Thyrotropin releasing hormone

Stimulus‐secretion coupling: the concept and clues from chromaffin and other cells

1968 • 1,393 citations

Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)

1968 • 976 citations

Relationships between calcium and cyclic nucleotides in cell activation.

1977 • 849 citations

Establishment of Clonal Strains of Rat Pituitary Tumor Cells That Secrete Growth Hormone^1,2

1968 • 683 citations

Regulatory Peptides of the Hypothalamus

1977 • 395 citations

Characterization of Ovine Hypothalamic Hypophysiotropic TSH-releasing Factor

1970 • 375 citations

PRODUCTION OF BOTH PROLACTIN AND GROWTH HORMONE BY CLONAL STRAINS OF RAT PITUITARY TUMOR CELLS

1970 • 342 citations

Membrane Effects of Thyrotropin-Releasing Hormone and Estrogen Shown by Intracellular Recording from Pituitary Cells

1979 • 282 citations

Spontaneous calcium action potentials in a clonal pituitary cell line and their relationship to prolactin secretion

1975 • 257 citations

Visualization of membrane bound cations by a fluorescent technique

1971 • 224 citations

Intermediate role of adenosine 3′:5′-cyclic monophosphate and protein kinase during gonadotropin-induced steroidogenesis in testicular interstitial cells

1977 • 209 citations

Receptors for Thyrotropin-releasing Hormone in Prolactin-producing Rat Pituitary Cells in Culture

1973 • 206 citations

Structure of porcine thyrotropin-releasing hormone

1970 • 196 citations

Action potentials occur in cells of the normal anterior pituitary gland and are stimulated by the hypophysiotropic peptide thyrotropin-releasing hormone.

1977 • 161 citations

A Possible Role of Cyclic AMP in Mediating the Effects of Thyrotropin-Releasing Hormone on Prolactin Release and on Prolactin and Growth Hormone Synthesis in Pituitary Cells in Culture

1976 • 157 citations

Pituitary 45 Ca ion uptake and release of ACTH, GH, and TSH: effect of verapamil

1974 • 138 citations

Membrane potential changes caused by thyrotropin-releasing hormone in the clonal GH3 cell and their relationship to secretion of pituitary hormone.

1979 • 137 citations

Enrichment of Cell Types from the Rat Adenohypophysis by Sedimentation at Unit Gravity

1973 • 133 citations

Involvement of membrane calcium in the response of rabbit neutrophils to chemotactic factors as evidenced by the fluorescence of chlorotetracycline.

1979 • 128 citations

Role of calcium in the thyrotropin-releasing hormone-stimulated release of prolactin from pituitary cells in culture

1978 • 117 citations

Binding of Thyrotropin-Releasing Hormone to Plasma Membranes of Bovine Anterior Pituitary Gland

1972 • 117 citations

Guanine Nucleotides: Key Regulators of Hormone Receptor-Adenylate Cyclase Interaction

1981 • 115 citations

Receptor-mediated release of plasma membrane-associated calcium and stimulation of calcium uptake by thyrotropin-releasing hormone in pituitary cells in culture.

1981 • 113 citations

Presence of calcium ions as a requisite for the in vitro stimulation of TSH-release by hypothalamic TRF

1967 • 109 citations

Intracellular divalent cation release in pancreatic acinar cells during stimulus-secretion coupling. I. Use of chlorotetracycline as fluorescent probe.

1978 • 108 citations

Bihormonal regulation of the thyrotropin-releasing hormone receptor in mouse pituitary thyrotropic tumor cells in culture.

1978 • 106 citations

Enzymatic Dissociation and Short-Term Culture of Isolated Rat Anterior Pituitary Cells for Studies on the Control of Hormone Secretion

1976 • 97 citations

Electrical behaviour in a line of anterior pituitary cells (GH cells) and the influence of the hypothalamic peptide, thyrotrophin releasing factor

1980 • 97 citations

Dopamine inhibition of action potentials in a prolactin secreting cell line is modulated by oestrogen

1979 • 95 citations

Release and synthesis of prolactin by rat pituitary cell strains are regulated independently by thyrotropin-releasing hormone

1976 • 91 citations

Sodium and calcium action potential in pituitary cells

1977 • 91 citations

Interaction of thyrotropin releasing factor with membrane receptors of pituitary cells

1972 • 87 citations

Hypothalamic Stimulation of Growth Hormone and Thyrotropin Releasein Vitroand Pituitary 3′5′-Adenosine Cyclic Monophosphate¹

1970 • 84 citations

Intracellular divalent cation release in pancreatic acinar cells during stimulus-secretion coupling. II. Subcellular localization of the fluorescent probe chlorotetracycline.

