1999 • 98 citations

Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells

2001 • 90 citations

Human T cell subset commitment determined by the intrinsic property of antigen: the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more IL-4 and less IFN-γ

2001 • 85 citations

Evidence for common genetic elements in allergic disease

2000 • 83 citations

Characterization of epitopes recognized by hapten-specific CD4+ T cells.

1995 • 80 citations

Contact Hypersensitivity in MHC Class II-Deficient Mice Depends on CD8 T Lymphocytes Primed by Immunostimulating Langerhans Cells

1998 • 74 citations

Structural complexity of antigenic determinants for class I MHC-restricted, hapten-specific T cells. Two qualitatively differing types of H-2Kb-restricted TNP epitopes.

1993 • 71 citations

Essential Role of Lymph Nodes in Contact Hypersensitivity Revealed in Lymphotoxin-α–Deficient Mice

2001 • 61 citations

Expression of cutaneous lymphocyte-associated antigen on human CD4+ and CD8+ Th2 cells

2000 • 57 citations

Dysregulated Activation of Activator Protein 1 in Keratinocytes of Atopic Dermatitis Patients with Enhanced Expression of Granulocyte/Macrophage-Colony Stimulating Factor

2000 • 53 citations

A Comparative Study of the Expression of Cytotoxic Proteins in Allergic Contact Dermatitis and Psoriasis

2001 • 53 citations

Helper T-cell responses elicited by Der p 1–pulsed dendritic cells and recombinant IL-12 in atopic and healthy subjects

2000 • 40 citations

The Role of Chemokines in Cutaneous Allergic Inflammation

1999 • 33 citations

Down-regulation of IL-12 by topical corticosteroids in chronic atopic dermatitis

2000 • 30 citations

Activation of Nickel-Specific CD4+ T Lymphocytes in the Absence of Professional Antigen-Presenting Cells

2002 • 25 citations

Allergen-specific immune deviation from a T H2 to a T H1 response induced by dendritic cells and collagen type I

1999 • 16 citations

Decreased levels of CXCR3 transcripts in peripheral blood mononuclear cells from patients with atopic dermatitis and with cutaneous diseases associated with eosinophilia

2001 • 5 citations