Inositol Lipid Metabolism and Signal Transduction in Clonal Pituitary Cells
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Abstract
References (106)
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Thyrotropin-releasing hormone stimulates rapid loss of phosphatidylinositol and its conversion to 1,2-diacylglycerol and phosphatidic acid in rat mammotropic pituitary cells. Association with calcium mobilization and prolactin secretion.
1983 • 181 citations
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Inositol trisphosphate mediates thyrotropin-releasing hormone mobilization of nonmitochondrial calcium in rat mammotropic pituitary cells.
1984 • 168 citations
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CALCIUM INFLUX IS NOT REQUIRED FOR TRH TO ELEVATE FREE CYTOPLASMIC CALCIUM IN GH3CELLS
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Thyrotropin releasing hormone
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1978 • 117 citations
The interaction of lithium with thyrotropin-releasing hormone-stimulated lipid metabolism in GH3 pituitary tumour cells. Enhancement of stimulated 1,2-diacylglycerol formation
1984 • 116 citations
Thyrotropin-releasing hormone rapidly activates protein phosphorylation in GH3 pituitary cells by a lipid-linked, protein kinase C-mediated pathway.
1984 • 115 citations
Thyrotropin-Releasing Hormone (TRH) Selectively and Rapidly Stimulates Phosphatidylinositol Turnover in GH Pituitary Cells: A Possible Second Step of TRH Action*
1982 • 105 citations
Dual modulation of K channels by thyrotropin-releasing hormone in clonal pituitary cells.
1985 • 102 citations
Thyrotropin-releasing hormone rapidly and transiently stimulates cytosolic calcium-dependent protein phosphorylation in GH3 pituitary cells.
1982 • 102 citations
Thyrotropin-releasing hormone increases cytosolic free Ca2+ in clonal pituitary cells (GH3 cells): direct evidence for the mobilization of cellular calcium.
1984 • 101 citations
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1984 • 101 citations
12‐O‐Tetradecanoylphorbol 13‐acetate stimulates inositol lipid phosphorylation in intact human platelets
1984 • 99 citations
Direct stimulation by thyrotropin-releasing hormone (TRH) of polyphosphoinositide hydrolysis in GH3 cell membranes by a guanine nucleotide-modulated mechanism
1985 • 99 citations
Electrical behaviour in a line of anterior pituitary cells (GH cells) and the influence of the hypothalamic peptide, thyrotrophin releasing factor
1980 • 97 citations
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Sodium and calcium action potential in pituitary cells
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1985 • 89 citations
Phosphorylation of cardiac sarcoplasmic reticulum by a calcium-activated, phospholipid-dependent protein kinase
1980 • 82 citations
Somatostatin lowers the cytosolic free Ca2+ concentration in clonal rat pituitary cells (GH3 cells)
1984 • 81 citations
Synergistic stimulation of prolactin release by phorbol ester, A23187 and forskolin
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Evidence for the Role of Calcium and Diacylglycerol as Dual Second Messengers in Thyrotropin-Releasing Hormone Action: Involvement of Ca+2*
1984 • 76 citations
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1984 • 72 citations
Insulin and 17β-Estradiol Increase the Intracellular Prolactin Content of GH4C1Cells*
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Mechanisms of Ca2+ transport in plasma membrane vesicles prepared from cultured pituitary cells. I. Characterization of Na+/Ca2+ exchange activity.
1984 • 66 citations
Thyrotropin-releasing hormone stimulates GTP hydrolysis by membranes from GH4C1 rat pituitary tumor cells.
1984 • 62 citations
Evidence for tight coupling of thyrotropin-releasing hormone receptors to stimulated inositol trisphosphate formation in rat pituitary cells.
1985 • 60 citations
Hydrocortisone increases the number of receptors for thyrotropin-releasing hormone on pituitary cells in culture
1977 • 53 citations
Electrical Excitability in the Rat Clonal Pituitary Cell and Its Relation to Hormone Secretion
1979 • 50 citations
Biphasic effect of thyrotropin-releasing hormone on membrane K+ permeability in rat clonal pituitary cells
1981 • 48 citations
Polyphosphoinositide hydrolysis by phospholipase C is accelerated by thyrotropin releasing hormone (TRH) in clonal rat pituitary cells (GH3 cells)
1984 • 44 citations
Thyrotropin releasing hormone rapidly enhances [32P]orthophosphate incorporation into phosphatidic acid in cloned GH3 cells
1981 • 44 citations
Cell Culture Studies of Thyrotropin-Releasing Hormone Action
1977 • 40 citations
The calcium agonist Bay K 8644 stimulates secretion from a pituitary cell line
1984 • 40 citations
Relationship between biological responsiveness to phorbol esters and receptor levels in GH4C1 rat pituitary cells.
1981 • 40 citations
Thyrotropin releasing hormone stimulates metabolism of phosphatidyl inositol in GH3 cells
1981 • 37 citations
Direct evidence that burst but not sustained secretion of prolactin stimulated by thyrotropin-releasing hormone is dependent on elevation of cytoplasmic calcium.
1985 • 36 citations
The Effects of Maitotoxin on45Ca2+Flux and Hormone Release in GH3 Rat Pituitary Cells*
1985 • 36 citations
Protein kinase C as a bidirectional regulator of cell function
1985 • 33 citations
Calcium currents in GH3 cultured pituitary cells under whole-cell voltage-clamp: inhibition by voltage-dependent potassium currents.
1985 • 28 citations
Effect of 17β-Estradiol on thyroliberin responsiveness in GH3/B6 rat prolactin cells
1980 • 23 citations
Association of phorbol ester receptor down modulation with a cryptic receptor state.
1983 • 23 citations
Lowering of Cytosolic Free Ca2+by Carbachol, a Muscarinic Cholinergic Agonist, in Clonal Pituitary Cells (GH3Cells)*
1985 • 22 citations
Platelet-Derived Growth Factor Selectively Decreases Prolactin Production in Pituitary Cells in Culture*
1983 • 20 citations
Persistent activity modification of phosphatidate phosphohydrolase and fatty acyl‐CoA synthetase on incubation of adipocytes with the tumour promoter 12‐O‐tetradecanoylphorbol 13‐acetate
1985 • 17 citations
TRH-induced membrane hyperpolarization in rat clonal anterior pituitary cells
1985 • 16 citations
Neuroendocrine Perspectives
1989 • 15 citations
The role of inositol lipids in hormonal mobilization of cell-associated Ca2+
1985 • 13 citations
Characterization of voltage-sensitive calcium channels in a clonal pituitary cell line
1985 • 10 citations