Human T cell subset commitment determined by the intrinsic property of antigen: the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more IL-4 and less IFN-γ

Functional diversity of helper T lymphocytes

1996 • 4,512 citations

Determination of lymphocyte division by flow cytometry

1994 • 1,712 citations

Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines

1995 • 686 citations

Determination of antigen-specific memory/effector CD4+ T cell frequencies by flow cytometry: evidence for a novel, antigen-specific homeostatic mechanism in HIV-associated immunodeficiency.

1997 • 560 citations

Mite faeces are a major source of house dust allergens

1981 • 547 citations

Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies

1995 • 473 citations

Proteolytic Cleavage of CD25, the α Subunit of the Human T Cell Interleukin 2 Receptor, by Der p 1, a Major Mite Allergen with Cysteine Protease Activity

1998 • 254 citations

T cell activation-inducing epitopes of the house dust mite allergen Der p I. Proliferation and lymphokine production patterns by Der p I-specific CD4+ T cell clones.

1992 • 244 citations

The Cysteine Protease Activity of the Major Dust Mite Allergen Der P 1 Selectively Enhances the Immunoglobulin E Antibody Response

1999 • 211 citations

A mite subversive: cleavage of CD23 and CD25 by Der p 1 enhances allergenicity

1998 • 182 citations

Up-regulation of interleukin 4/B-cell stimulatory factor 1 receptor expression.

1988 • 145 citations

Expression and kinetics of cytokines determined by intracellular staining using flow cytometry

1999 • 108 citations

A sensitive fluorescent assay for measuring the cysteine protease activity of Der p 1, a major allergen from the dust mite Dermatophagoides pteronyssinus

1998 • 52 citations

House Dust Mite-Responsive Human T Cells Require both Interleukin 2 (IL2) and Interleukin 4 for Optimal Proliferation, Whereas IL2 Alone Is Sufficient for Proliferation of Tetanus Toxoid-Responsive T Cells

1994 • 7 citations