Back to search

Dpp and Gbb exhibit different effective ranges in the establishment of the BMP activity gradient critical for Drosophila wing patterning

Data up to Jan 2025

Published2006
Citations82
References69

Total Citations Per Year

Abstract

References (69)

The chemical basis of morphogenesis

1952 • 11,233 citations

Positional information and the spatial pattern of cellular differentiation

1969 • 2,957 citations

Analysis of genetic mosaics in developing and adult Drosophila tissues

1993 • 2,029 citations

Drosophila — A Practical Approach

1987 • 1,888 citations

Direct and Long-Range Action of a DPP Morphogen Gradient

1996 • 896 citations

Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing

1996 • 629 citations

Gradient Formation of the TGF-β Homolog Dpp

2000 • 606 citations

Human Bone Morphogenetic Protein 2 Contains a Heparin‐Binding Site which Modifies Its Biological Activity

1996 • 555 citations

Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing

1995 • 489 citations

Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb

1994 • 465 citations

Dpp Gradient Formation in the Drosophila Wing Imaginal Disc

2000 • 453 citations

Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian

1999 • 413 citations

Do Morphogen Gradients Arise by Diffusion?

2002 • 403 citations

Hedgehog Creates a Gradient of DPP Activity in Drosophila Wing Imaginal Discs

2000 • 402 citations

Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster

1982 • 345 citations

Heterodimeric Bone Morphogenetic Proteins Show Enhanced ActivityIn VitroandIn Vivo

1996 • 335 citations

An extensive 3′ cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-β family in Drosophila

1991 • 330 citations

The zebrafish Nodal signal Squint functions as a morphogen

2001 • 328 citations

Drosophila Dpp Morphogen Movement Is Independent of Dynamin-Mediated Endocytosis but Regulated by the Glypican Members of Heparan Sulfate Proteoglycans

2004 • 297 citations

Facilitated Transport of a Dpp/Scw Heterodimer by Sog/Tsg Leads to Robust Patterning of the Drosophila Blastoderm Embryo

2005 • 291 citations

Transducing the Dpp Morphogen Gradient in the Wing of Drosophila

1999 • 280 citations

Equivalent genetic roles for bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation

2000 • 269 citations

Rapid preparation of a panel of polyclonal antibodies to Drosophila segmentation proteins

1998 • 266 citations

Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing

1996 • 264 citations

Sulfated Polysaccharides Enhance the Biological Activities of Bone Morphogenetic Proteins

2003 • 262 citations

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

1994 • 254 citations

Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements.

1990 • 250 citations

BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb

2001 • 242 citations

brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes

1999 • 232 citations

Regulation of Cell Proliferation by a Morphogen Gradient

2005 • 209 citations

Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway

2000 • 208 citations

Spatial bistability of Dpp–receptor interactions during Drosophila dorsal–ventral patterning

2005 • 207 citations

Control of the Gene optomotor-blind in Drosophila Wing Development by decapentaplegic and wingless

1996 • 206 citations

Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc

1998 • 202 citations

Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo

2000 • 202 citations

Molecular organization of the decapentaplegic gene in Drosophila melanogaster.

1990 • 201 citations

Conversion of an Extracellular Dpp/BMP Morphogen Gradient into an Inverse Transcriptional Gradient

2003 • 181 citations

Mechanisms for Positional Signalling by Morphogen Transport: a Theoretical Study

1998 • 181 citations

A characterization of the effects of Dpp signaling on cell growth and proliferation in theDrosophilawing

2002 • 180 citations

Action Range of BMP Is Defined by Its N-Terminal Basic Amino Acid Core

2002 • 175 citations

Wing formation in Drosophila melanogaster requires decapentaplegic gene function along the anterior-posterior compartment boundary

1990 • 170 citations

TGF-β/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing

1998 • 156 citations

Expression and function of decapentaplegic and thick veins during the differentiation of the veins in the Drosophila wing

1997 • 154 citations

Mesoderm Induction by BMP-4 and -7 Heterodimers

1997 • 147 citations

The decapentaplegic gene: a TGF-β homologue controlling pattern formation in Drosophila

1989 • 144 citations

The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor

2001 • 131 citations

Genetics of morphogen gradients

2001 • 129 citations

The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing

1997 • 127 citations

Morphogen gradients: new insights from DPP

1999 • 116 citations

SHORTVEIN, A NEW COMPONENT OF THE DECAPENTAPLEGIC GENE COMPLEX IN DROSOPHILA MELANOGASTER

1985 • 114 citations

Boundaries in the Drosophila wing imaginal disc organize vein-specific genetic programs

1998 • 106 citations

Morphogen gradients, positional information, and Xenopus: Interplay of theory and experiment

2002 • 101 citations

Thebrinkergradient controls wing growth inDrosophila

2004 • 100 citations

Nodal Stability Determines Signaling Range

2005 • 98 citations

Function of the spalt/spalt-related gene complex in positioning the veins in the Drosophila wing

2000 • 95 citations

Context-dependent relationships between the BMPsgbbanddppduring development of theDrosophilawing imaginal disk

2001 • 89 citations

Lumenal Transmission of Decapentaplegic in Drosophila Imaginal Discs

2002 • 87 citations

The knirps and knirps-related genes organize development of the second wing vein in Drosophila

1998 • 80 citations

Repression of Dpp Targets by Binding of Brinker to Mad Sites

2001 • 76 citations

Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing

1997 • 75 citations

brinkerandoptomotor-blindact coordinately to initiate development of the L5 wing vein primordium inDrosophila

2004 • 72 citations

Connecting Hh, Dpp and EGF signalling in patterning of theDrosophilawing; the pivotal role ofcollier/knotin the AP organiser

2002 • 63 citations

Dual function of theDrosophilaAlk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc

2006 • 57 citations

Activation of theknirpslocus links patterning to morphogenesis of the second wing vein inDrosophila

2002 • 49 citations

Comparison of Ectopic Osteoinductionin Vivoby Recombinant Human BMP-2 and Recombinant Xenopus BMP-4/7 Heterodimer

1997 • 36 citations

Surviving Drosophila eye development: integrating cell death with differentiation during formation of a neural structure

1999 • 35 citations

Molecular Lesions Associated With Alleles of decapentuplegic Identify Residues Necessary for TGF-β/BMP Cell Signaling in Drosophila melanogaster

1996 • 32 citations

BMP Signalling: Synergy and Feedback Create a Step Gradient

2005 • 24 citations

Analysis of the shortvein cis-regulatory region of thedecapentaplegic gene ofDrosophila melanogaster

2005 • 11 citations

Cited By (0)

Loading...
Dpp and Gbb exhibit different effective ranges in the establishment of the BMP activity… (2006) – Developmental Biology | Metascience Observatory Explorer