Cytotoxic T Cells

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions

1998 • 2,615 citations

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell

1998 • 2,373 citations

THE B7 FAMILY REVISITED

2005 • 2,239 citations

High-Dose Recombinant Interleukin 2 Therapy for Patients With Metastatic Melanoma: Analysis of 270 Patients Treated Between 1985 and 1993

1999 • 1,967 citations

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

1998 • 1,826 citations

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

2003 • 1,563 citations

Functional significance of the perforin/granzyme cell death pathway

2002 • 1,186 citations

Skewed maturation of memory HIV-specific CD8 T lymphocytes

2001 • 1,025 citations

Molecular and Functional Profiling of Memory CD8 T Cell Differentiation

2002 • 962 citations

Human tumor antigens recognized by T lymphocytes.

1996 • 860 citations

A listing of human tumor antigens recognized by T cells

2001 • 708 citations

Population Biology of Antigen Presentation by MHC Class I Molecules

1996 • 652 citations

Secretory lysosomes

2002 • 633 citations

BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes

1995 • 598 citations

The Telomerase Catalytic Subunit Is a Widely Expressed Tumor-Associated Antigen Recognized by Cytotoxic T Lymphocytes

1999 • 574 citations

T-cell repertoire diversity and clonal expansions in normal and clinical samples

1995 • 562 citations

Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases

2002 • 471 citations

A listing of human tumor antigens recognized by T cells: March 2004 update

2004 • 463 citations

Cancer Immunotherapy With Peptide-Based Vaccines: What Have We Achieved? Where Are We Going?

2002 • 400 citations

Immunologic Monitoring of Cancer Vaccine Therapy: Results of a Workshop Sponsored by the Society for Biological Therapy

2002 • 303 citations

Identification of a cytotoxic T lymphocyte response to the apoptosis inhibitor protein survivin in cancer patients.

2001 • 258 citations

Spontaneous cytotoxic T-cell responses against survivin-derived MHC class I-restricted T-cell epitopes in situ as well as ex vivo in cancer patients.

2001 • 258 citations

Cytotoxic T cell response against the chimeric p210 BCR-ABL protein in patients with chronic myelogenous leukemia.

1998 • 244 citations

Regulatory T Cells

2005 • 242 citations

Differentiation of Human CD8+ T Cells from a Memory to Memory/Effector Phenotype

2002 • 224 citations

Generation of survivin-specific CD8+ T effector cells by dendritic cells pulsed with protein or selected peptides.

2000 • 218 citations

Functional Analysis of Antigen-Specific T Lymphocytes by Serial Measurement of Gene Expression in Peripheral Blood Mononuclear Cells and Tumor Specimens

1999 • 206 citations

Detection and quantification of blood-derived CD8+ T lymphocytes secreting tumor necrosis factor α in response to HLA-A2.1-binding melanoma and viral peptide antigens

1996 • 179 citations

The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens

2003 • 177 citations

Regulation of Antigen Presentation and Cross-Presentation in the Dendritic Cell Network: Facts, Hypothesis, and Immunological Implications

2005 • 170 citations

Strategies for immunotherapy of cancer

2000 • 165 citations

The role of CD4+ and CD8+ T cells in contact hypersensitivity and allergic contact dermatitis.

2004 • 159 citations

Tumor antigens recognized by T lymphocytes

1997 • 153 citations

New insights into the pathogenesis of systemic sclerosis

2003 • 150 citations

The Human T Cell Receptor in Health and Disease

1992 • 149 citations

CD40 and Dendritic Cell Function

2003 • 146 citations

Dendritic cells: Immunological sentinels with a central role in health and disease

2000 • 145 citations

Protection against a nonimmunogenic mouse leukemia by an immunogenic variant obtained by mutagenesis.

