Detection and quantification of blood-derived CD8+ T lymphocytes secreting tumor necrosis factor α in response to HLA-A2.1-binding melanoma and viral peptide antigens

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

1991 • 3,493 citations

A p16 ^INK4a -Insensitive CDK4 Mutant Targeted by Cytolytic T Lymphocytes in a Human Melanoma

1995 • 1,147 citations

The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.

1993 • 986 citations

A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.

1994 • 934 citations

Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection.

1994 • 921 citations

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.

1994 • 850 citations

Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes.

1994 • 771 citations

BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes

1995 • 598 citations

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.

1995 • 591 citations

Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes.

1994 • 584 citations

Genes regulating HLA class I antigen expression in T-B lymphoblast hybrids

1985 • 580 citations

Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression.

1995 • 552 citations

HLA-A2.1-Associated Peptides from a Mutant Cell Line: A Second Pathway of Antigen Presentation

1992 • 522 citations

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1992 • 502 citations

Reverse ELISPOT assay for clonal analysis of cytokine production I. Enumeration of gamma-interferon-secreting cells

1988 • 496 citations

Quantitative analysis of the human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocyte (CTL) response at different stages of HIV-1 infection: differential CTL responses to HIV-1 and Epstein-Barr virus in late disease.

1993 • 427 citations

Two tyrosinase nonapeptides recognized on HLA‐A2 melanomas by autologous cytolytic T lymphocytes

1994 • 421 citations

Presentation of viral antigen controlled by a gene in the major histocompatibility complex

1990 • 381 citations

The cognitive paradigm and the immunological homunculus

1992 • 375 citations

Quantification of antigen specific CD8+ T cells using an ELISPOT assay

1995 • 367 citations

Antigenic oscillations and shifting immunodominance in HIV-1 infections

1995 • 325 citations

The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice.

1991 • 306 citations

Induction of tumor-reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1.

1995 • 296 citations

Human CD4+ T cells specifically recognize a shared melanoma-associated antigen encoded by the tyrosinase gene.

1994 • 287 citations

Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes.

1995 • 282 citations

In vitro induction of human cytotoxic T lymphocyte responses against peptides of mutant and wild‐type p53

1993 • 267 citations

CTL induction by a tumour-associated antigen octapeptide derived from a murine lung carcinoma

1994 • 254 citations

Recognition of tyrosinase by tumor-infiltrating lymphocytes from a patient responding to immunotherapy.

1994 • 247 citations

T-cell-mediated cytotoxicity against autologous malignant melanoma: analysis with interleukin 2-dependent T-cell cultures.

1984 • 237 citations

A unique tumor antigen produced by a single amino acid substitution

1995 • 230 citations

Induction of anti-self-immunity to cure cancer

1995 • 207 citations

Identification of peptide sequences that potentially trigger HLA‐A2.1‐restricted cytotoxic T lymphocytes

1993 • 195 citations

Induction of pigmentation in mouse fibroblasts by expression of human tyrosinase cDNA.

1989 • 186 citations

CD4+ alpha beta T cell and gamma delta T cell responses to Mycobacterium tuberculosis. Similarities and differences in Ag recognition, cytotoxic effector function, and cytokine production.

1995 • 184 citations

An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein.

1991 • 172 citations

Limiting dilution analysis of human T cells: a useful clinical tool

1990 • 166 citations

A novel two colour ELISPOT assay

1988 • 166 citations

Precursor frequency analysis of human cytolytic T lymphocytes directed against autologous melanoma cells

1992 • 132 citations

Detection of intracellular expression and secretion of interferon‐γ at the single‐cell level after activation of human T cells with tetanus toxoid in vitro

1990 • 130 citations

CTL specific for the tyrosinase autoantigen can be induced from healthy donor blood to lyse melanoma cells.

1995 • 124 citations

Influenza and vaccinia viruses expressing malaria CD8+ T and B cell epitopes. Comparison of their immunogenicity and capacity to induce protective immunity.

1994 • 111 citations

Parallel regulation of IL-4 and IL-5 in human helminth infections.

1992 • 108 citations

Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells.

1989 • 101 citations

Analysis of antigens recognized on human melanoma cells by A2‐restricted cytolytic t lymphocytes (CTL)

1993 • 101 citations

Immunogenic variants obtained by mutagenesis of mouse mastocytoma P815. IV. Analysis of variant‐specific antigens by selection of antigen‐loss variants with cytolytic T cell clones

1982 • 59 citations

Cell‐mediated cytotoxicity for cultured autologous melanoma cells

1979 • 58 citations

T cell responses to human malignant tumours.

1992 • 48 citations

An intracisternal A‐particle sequence codes for an antigen recognized by syngeneic cytolytic T lymphocytes on a mouse spontaneous leukemia

1994 • 38 citations

Frequency analysis of tumor-reactive cytotoxic T lymphocytes in peripheral blood of a melanoma patient vaccinated with autologous tumor cells

1994 • 38 citations

Optimal collection of blood samples for the measurement of tumor necrosis factor ?

1990 • 37 citations

Vaccines Get a New Twist

1994 • 26 citations

Idiotypic and antiidiotypic T and B lymphocytes in myasthenia gravis.

1992 • 15 citations

Cell-mediated immune responsiveness to cardiac extracts by peripheral blood leukocytes from patients after myocardial infarction or open-heart surgery

1984 • 5 citations