Protein kinase C as a bidirectional regulator of cell function

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Reduction of epidermal growth factor receptor affinity by heterologous ligands: Evidence for a mechanism involving the breakdown of phosphoinositides and the activation of protein kinase C

1984 • 197 citations

Phorbol myristate acetate stimulates ATP-dependent calcium transport by the plasma membrane of neutrophils.

1984 • 193 citations

Protein kinase C regulation of the receptor-coupled calcium signal in histamine-secreting rat basophilic leukaemia cells

1985 • 186 citations

Phorbol esters inhibit agonist-induced [3H] inositol-1-phosphate accumulation in rat hippocampal slices

1984 • 180 citations

Modulation of brain polyphosphoinositide metabolism by ACTH-sensitive protein phosphorylation

1980 • 178 citations

Tumour‐promoting phorbol esters inhibit agonist‐induced phosphatidate formation and Ca²⁺ flux in human platelets

1985 • 173 citations

Serotonin secretion from human platelets may be modified by Ca2+-activated, phospholipid-dependent myosin phosphorylation.

1984 • 143 citations

Characterization of phorbol ester receptors and their down-modulation in GH4C1 rat pituitary cells.

1981 • 142 citations

The phorbol ester, TPA inhibits glucagon‐stimulated adenylate cyclase activity

1984 • 128 citations

12‐O‐Tetradecanoylphorbol 13‐acetate stimulates inositol lipid phosphorylation in intact human platelets

1984 • 99 citations

Phosphorylation of cardiac sarcoplasmic reticulum by a calcium-activated, phospholipid-dependent protein kinase

1980 • 82 citations