1978 • 83 citations

Excess Production of Free Alpha Subunits by Mouse Pituitary Thyrotropic Tumor Cellsin Vitro*

1978 • 81 citations

Characteristics of the Pituitary Binding Sites for Thyrotropin—Releasing Factor

1973 • 81 citations

Tetracycline fluorescence as calcium-probe for nerve membrane with some model studies using erythrocyte ghosts

1972 • 79 citations

Evidence that Stimulation of Thyrotropin and Prolactin Secretion by Thyrotropin-Releasing Hormone Occur via Different Calcium-Mediated Mechanisms: Studies with Verapamil*

1982 • 75 citations

Stimulus-Secretion Coupling: Variations on the Theme of Calcium-Activated Exocytosis Involving Cellular and Extracellular Sources of Calcium

1978 • 72 citations

Role of calcium in the regulation of adenohypophysial hormone release

1978 • 71 citations

Acute Stimulated Hormone Release from Cultured GH₃Pituitary Cells*

1978 • 68 citations

Thyrotropin releasing hormone stimulation of prolactin release. Evidence for a membrane potential-independent, Ca2+-dependent mechanism of action.

1980 • 65 citations

Thyrotropin Release in Vitro: Stimulation by Cyclic 3′,5′-Adenosine Monophosphate

1969 • 65 citations

Effect of TRH and dopamine on cyclic AMP levels in enriched mammotroph and thyrotroph cells

1978 • 63 citations

On the Mechanism of Action of Luteinizing Hormone-Releasing Factor and Prolactin Release Inhibiting Factor 1

1973 • 62 citations

Calcium Antagonists and Hormone Release. II. Effects of Verapamil on Basal, Gonadotropin-Releasing Hormoneand Thyrotropin-Releasing Hormone-Induced Pituitary Hormone Release in Normal Subjects

1980 • 62 citations

Thyroid-stimulating hormone biosynthesis. Cellular processing, assembly, and release of subunits.

1981 • 61 citations

Thyrotropin-releasing Hormone Stimulation of Prolactin Release from Clonal Rat Pituitary Cells

1981 • 61 citations

The Involvement of Cyclic-3',5'-AMP in the Release of Hormones from The Anterior Pituitary in Vitro

1976 • 61 citations

Stimulation of 45Ca2+ efflux from rat pituitary by luteinizing hormone‐releasing hormone and other pituitary stimulants.

1976 • 59 citations

Effect of Trifluoperazine, D600, and Phenytoin on Depolarization- and Thyrotropin-Releasing Hormone- Induced Thyrotropin Release from Rat Pituitary Tissue*

1981 • 56 citations

Thyrotropin-Releasing Hormone Interactions with an Anterior Pituitary Membrane Receptor1

1973 • 55 citations

Studies on the role of calcium and cyclic nucleotides in the control of TSH secretion

1978 • 54 citations

Effects of thyroliberin and 4‐aminopyridine on action potentials and prolactin release and synthesis in rat pituitary cells in culture

1980 • 54 citations

Regulation of Thyrotropin Production by Mouse Pituitary Thyrotropic Tumor Cells in Vitro by Physiological Levels of Thyroid Hormones*

1978 • 52 citations

STUDIES ON THE ROLE OF CYCLIC AMP IN THE RELEASE OF ANTERIOR PITUITARY HORMONES*

1971 • 49 citations

Biphasic effect of thyrotropin-releasing hormone on membrane K+ permeability in rat clonal pituitary cells

1981 • 48 citations

Chlorotetracycline as a fluorescent Ca2+ probe in pancreatic islet cells.

1978 • 46 citations

Physical Characteristics of the Ca⁺⁺Compartments Associated within VitroACTH Release

1974 • 43 citations

Calcium‐dependent stimulation of prolactin release in rat anterior pituitaryin vitro by n⁶‐monobutyryl adenosine 3′,5′‐monophosphate

1972 • 43 citations

Fluorescent probe detects redistribution of cell calcium during stimulus–secretion coupling

1977 • 42 citations

⁴⁵Ca Uptake During theIn VitroRelease of Hormones from the Rat Adenohypophysis

1971 • 41 citations

Pituitary cyclic nucleotides and thyrotropin-releasing hormone action: the relationship of adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate to the release of thyrotropin and prolactin.

