The Correlation of ATP-binding Cassette 1 mRNA Levels with Cholesterol Efflux from Various Cell Lines

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1978 • 6,494 citations

de la Chapelle, A.

1997 • 3,184 citations

The plasma lecithin:cholesterol acyltransferase reaction

1968 • 2,415 citations

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

1999 • 1,708 citations

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

1999 • 1,527 citations

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

1999 • 1,441 citations

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

1995 • 1,310 citations

Practical Methods for Plasma Lipoprotein Analysis1 1Work supported in part by the U.S. Atomic Energy Commission and by grants (HE06222 and FR00102) from the U.S. Public Health Service.

1968 • 1,255 citations

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

1998 • 980 citations

Mutations in the Sulfonylurea Receptor Gene in Familial Persistent Hyperinsulinemic Hypoglycemia of Infancy

1995 • 812 citations

Use of cyclodextrins for manipulating cellular cholesterol content

1997 • 735 citations

The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway

1999 • 732 citations

Scavenger Receptor BI Promotes High Density Lipoprotein-mediated Cellular Cholesterol Efflux

1997 • 694 citations

Phosphatidylcholine translocase: A physiological role for the mdr2 gene

1994 • 600 citations

An inventory of the human ABC proteins

1999 • 587 citations

High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

2000 • 543 citations

Cell cholesterol efflux: integration of old and new observations provides new insights

1999 • 502 citations

Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice

2000 • 477 citations

Cholesterol transport between cells and high-density lipoproteins

1991 • 451 citations

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease.

1995 • 416 citations

Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP

1998 • 343 citations

Structure of the Multidrug Resistance P-glycoprotein to 2.5 nm Resolution Determined by Electron Microscopy and Image Analysis

1997 • 341 citations

Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol.

1991 • 331 citations

Multiple physiological functions for multidrug transporter P-glycoprotein?

2000 • 305 citations

The 220-kDa Rim Protein of Retinal Rod Outer Segments Is a Member of the ABC Transporter Superfamily

1997 • 297 citations

Scavenger Receptor Class B Type I as a Mediator of Cellular Cholesterol Efflux to Lipoproteins and Phospholipid Acceptors

1998 • 291 citations

The intrinsic factor–vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein

1999 • 268 citations

Cloning of Two Novel ABC Transporters Mapping on Human Chromosome 9

1994 • 262 citations

Membrane topology distinguishes a subfamily of the ATP‐binding cassette (ABC) transporters

1997 • 237 citations

Decreased Reverse Cholesterol Transport from Tangier Disease Fibroblasts

1997 • 203 citations

Cyclic AMP Induces Apolipoprotein E Binding Activity and Promotes Cholesterol Efflux from a Macrophage Cell Line to Apolipoprotein Acceptors

1996 • 196 citations

Efflux of cellular cholesterol and phospholipid to lipid-free apolipoproteins and class A amphipathic peptides

1995 • 188 citations

Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol.

1994 • 187 citations

Mechanism of cholesterol efflux from cells. Effects of acceptor structure and concentration.

1982 • 184 citations

Reverse cholesterol transport: Physiology and pharmacology

1991 • 112 citations

Cholesterol efflux mediated by apolipoproteins is an active cellular process distinct from efflux mediated by passive diffusion

1997 • 111 citations

Cholesterol Metabolism and Efflux in Human THP-1 Macrophages

1998 • 107 citations

Induction of cellular cholesterol efflux to lipid-free apolipoprotein A-I by cAMP

1999 • 94 citations

Cellular cholesterol efflux. Role of cell membrane kinetic pools and interaction with apolipoproteins AI, AII, and Cs.

1992 • 92 citations

cAMP stimulates cholesteryl ester clearance to high density lipoproteins in J7774 macrophages.

1991 • 90 citations

Cholesterol quantitation by GLC: artifactual formation of short-chain steryl esters.

1996 • 83 citations

The High Density Lipoprotein- and Apolipoprotein A-I-Induced Mobilization of Cellular Cholesterol Is Impaired in Fibroblasts from Tangier Disease Subjects

1994 • 79 citations

Monensin and Brefeldin A Inhibit High Density Lipoprotein- mediated Cholesterol Efflux from Cholesterol-enriched Cells

1995 • 74 citations

Selective Inhibition of Free Apolipoprotein-Mediated Cellular Lipid Efflux by Probucol

1996 • 73 citations

Selective Down-Regulation by Protein Kinase C Inhibitors of Apolipoprotein-Mediated Cellular Cholesterol Efflux in Macrophages

1997 • 73 citations

Biphasic Increase in c-jun mRNA Is Required for Induction of AP-1-Mediated Gene Transcription: Differential Effects of Muscarinic and Thrombin Receptor Activation

1992 • 71 citations

Human ApoA-IV Overexpression in Transgenic Mice Induces cAMP-Stimulated Cholesterol Efflux From J774 Macrophages to Whole Serum

2000 • 64 citations

Apolipoprotein A-I promotes cholesterol release and apolipoprotein E recruitment from THP-1 macrophage-like foam cells

1999 • 62 citations

Reduction in apolipoprotein-mediated removal of cellular lipids by immortalization of human fibroblasts and its reversion by cAMP: lack of effect with Tangier disease cells

1999 • 47 citations

Incubation of acetylated low-density lipoprotein with cholesterol-rich dispersions enhances cholesterol uptake by macrophages

1987 • 46 citations

Plasma and fibroblasts of Tangier disease patients are disturbed in transferring phospholipids onto apolipoprotein A-I

1998 • 41 citations

The Biphasic mRNA Expression Pattern of Bovine Interleukin-8 inPasteurella haemolyticaLipopolysaccharide-Stimulated Alveolar Macrophages Is Primarily due to Tumor Necrosis Factor Alpha

1998 • 37 citations

Limited proteolysis of high density lipoprotein abolishes its interaction with cell-surface binding sites that promote cholesterol efflux

1997 • 36 citations

Reverse cholesterol transport

1991 • 34 citations

Involvement of a cellular surface factor(s) in lipid-free apolipoprotein-mediated cellular cholesterol efflux

1995 • 32 citations

ATP-binding cassette proteins as targets for drug discovery

1996 • 30 citations

Generation of Pre-β ₁ -HDL and Conversion Into α-HDL

1995 • 27 citations

Apolipoprotein AI Efficiently Binds to and Mediates Cholesterol and Phospholipid Efflux from Human but Not Rat Aortic Smooth Muscle Cells

1999 • 24 citations

Efflux of phospholipid from fibroblasts with normal and elevated levels of cholesterol

1991 • 24 citations