Dpp and Gbb exhibit different effective ranges in the establishment of the BMP activity gradient critical for Drosophila wing patterning
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References (69)
The chemical basis of morphogenesis
1952 • 11,233 citations
Positional information and the spatial pattern of cellular differentiation
1969 • 2,957 citations
Analysis of genetic mosaics in developing and adult Drosophila tissues
1993 • 2,029 citations
Drosophila — A Practical Approach
1987 • 1,888 citations
Direct and Long-Range Action of a DPP Morphogen Gradient
1996 • 896 citations
Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing
1996 • 629 citations
Gradient Formation of the TGF-β Homolog Dpp
2000 • 606 citations
Human Bone Morphogenetic Protein 2 Contains a Heparin‐Binding Site which Modifies Its Biological Activity
1996 • 555 citations
Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing
1995 • 489 citations
Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb
1994 • 465 citations
Dpp Gradient Formation in the Drosophila Wing Imaginal Disc
2000 • 453 citations
Processing of the Notch Ligand Delta by the Metalloprotease Kuzbanian
1999 • 413 citations
Do Morphogen Gradients Arise by Diffusion?
2002 • 403 citations
Hedgehog Creates a Gradient of DPP Activity in Drosophila Wing Imaginal Discs
2000 • 402 citations
Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster
1982 • 345 citations
Heterodimeric Bone Morphogenetic Proteins Show Enhanced ActivityIn VitroandIn Vivo
1996 • 335 citations
An extensive 3′ cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-β family in Drosophila
1991 • 330 citations
The zebrafish Nodal signal Squint functions as a morphogen
2001 • 328 citations
Drosophila Dpp Morphogen Movement Is Independent of Dynamin-Mediated Endocytosis but Regulated by the Glypican Members of Heparan Sulfate Proteoglycans
2004 • 297 citations
Facilitated Transport of a Dpp/Scw Heterodimer by Sog/Tsg Leads to Robust Patterning of the Drosophila Blastoderm Embryo
2005 • 291 citations
Transducing the Dpp Morphogen Gradient in the Wing of Drosophila
1999 • 280 citations
Equivalent genetic roles for bmp7/snailhouse and bmp2b/swirl in dorsoventral pattern formation
2000 • 269 citations
Rapid preparation of a panel of polyclonal antibodies to Drosophila segmentation proteins
1998 • 266 citations
Dpp receptors are autonomously required for cell proliferation in the entire developing Drosophila wing
1996 • 264 citations
Sulfated Polysaccharides Enhance the Biological Activities of Bone Morphogenetic Proteins
2003 • 262 citations
Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor
1994 • 254 citations
Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements.
1990 • 250 citations
BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb
2001 • 242 citations
brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes
1999 • 232 citations
Regulation of Cell Proliferation by a Morphogen Gradient
2005 • 209 citations
Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway
2000 • 208 citations
Spatial bistability of Dpp–receptor interactions during Drosophila dorsal–ventral patterning
2005 • 207 citations
Control of the Gene optomotor-blind in Drosophila Wing Development by decapentaplegic and wingless
1996 • 206 citations
Dpp receptor levels contribute to shaping the Dpp morphogen gradient in the Drosophila wing imaginal disc
1998 • 202 citations
Essential role of Bmp7 (snailhouse) and its prodomain in dorsoventral patterning of the zebrafish embryo
2000 • 202 citations
Molecular organization of the decapentaplegic gene in Drosophila melanogaster.
1990 • 201 citations
Conversion of an Extracellular Dpp/BMP Morphogen Gradient into an Inverse Transcriptional Gradient
2003 • 181 citations
Mechanisms for Positional Signalling by Morphogen Transport: a Theoretical Study
1998 • 181 citations
A characterization of the effects of Dpp signaling on cell growth and proliferation in theDrosophilawing
2002 • 180 citations
Action Range of BMP Is Defined by Its N-Terminal Basic Amino Acid Core
2002 • 175 citations
Wing formation in Drosophila melanogaster requires decapentaplegic gene function along the anterior-posterior compartment boundary
1990 • 170 citations
TGF-β/BMP superfamily members, Gbb-60A and Dpp, cooperate to provide pattern information and establish cell identity in the Drosophila wing
1998 • 156 citations
Expression and function of decapentaplegic and thick veins during the differentiation of the veins in the Drosophila wing
1997 • 154 citations
Mesoderm Induction by BMP-4 and -7 Heterodimers
1997 • 147 citations
The decapentaplegic gene: a TGF-β homologue controlling pattern formation in Drosophila
1989 • 144 citations
The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor
2001 • 131 citations
Genetics of morphogen gradients
2001 • 129 citations
The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing
1997 • 127 citations
Morphogen gradients: new insights from DPP
1999 • 116 citations
SHORTVEIN, A NEW COMPONENT OF THE DECAPENTAPLEGIC GENE COMPLEX IN DROSOPHILA MELANOGASTER
1985 • 114 citations
Boundaries in the Drosophila wing imaginal disc organize vein-specific genetic programs
1998 • 106 citations
Morphogen gradients, positional information, and Xenopus: Interplay of theory and experiment
2002 • 101 citations
Thebrinkergradient controls wing growth inDrosophila
2004 • 100 citations
Nodal Stability Determines Signaling Range
2005 • 98 citations
Function of the spalt/spalt-related gene complex in positioning the veins in the Drosophila wing
2000 • 95 citations
Context-dependent relationships between the BMPsgbbanddppduring development of theDrosophilawing imaginal disk
2001 • 89 citations
Lumenal Transmission of Decapentaplegic in Drosophila Imaginal Discs
2002 • 87 citations
The knirps and knirps-related genes organize development of the second wing vein in Drosophila
1998 • 80 citations
Repression of Dpp Targets by Binding of Brinker to Mad Sites
2001 • 76 citations
Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing
1997 • 75 citations
brinkerandoptomotor-blindact coordinately to initiate development of the L5 wing vein primordium inDrosophila
2004 • 72 citations
Connecting Hh, Dpp and EGF signalling in patterning of theDrosophilawing; the pivotal role ofcollier/knotin the AP organiser
2002 • 63 citations
Dual function of theDrosophilaAlk1/Alk2 ortholog Saxophone shapes the Bmp activity gradient in the wing imaginal disc
2006 • 57 citations
Activation of theknirpslocus links patterning to morphogenesis of the second wing vein inDrosophila
2002 • 49 citations
Comparison of Ectopic Osteoinductionin Vivoby Recombinant Human BMP-2 and Recombinant Xenopus BMP-4/7 Heterodimer
1997 • 36 citations
Surviving Drosophila eye development: integrating cell death with differentiation during formation of a neural structure
1999 • 35 citations
Molecular Lesions Associated With Alleles of decapentuplegic Identify Residues Necessary for TGF-β/BMP Cell Signaling in Drosophila melanogaster
1996 • 32 citations
BMP Signalling: Synergy and Feedback Create a Step Gradient
2005 • 24 citations
Analysis of the shortvein cis-regulatory region of thedecapentaplegic gene ofDrosophila melanogaster
2005 • 11 citations