Inhibition of Allergic Contact Dermatitis to DNCB But Not to Oxazolone in Interleukin-4-Deficient Mice

Generation and Analysis of Interleukin-4 Deficient Mice

1991 • 1,266 citations

Disruption of the murine IL-4 gene blocks Th2 cytokine responses

1993 • 1,197 citations

Heterogeneity of Cytokine Secretion Patterns and Functions of Helper T Cells

1989 • 1,122 citations

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones.

1987 • 966 citations

Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

1974 • 572 citations

Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance.

1993 • 526 citations

T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells.

1996 • 398 citations

High Frequency of IL-4–Producing CD4+ Allergen-Specific T Lymphocytes in Atopic Dermatitis Lesional Skin

1991 • 397 citations

Development and validation of an alternative dermal sensitization test: The mouse ear swelling test (MEST)

1986 • 384 citations

Resistance to fever induction and impaired acute-phase response in interleukin-1β-deficient mice

1995 • 365 citations

TH2 cells in systemic autoimmunity: insights from allogeneic diseases and chemically-induced autoimmunity

1991 • 365 citations

Roles of CD4+ and CD8+ T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion.

1990 • 315 citations

IL-4 acts synergistically with IL-1 beta to promote lymphocyte adhesion to microvascular endothelium by induction of vascular cell adhesion molecule-1.

1990 • 286 citations

Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses.

1995 • 243 citations

Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.

1996 • 241 citations

Cytokine Induction in Human Epidermal Kerationocytes Exposed to Contact Irritants and Its Relation to Chemical-Induced Inflammation in Mouse Skin

1994 • 213 citations

Regulation of contact hypersensitivity by interleukin 10.

1994 • 168 citations

Constitutive Expression of Interleukin (IL)-4 In Vivo Causes Autoimmune-type Disorders in Mice

1997 • 151 citations

Th2 cells mediate IL-4-dependent local tissue inflammation.

1993 • 140 citations

Regulation of alloreactivity in vivo by IL-4 and the soluble IL-4 receptor.

1991 • 109 citations

Cultured Epidermal Langerhans Cells Activate Effector T Cells for Contact Sensitivity

1990 • 105 citations

Anti-inflammatory action of IL-4. Negative regulation of contact sensitivity to trinitrochlorobenzene.

1992 • 80 citations

Cytokine Gene Expression during the Elicitation Phase of Contact Sensitivity: Regulation By Endogenous IL-4

1997 • 76 citations

Interleukin-4 is a critical cytokine in contact sensitivity.

1995 • 71 citations

In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity

1985 • 59 citations

Diminished Contact Hypersensitivity Response in IL‐4 Deficient Mice at a Late Phase of the Elicitation Reaction

1997 • 58 citations

Genetic control of contact sensitivity in mice: Effect ofH-2 and nonH-2 loci

1974 • 56 citations

Differential Patterns of Epidermal Leukocyte Infiltration in Patch Test Reactions to Structurally Unrelated Chemical Irritants

1993 • 55 citations

IL-4 is essential for the systemic transfer of delayed hypersensitivity by T cell lines. Role of gamma/delta cells.

1994 • 52 citations

Different pathways in irritant contact eczema?

1996 • 46 citations

L3T4 (CD4+) cells that mediate contact sensitivity to trinitrochlorobenzene express I-A determinants

1991 • 43 citations

Tissue-specific expression of interleukin-4 induces extracellular matrix accumulation and extravasation of B cells.

1997 • 36 citations

Interleukin 4 and Tumour Necrosis Factor α Induce Different Adhesion Pathways in Endothelial Cells for the Binding of Peripheral Blood Lymphocytes

1992 • 18 citations

The anti-tumour and proinflammatory actions of IL4

1993 • 16 citations