Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 21,307 citations

The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid

1960 • 2,598 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

1981 • 1,325 citations

In vitro methods in cell-mediated and tumor immunity

1976 • 1,266 citations

High density lipoprotein metabolism.

1984 • 1,230 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts.

1976 • 1,032 citations

The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.

1980 • 727 citations

A molecular theory of lipid—protein interactions in the plasma lipoproteins

1974 • 725 citations

Early incorporation of cell-derived cholesterol into pre-.beta.-migrating high-density lipoprotein

1988 • 643 citations

Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins.

1979 • 545 citations

The role of the monocyte in atherogenesis: II. Migration of foam cells from atherosclerotic lesions.

1981 • 468 citations

Structural and Metabolic Heterogeneity of Rat Liver Glycerophosphatides

1968 • 458 citations

Isolation, characterization, and mapping to chromosome 19 of the human apolipoprotein E gene.

1985 • 352 citations

Role of the low density lipoprotein receptor in regulating the content of free and esterified cholesterol in human fibroblasts.

1975 • 317 citations

[32] Reconstitution of high-density lipoproteins

1986 • 316 citations

Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts.

1979 • 303 citations

Biochemical and genetic studies of the apoprotein E secreted by mouse macrophages and human monocytes.

1982 • 296 citations

Hydrolysis and excretion of cytoplasmic cholesteryl esters by macrophages: stimulation by high density lipoprotein and other agents

1980 • 279 citations

Regulation of high density lipoprotein receptor activity in cultured human skin fibroblasts and human arterial smooth muscle cells.

1983 • 276 citations

The role of apolipoprotein A-IV in reverse cholesterol transport studied with cultured cells and liposomes derived from an ether analog of phosphatidylcholine

1986 • 238 citations

Interstitial fluid lipoproteins.

1987 • 223 citations

The Structure of Human High Density Lipoprotein and the Levels of Apolipoprotein A-I in Plasma as Determined by Radioimmunoassay

1974 • 222 citations

Distribution of apolipoprotein A-IV in human plasma.

1985 • 217 citations

The effects of subfractions of high density lipoprotein on cholesterol efflux from cultured fibroblasts. Regulation of low density lipoprotein receptor activity.

1981 • 201 citations

Cholesterol content and sterol synthesis in human skin fibroblasts and rat aortic smooth muscle cells exposed to lipoprotein-depleted serum and high density apolipoprotein/phospholipid mixtures

1976 • 196 citations

Binding of high density lipoproteins to cell receptors promotes translocation of cholesterol from intracellular membranes to the cell surface.

1987 • 193 citations

Apolipoprotein A-I-containing lipoproteins with pre-beta electrophoretic mobility.

1985 • 189 citations

Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency.

1980 • 188 citations

Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters.

1987 • 152 citations

PHYLOGENIES CONSTRAINED BY THE CROSSOVER PROCESS AS ILLUSTRATED BY HUMAN HEMOGLOBINS AND A THIRTEEN-CYCLE, ELEVEN-AMINO-ACID REPEAT IN HUMAN APOLIPOPROTEIN A-I

1977 • 152 citations

Morphological characterization of the cholesteryl ester cycle in cultured mouse macrophage foam cells.

1983 • 145 citations

The removal of cholesterol from landschütz ascites cells by high-density apolipoprotein

1973 • 142 citations

Prebeta-migrating high density lipoprotein: quantitation in normal and hyperlipidemic plasma by solid phase radioimmunoassay following electrophoretic transfer.

1987 • 139 citations

Effect of lipid particle size on association of apolipoproteins with lipid.

1983 • 134 citations

The Lipids and Lipoproteins of Human Peripheral Lymph, with Observations on the Transport of Cholesterol from Plasma and Tissues into Lymph

1973 • 127 citations

Mechanism of the association of HDL3 with endothelial cells, smooth muscle cells, and fibroblasts. Evidence against the role of specific ligand and receptor proteins.

1984 • 126 citations

Cholesterol flux between cells and high density lipoprotein. Lack of relationship to specific binding of the lipoprotein to the cell surface.

1987 • 124 citations

Behavior of human apolipoprotein E in aqueous solutions and at interfaces.

1985 • 115 citations

The lipoprotein abnormality in Tangier disease: quantitation of A apoproteins.

1977 • 108 citations

High density lipoprotein stimulates sterol translocation between intracellular and plasma membrane pools in human monocyte-derived macrophages.

1989 • 103 citations

Characterization of dog peripheral lymph lipoproteins: the presence of a disc-shaped "nascent" high density lipoprotein.

1983 • 99 citations

The influence of cellular and lipoprotein cholesterol contents on the flux of cholesterol between fibroblasts and high density lipoprotein.

1988 • 90 citations

Studies on the rate of efflux of cholesterol from cultured human skin fibroblasts.

1981 • 87 citations

The Process of Dissolving Apolipoprotein A-I in an Aqueous Buffer1

1982 • 79 citations

Thermodynamics of lipid-protein interactions: interaction of apolipoprotein A-II from human plasma high-density lipoproteins with dimyristoylphosphatidylcholine

1981 • 68 citations

Stability of free apolipoprotein A-1 concentration in serum, and its measurement in normal and hyperlipidemic subjects.

1987 • 60 citations

Structure of the dimyristoylphosphatidylcholine vesicle and the complex formed by its interaction with apolipoprotein C-III: x-ray small angle scattering studies

1979 • 57 citations

Characterization of dog prenodal peripheral lymph lipoproteins. Evidence for the peripheral formation of lipoprotein-unassociated apoA-I with slow pre-beta electrophoretic mobility.

1988 • 55 citations

Human lymphedema fluid lipoproteins: particle size, cholesterol and apolipoprotein distributions, and electron microscopic structure.

1985 • 45 citations

Lecithin:cholesterol acyltransferase-mediated modification of discoidal peripheral lymph high density lipoproteins: possible mechanism of formation of cholesterol-induced high density lipoproteins (HDLc) in cholesterol-fed dogs.

1983 • 41 citations

The role of lysophosphatidylcholine and apolipoprotein A1 in the cholesterol-removing capacity of lipoprotein-deficient serum in tissue culture

1979 • 40 citations

Thermodynamics of lipid-protein association. The free energy of association of lecithin with reduced and carboxymethylated apolipoprotein A-II from human plasma high density lipoprotein.

1981 • 37 citations

Cell-surface binding sites for high density lipoproteins do not mediate efflux of cholesterol from human fibroblasts in tissue culture.

1988 • 36 citations

High-density lipoprotein-induced cholesterol efflux from arterial smooth muscle cell-derived foam cells: functional relationship of the cholesteryl ester cycle and eicosanoid biosynthesis

1990 • 32 citations

A Method for Direct Incorporation of Radiolabeled Cholesteryl Ester into Human Plasma Low-Density-Lipoproteins: Preparation of Tracer Substrate for Cholesteryl Ester Transfer Reaction between Lipoproteins1

1986 • 31 citations

The concentration of apolipoprotein A-II in human peripheral lymph

1989 • 29 citations

Contribution of alpha helix formation in human plasma apolipoproteins to their enthalpy of association with phospholipids.

1979 • 27 citations

Association of Apolipoprotein A-II with Egg Phosphatidylcholine Unilamellar Vesicles1

1984 • 12 citations