Regulation of BMP activity and range in Drosophila wing development

The Decapentaplegic morphogen gradient: from pattern formation to growth regulation

2007 • 377 citations

On the mechanism of wing size determination in fly development

2007 • 371 citations

Dynamics of Dpp Signaling and Proliferation Control

2011 • 355 citations

Shaping Morphogen Gradients by Proteoglycans

2009 • 338 citations

The Drosophila BMP Type II Receptor Wishful Thinking Regulates Neuromuscular Synapse Morphology and Function

2002 • 330 citations

Positional information revisited

1989 • 322 citations

Type IV collagens regulate BMP signalling in Drosophila

2008 • 315 citations

Drosophila Dpp Morphogen Movement Is Independent of Dynamin-Mediated Endocytosis but Regulated by the Glypican Members of Heparan Sulfate Proteoglycans

2004 • 297 citations

Wing Vein Patterning in Drosophila and the Analysis of Intercellular Signaling

2007 • 249 citations

Dally regulates Dpp morphogen gradient formation in theDrosophilawing

2003 • 223 citations

Regulation of Cell Proliferation by a Morphogen Gradient

2005 • 209 citations

The extracellular regulation of bone morphogenetic protein signaling

2009 • 199 citations

Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface

2007 • 190 citations

Model for the regulation of size in the wing imaginal disc of Drosophila

2006 • 182 citations

LIS1 and dynein motor function in neuronal migration and development

2001 • 169 citations

Regulation of self-renewal and differentiation by the intestinal stem cell niche

2011 • 166 citations

The BMP-Binding Protein Crossveinless 2 Is a Short-Range, Concentration-Dependent, Biphasic Modulator of BMP Signaling in Drosophila

2008 • 163 citations

TGF-β/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing

1998 • 156 citations

Hox Control of Organ Size by Regulation of Morphogen Production and Mobility

2006 • 154 citations

A Feed-Forward Circuit Linking Wingless, Fat-Dachsous Signaling, and the Warts-Hippo Pathway to Drosophila Wing Growth

2010 • 148 citations

Cooperative Regulation of Growth by Yorkie and Mad through bantam

2011 • 147 citations

Drosophila glypicans regulate the germline stem cell niche

2009 • 144 citations

Control of Dpp morphogen signalling by a secreted feedback regulator

2010 • 136 citations

The glypican Dally is required in the niche for the maintenance of germline stem cells and short-range BMP signaling in theDrosophilaovary

2009 • 136 citations

The Fused/Smurf Complex Controls the Fate of Drosophila Germline Stem Cells by Generating a Gradient BMP Response

2010 • 131 citations

Genetics of morphogen gradients

2001 • 129 citations

Dpp Signaling Activity Requires Pentagone to Scale with Tissue Size in the Growing Drosophila Wing Imaginal Disc

2011 • 122 citations

Expansion-Repression Mechanism for Scaling the Dpp Activation Gradient in Drosophila Wing Imaginal Discs

2011 • 121 citations

Heparan Sulfate Acts as a Bone Morphogenetic Protein Coreceptor by Facilitating Ligand-induced Receptor Hetero-oligomerization

2010 • 110 citations

The evolution of dorsal–ventral patterning mechanisms in insects

2011 • 106 citations

The BMP signaling pathway at the Drosophila neuromuscular junction and its links to neurodegenerative diseases

2010 • 98 citations

A conserved activation element in BMP signaling during Drosophila development

2009 • 97 citations

Mechanisms of Growth and Homeostasis in the Drosophila Wing

2009 • 96 citations

Dpp signaling promotes the cuboidal-to-columnar shape transition of Drosophila wing disc epithelia by regulating Rho1

2009 • 95 citations

Organism-Scale Modeling of Early Drosophila Patterning via Bone Morphogenetic Proteins

2010 • 90 citations

A presynaptic endosomal trafficking pathway controls synaptic growth signaling

2011 • 90 citations

The Measure of Success: Constraints, Objectives, and Tradeoffs in Morphogen-mediated Patterning

2009 • 86 citations

Decoding the quantitative nature of TGF-β/Smad signaling

2008 • 83 citations

Dpp and Gbb exhibit different effective ranges in the establishment of the BMP activity gradient critical for Drosophila wing patterning

2006 • 82 citations

Formation of the Long Range Dpp Morphogen Gradient

2011 • 80 citations

Novel Contact-dependent Bone Morphogenetic Protein (BMP) Signaling Mediated by Heparan Sulfate Proteoglycans

2011 • 77 citations

Antagonistic Growth Regulation by Dpp and Fat Drives Uniform Cell Proliferation

2011 • 74 citations

The Drosophila DPP signal is produced by cleavage of its proprotein at evolutionary diversified furin-recognition sites

2009 • 64 citations

Connecting Hh, Dpp and EGF signalling in patterning of theDrosophilawing; the pivotal role ofcollier/knotin the AP organiser

2002 • 63 citations

Hox control of morphogen mobility and organ development through regulation of glypican expression

2006 • 59 citations

Smad inhibition by the Ste20 kinase Misshapen

2011 • 57 citations

Dual function of theDrosophilaAlk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc

2006 • 57 citations

Cease and desist: modulating short‐range Dpp signalling in the stem‐cell niche

2011 • 56 citations

Mad Is Required for Wingless Signaling in Wing Development and Segment Patterning in Drosophila

2009 • 49 citations

The Decapentaplegic morphogen gradient: a precise definition

2008 • 48 citations

Selector and signalling molecules cooperate in organ patterning

2002 • 47 citations

Feedback regulation ofDrosophilaBMP signaling by the novel extracellular protein Larval Translucida

2011 • 41 citations

Shaping BMP Morphogen Gradients through Enzyme-Substrate Interactions

2011 • 41 citations

Analysis of dynamic morphogen scale invariance

2009 • 40 citations

Pattern formation by dynamically interacting network motifs

2009 • 39 citations

SMAD signaling drives heart and muscle dysfunction in a Drosophila model of muscular dystrophy

2010 • 37 citations

Robustness of the Dpp morphogen activity gradient depends on negative feedback regulation by the inhibitory Smad, Dad

2011 • 35 citations

Regulation of Dpp activity by tissue-specific cleavage of an upstream site within the prodomain

2010 • 33 citations

Specificity of the inhibitory effects of Dad on TGF‐β family type I receptors, Thickveins, Saxophone, and Baboon in Drosophila

2008 • 32 citations

Lissencephaly-1 controls germline stem cell self-renewal through modulating bone morphogenetic protein signaling and niche adhesion

2010 • 28 citations

Morphogens, nutrients, and the basis of organ scaling

2011 • 25 citations

The interaction between two TGF-β type I receptors plays important roles in ligand binding, SMAD activation, and gradient formation

2010 • 25 citations

Sulfated is a negative feedback regulator of wingless in Drosophila

2011 • 24 citations

Drosophila Smad2 Opposes Mad Signaling during Wing Vein Development

2010 • 23 citations

BMP signaling dynamics in the follicle cells of multiple Drosophila species

2011 • 23 citations

Position matters: Variability in the spatial pattern of BMP modulators generates functional diversity

2011 • 19 citations

The Effects of Weak Genetic Perturbations on the Transcriptome of the Wing Imaginal Disc and Its Association With Wing Shape in Drosophila melanogaster

2011 • 7 citations

Deleted Work

1955 • 0 citations