Mast Cells Control Neutrophil Recruitment during T Cell–Mediated Delayed-Type Hypersensitivity Reactions through Tumor Necrosis Factor and Macrophage Inflammatory Protein 2

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

Chemokines

2000 • 3,773 citations

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

ROLE OF CYTOKINES IN RHEUMATOID ARTHRITIS

1996 • 2,527 citations

The Pathophysiology of Tumor Necrosis Factors

1992 • 1,880 citations

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes.

1996 • 1,196 citations

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

1996 • 1,167 citations

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

1996 • 1,121 citations

Fundamental Immunology

1999 • 1,011 citations

Mast cells as a source of both preformed and immunologically inducible TNF-α/cachectin

1990 • 975 citations

Rheumatoid Arthritis

1996 • 960 citations

Critical protective role of mast cells in a model of acute septic peritonitis

1996 • 942 citations

CCR5⁺and CXCR3⁺T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions

1999 • 839 citations

Early molecular events in the induction phase of contact sensitivity.

1992 • 660 citations

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease.

1994 • 599 citations

An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis.

1995 • 487 citations

Th1/Th2 Cells

1999 • 475 citations

Inflammatory Skin Diseases, T Cells, and Immune Surveillance

1999 • 474 citations

Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance.

1996 • 444 citations

Mast Cells Are Essential for Early Onset and Severe Disease in a Murine Model of Multiple Sclerosis

2000 • 427 citations

Mast Cells Can Amplify Airway Reactivity and Features of Chronic Inflammation in an Asthma Model in Mice

2000 • 400 citations

Chemokine expression in murine experimental allergic encephalomyelitis

1995 • 363 citations

Tumor necrosis factor is a critical mediator in hapten induced irritant and contact hypersensitivity reactions.

1991 • 341 citations

Seeing the wood for the trees: the forgotten role of neutrophils in rheumatoid arthritis

1997 • 327 citations

Human mast cells produce IL-8.

1993 • 302 citations

Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent. Partial inhibition of the reaction with antiserum against tumor necrosis factor-alpha.

1991 • 298 citations

Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis.

1995 • 269 citations

Tumor necrosis factor: a master-regulator of leukocyte movement

2000 • 242 citations

Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice

1993 • 193 citations

Human Intestinal Mast Cells Are Capable of Producing Different Cytokine Profiles: Role of IgE Receptor Cross-Linking and IL-4

2000 • 173 citations

Challenging Cytokine Redundancy: Inflammatory Cell Movement and Clinical Course of Experimental Autoimmune Encephalomyelitis Are Normal in Lymphotoxin-deficient, but Not Tumor Necrosis Factor–deficient, Mice

1998 • 170 citations

The mast cell in health and disease

1990 • 170 citations

Strictures in Crohn’s disease are characterised by an accumulation of mast cells colocalised with laminin but not with fibronectin or vitronectin

1999 • 170 citations

In Autoimmune Diabetes the Transition from Benign to Pernicious Insulitis Requires an Islet Cell Response to Tumor Necrosis Factor α

1999 • 164 citations

Modulation of neutrophil influx in glomerulonephritis in the rat with anti-macrophage inflammatory protein-2 (MIP-2) antibody.

1995 • 163 citations

Mast cells are an important cellular source of tumour necrosis factor α in human intestinal tissue

1999 • 160 citations

Expression and regulation of chemokines in bacterial pneumonia

1996 • 159 citations

Mast cells of psoriatic and atopic dermatitis skin are positive for TNF-α and their degranulation is associated with expression of ICAM-1 in the epidermis

1998 • 146 citations

In Activated Mast Cells, IL-1 Up-Regulates the Production of Several Th2-Related Cytokines Including IL-9

2000 • 143 citations

The Immunopathology of Psoriasis

1996 • 135 citations

Cytokine networks in the skin.

1995 • 133 citations

Mast cell-dependent amplification of an immunologically nonspecific inflammatory response. Mast cells are required for the full expression of cutaneous acute inflammation induced by phorbol 12-myristate 13-acetate.

1988 • 127 citations

Defective elicitation of delayed-type hypersensitivity in W/Wv and SI/SId mast cell-deficient mice.

1983 • 124 citations

TNF-alpha and IL-1 sequentially induce endothelial ICAM-1 and VCAM-1 expression in MRL/lpr lupus-prone mice.

1999 • 123 citations

Unequivocal Delayed Hypersensitivity in Mast Cell-Deficient and Beige Mice

1984 • 121 citations

Skin innate immune system in psoriasis: friend or foe?

1999 • 121 citations

Macrophage Inflammatory Protein-2 Is Required for Neutrophil Passage Across the Epithelial Barrier of the Infected Urinary Tract

1999 • 118 citations

Immunology of Reactive Arthritides

1995 • 110 citations

Induction and enhancement of Fc(epsilon)RI-dependent mast cell degranulation following coculture with activated T cells: dependency on ICAM-1- and leukocyte function-associated antigen (LFA)-1-mediated heterotypic aggregation.

1998 • 109 citations

TNF-α and IL-1 Sequentially Induce Endothelial ICAM-1 and VCAM-1 Expression in MRL/lprLupus-Prone Mice

1999 • 97 citations

Groα-mediated recruitment of neutrophils is required for elicitation of contact hypersensitivity

1999 • 87 citations

Required Early Complement Activation in Contact Sensitivity with Generation of Local C5-dependent Chemotactic Activity, and Late T Cell Interferon γ: A Possible Initiating Role of B Cells

1997 • 84 citations

Induction and Enhancement of FcεRI-Dependent Mast Cell Degranulation Following Coculture with Activated T Cells: Dependency on ICAM-1- and Leukocyte Function-Associated Antigen (LFA)-1-Mediated Heterotypic Aggregation

1998 • 83 citations

Regulation of early peritoneal neutrophil migration by macrophage inflammatory protein-2 and mast cells in experimental peritonitis

1999 • 79 citations

Cytokine Gene Expression during the Elicitation Phase of Contact Sensitivity: Regulation By Endogenous IL-4

1997 • 76 citations

Cytokine Networks in the Skin

1995 • 68 citations

Multifunctional Cytokine Expression by Human Mast Cells: Regulation by T Cell Membrane Contact and Glucocorticoids

1997 • 65 citations

Arthritis and mast cell activation

1990 • 64 citations

Intralesional Cytokines in Chronic Oxazolone-Induced Contact Sensitivity Suggest Roles for Tumor Necrosis Factor α and Interleukin-4

1998 • 63 citations

TGFβ1 and TNFα Secreted by Mast Cells Stimulated via the FcϵRI Activate Fibroblasts for High-Level Production of Monocyte Chemoattractant Protein-1 (MCP-1)

2000 • 36 citations

Solution Structure of Murine Macrophage Inflammatory Protein-2^,

1998 • 31 citations

Schistosoma mansoni infection in mice augments the capacity for interleukin 3 (IL-3) and IL-9 production and concurrently enlarges progenitor pools for mast cells and granulocytes-macrophages

1996 • 25 citations

FcεRI-induced Cytokine Production and Gene Expression

1997 • 13 citations

Differential Cytokine and Chemokine Production Characterizes Experimental Autoimmune Meningitis and Experimental Autoimmune Encephalomyelitis

2000 • 9 citations