Sulfated is a negative feedback regulator of wingless in Drosophila

Mutations affecting segment number and polarity in Drosophila

1980 • 4,280 citations

Functions of Cell Surface Heparan Sulfate Proteoglycans

1999 • 2,660 citations

Analysis of genetic mosaics in developing and adult Drosophila tissues

1993 • 2,029 citations

MECHANISMS OF WNT SIGNALING IN DEVELOPMENT

1998 • 2,028 citations

Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate

2002 • 1,437 citations

Spatiotemporal Rescue of Memory Dysfunction in Drosophila

2003 • 1,253 citations

Armadillo Coactivates Transcription Driven by the Product of the Drosophila Segment Polarity Gene dTCF

1997 • 1,201 citations

Organizing activity of wingless protein in Drosophila

1993 • 852 citations

TheDrosophilamushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells

1997 • 783 citations

Morphogen gradient interpretation

2001 • 738 citations

Direct and Long-Range Action of a Wingless Morphogen Gradient

1996 • 736 citations

Specificities of heparan sulphate proteoglycans in developmental processes

2000 • 706 citations

Spatiotemporal Gene Expression Targeting with the TARGET and Gene-Switch Systems in Drosophila

2004 • 682 citations

Functions of heparan sulfate proteoglycans in cell signaling during development

2004 • 659 citations

Morphogens, Compartments, and Pattern: Lessons from Drosophila?

1996 • 559 citations

Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling

1999 • 474 citations

Regulation of Wnt Signaling and Embryo Patterning by an Extracellular Sulfatase

2001 • 462 citations

Morphogens, their identification and regulation

2004 • 437 citations

Wingless gradient formation in the Drosophila wing

2000 • 437 citations

QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling

2003 • 424 citations

Long-range action of Wingless organizes the dorsal-ventral axis of the Drosophila wing

1997 • 416 citations

Cloning and Characterization of Two Extracellular Heparin-degrading Endosulfatases in Mice and Humans

2002 • 404 citations

The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

1999 • 393 citations

Site-Specific Recombination Between Homologous Chromosomes in Drosophila

1991 • 389 citations

Heparan sulfate proteoglycans are critical for the organization of the extracellular distribution of Wingless

2001 • 370 citations

Pattern formation in a secondary field: a hierarchy of regulatory genes subdivides the developing Drosophila wing disc into discrete subregions

1993 • 292 citations

Negative regulation of Armadillo, a Wingless effector in Drosophila

1997 • 285 citations

The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways

1995 • 275 citations

ThreeDrosophilaEXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans

2003 • 274 citations

Axis specification in the developing Drosophila appendage: The role of wingless, decapentaplegic, and the homeobox gene aristaless

1993 • 271 citations

A wingless -Dependent Polar Coordinate System in Drosophila Imaginal Discs

1993 • 266 citations

HSPG Modification by the Secreted Enzyme Notum Shapes the Wingless Morphogen Gradient

2002 • 238 citations

Drosophilaglypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process

2004 • 237 citations

wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development

1993 • 234 citations

Distinct and collaborative roles ofDrosophilaEXT family proteins in morphogen signalling and gradient formation

2004 • 228 citations

Abrogation of heparan sulfate synthesis inDrosophiladisrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways

2004 • 221 citations

Drosophilaglypicans Dally and Dally-like shape the extracellular Wingless morphogen gradient in the wing disc

2005 • 216 citations

Opposing Activities of Dally-like Glypican at High and Low Levels of Wingless Morphogen Activity

2004 • 213 citations

Homeotic genes and positional signalling in the Drosophila viscera

1994 • 180 citations

pygopusencodes a nuclear protein essential for Wingless/Wnt signaling

2002 • 179 citations

Spatial Regulation of Wingless Morphogen Distribution and Signaling by Dally-like Protein

2004 • 164 citations

Glypicans shunt the Wingless signal between local signalling and further transport

2005 • 148 citations

Substrate Specificity and Domain Functions of Extracellular Heparan Sulfate 6-O-Endosulfatases, QSulf1 and QSulf2

2005 • 145 citations

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity

2006 • 125 citations

Wingful, an extracellular feedback inhibitor of Wingless

2002 • 121 citations

The Wingless morphogen gradient is established by the cooperative action of Frizzled and Heparan Sulfate Proteoglycan receptors

2004 • 119 citations

The Core Protein of Glypican Dally-Like Determines Its Biphasic Activity in Wingless Morphogen Signaling

2009 • 107 citations

Regulation of dally, an Integral Membrane Proteoglycan, and Its Function during Adult Sensory Organ Formation of Drosophila

2001 • 70 citations

On the role of glypicans in the process of morphogen gradient formation

2006 • 63 citations