High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1

A Receptor-Mediated Pathway for Cholesterol Homeostasis

1986 • 5,638 citations

ABC Transporters: From Microorganisms to Man

1992 • 3,956 citations

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

1999 • 1,708 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

1999 • 1,527 citations

Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

1999 • 1,441 citations

THE TROMSØHEART-STUDY

1977 • 1,212 citations

Early incorporation of cell-derived cholesterol into pre-.beta.-migrating high-density lipoprotein

1988 • 643 citations

Immunomodulatory functions of surfactant

1997 • 589 citations

Plasma High-Density Lipoproteins

1978 • 504 citations

Cell cholesterol efflux: integration of old and new observations provides new insights

1999 • 502 citations

Molecular Cloning of the Human ATP-Binding Cassette Transporter 1 (hABC1): Evidence for Sterol-Dependent Regulation in Macrophages

1999 • 502 citations

Transport of lipids from Golgi to plasma membrane is defective in Tangier disease patients and Abc1-deficient mice

2000 • 477 citations

Defective removal of cellular cholesterol and phospholipids by apolipoprotein A-I in Tangier Disease.

1995 • 416 citations

Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels

1999 • 378 citations

Distribution and Functions of Lecithin: Cholesterol Acyltransferase and Cholesteryl Ester Transfer Protein in Plasma Lipoproteins

1989 • 282 citations

Cloning of Two Novel ABC Transporters Mapping on Human Chromosome 9

1994 • 262 citations

Lower Plasma Levels and Accelerated Clearance of High Density Lipoprotein (HDL) and Non-HDL Cholesterol in Scavenger Receptor Class B Type I Transgenic Mice

1999 • 227 citations

Clinical, biochemical, and genetic features in familial disorders of high density lipoprotein deficiency.

1984 • 177 citations

A high-density probe array sample preparation method using 10- to 100-fold fewer cells

1999 • 160 citations

Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in rats

1974 • 141 citations

The pathology of Tangier disease. A light and electron microscopic study.

1975 • 140 citations

ABC1, an ATP Binding Cassette Transporter Required for Phagocytosis of Apoptotic Cells, Generates a Regulated Anion Flux after Expression in Xenopus laevis Oocytes

1997 • 135 citations

ALPHA LIPOPROTEIN (HDL) CHOLESTEROL IN THE SERUM AND THE RISK OF CORONARY HEART DISEASE AND DEATH

1980 • 110 citations

Increased prebeta-HDL levels, cholesterol efflux, and LCAT-mediated esterification in mice expressing the human cholesteryl ester transfer protein (CETP) and human apolipoprotein A-I (apoA-I) transgenes.

1996 • 108 citations

Hyper- and hypo-responsiveness to dietary fat and cholesterol among inbred mice: searching for level and variability genes

1995 • 86 citations

Degradation of surfactant lipids and surfactant protein A by alveolar macrophages in vitro

1995 • 74 citations

Pulmonary Surfactant

1989 • 69 citations

A New Embryonic Stem Cell Line from DBA/1lacJ Mice Allows Genetic Modification in a Murine Model of Human Inflammation

1995 • 57 citations

Expression of human lecithin:cholesterol acyltransferase in transgenic mice: effects on cholesterol efflux, esterification, and transport

1997 • 55 citations

In vivo metabolism of proapolipoprotein A-I in Tangier disease.

1987 • 55 citations

Secretion of Lecithin:Cholesterol Acyltransferase by Brain Neuroglial Cell Lines

1999 • 19 citations

Lipids

1975 • 2 citations