1982 • 143 citations

Functional Dissociation Between Local and Systemic Immune Response During Anti-Melanoma Peptide Vaccination

1998 • 127 citations

Fas-Mediated Apoptosis

1996 • 118 citations

T‐cell recognition of melanoma‐associated antigens

2000 • 114 citations

T-cell recognition of melanoma-associated antigens

2000 • 102 citations

Phenotypic classification of human CD8⁺ T cells reflecting their function: inverse correlation between quantitative expression of CD27 and cytotoxic effector function

2004 • 101 citations

Cutting Edge: Dissociation Between Autoimmune Response and Clinical Disease After Vaccination with Dendritic Cells

2003 • 94 citations

Functional Heterogeneity of Vaccine-Induced CD8+ T Cells

2002 • 87 citations

Accumulation of Identical T Cells in Melanoma and Vitiligo-Like Leukoderma

1999 • 80 citations

The Noble Lectures in Immunology

1989 • 72 citations

Breaking tolerance to nickel

2005 • 69 citations

Lack of Epstein-Barr virus- and HIV-specific CD27− CD8+ T cells is associated with progression to viral disease in HIV-infection

2002 • 68 citations

4-1BB-ligand is regulated on human dendritic cells and induces the production of IL-12

2003 • 67 citations

Immunogenicity of Constitutively Active V599EBRaf

2004 • 66 citations

In Situ T Cell Responses Against Melanoma Comprise High Numbers of Locally Expanded T Cell Clonotypes

1999 • 64 citations

Immunoregulation of Allergic Contact Dermatitis

2004 • 62 citations

Initiation and regulation of CD8+T cells recognizing melanocytic antigens in the epidermis: Implications for the pathophysiology of vitiligo

2004 • 53 citations

Hypopigmentary Skin Disorders

2004 • 46 citations

Alternative antigen processing pathways in anti-infective immunity

1997 • 44 citations

Visual demonstration of hepatitis C virus-specific memory CD8+ T-cell expansion in patients with acute hepatitis C

2001 • 40 citations

Specific peptide-mediated immunity against established melanoma tumors with dendritic cells requires IL-2 and fetal calf serum-free cell culture

2002 • 40 citations

Vaccination of patients with solid tumours

2003 • 37 citations

T-cell-directed cancer vaccines: the melanoma model

2001 • 36 citations

Identification of a Human CD8+T Lymphocyte Neo-epitope Created by arasCodon 12 Mutation Which Is Restricted by the HLA-A2 Allele

1998 • 34 citations

Activation of preexisting T cell clones by targeted interleukin 2 therapy

1998 • 33 citations

Aggregation of Antigen-Specific T Cells at the Inoculation Site of Mature Dendritic Cells

2002 • 32 citations

Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens

1997 • 30 citations

The Nobel Lectures in Immunology The Nobel Prize for Physiology or Medicine, 1996 awarded to

1997 • 28 citations

CD8⁺ cytolytic T lymphocytes and the skin

1998 • 27 citations

Differential expression of CD28 and CD94 / NKG2 on T cells with identical TCR beta variable regions in primary melanoma and sentinel lymph node

2000 • 26 citations

Human lung cancer cells endogenously expressing mutant p53 process and present the mutant epitope and are lysed by mutant-specific cytotoxic T lymphocytes

1996 • 24 citations

Oligoclonal T-cell receptor usage of melanocyte differentiation antigen-reactive T cells in stage IV melanoma patients.

2001 • 24 citations

Differential Expression of Inhibitory or Activating CD94/NKG2 Subtypes on MART-1-Reactive T Cells in Vitiligo Versus Melanoma: A Case Report

2002 • 16 citations

Shift from Systemic to Site-Specific Memory by Tumor-Targeted IL-2

2004 • 15 citations

Hashimoto's thyroiditis is associated with peripheral lymphocyte activation in patients with systemic sclerosis.

2005 • 10 citations

Induction of experimental autoimmune thyroiditis by heat-denatured porcine thyroglobulin: a Tc1-mediated disease

1999 • 9 citations

Identical T-cell receptor transcripts in multiple melanoma metastases.

2002 • 7 citations

Immunological consequences of the sentinel lymph-node biopsy—lessons from a melanoma patient

2003 • 5 citations

Defining the Parameters Necessary for T-Cell Recognition of Ligands That Vary in Potency

2004 • 3 citations