1980 • 40 citations

Thyrotropic tumor syndrome. A multiglandular disease induced by sustained deficiency of thyroid hormones.

1973 • 40 citations

Thyrotropin‐releasing hormone receptor: Its partial purification from bovine anterior pituitary gland and its close association with adenyl cyclase

1972 • 38 citations

Role of cyclic AMP in the action of hypothalamic regulatory hormones.

1975 • 37 citations

Regulation of Thyrotropin (TSH) Release and Production in Monolayer Cultures of Transplantable TSH-Producing Mouse Tumors¹

1976 • 35 citations

Effect of thyroliberin on the concentration of adenosine 3′:5′-phosphate and on the activity of adenosine 3′:5′-phosphate-dependent protein kinase in prolactin-producing cells in culture

1977 • 35 citations

TRH and prostaglandin action on RAT anterior pituitary: Dissociation between cyclic AMP levels and TSH release

1974 • 33 citations

Direct visualization of receptors for thyrotropin-releasing hormone with a fluorescein-labeled analog.

1981 • 32 citations

Stimulation of Thyrotropin (TSH) Secretion by TSH-Releasing Factor (TRF) in Organ Cultures of Anterior Pituitary

1969 • 32 citations

Enriched Populations of Rat Pituitary Thyrotrophs in Monolayer Culture*

1978 • 32 citations

Regulation of de Novo Biosynthesis of Thyrotropin in Normal, Hyperplastic, and Neoplastic Thyrotrophs*

1981 • 31 citations

Effects of Thyroid Hormones and Thyrotropin-Releasing Hormone on Thyrotropin Biosynthesis by Mouse Pituitary Tumor Cells in Vitro*

1981 • 31 citations

Adenylyl Cyclase and Cyclic Nucleotide Phosphodiesterases in GH-Strains of Rat Pituitary Cells¹

1977 • 29 citations

Calcium and Calcium-Antagonistic Effects on Prolactin and Growth Hormone Responses to Thyrotropin-Releasing Hormone and L-Dopa in Man

1981 • 29 citations

On the role of extracellular Ca2+ for prolactin release and adenosine 3′:5′-monophosphate formation induced by thyroliberin in cultured rat pituitary cells

1980 • 28 citations

Thyrotropin-Releasing Hormone (TRH) Action in Mouse Thyrotropic Tumor Cells in Culture: Evidence against a Role for Adenosine 3′,5′-Monophosphate as a Mediator of TRH-Stimulated Thyrotropin Release*

1980 • 27 citations

Alterations in Transmembrane Potential of Adenohypophysial Cells in Elevated Potassium and Calcium-Free Media

1973 • 27 citations

Evidence that TRH stimulates secretion of TSH by two calcium-mediated mechanisms

1982 • 23 citations

mRNA-directed biosynthesis of alpha and beta subunits of thyrotropin. Processing of pre-subunits to glycosylated forms.

1979 • 20 citations

CELLULAR HETEROGENEITY IN PRIMARY M0N0LAYER CULTURES OF MOUSE PITUITARY THYROTROPIC TUMORS: SEPARATION OF THYROTROPHS1

1978 • 20 citations

Role of calcium in acute stimulated release of prolactin from neoplastic GH3 cells

1981 • 19 citations

Receptor affinity and biological potency of thyroid hormones in thyrotropic cells.

1979 • 18 citations

Evidence for a Possible Role for Ca⁺⁺in the 3,5,3’-Triiodothyronine Inhibition of Thyrotropin-Releasing Hormone-Induced Secretion of Thyrotropin by Rat Anterior Pituitaryin Vitro*

1981 • 16 citations

Binding of thyrotropin releasing hormone by thyrotropin-secreting cells

1973 • 16 citations

TSH and ACTH Secretion and Cyclic Adenosine 3'5' Monophosphate Content following Stimulation with TRH or Lysine Vasopressin in Vitro: Suppression by Thyroxine and Dexamethasone

1978 • 14 citations

A study of the bioloical activity and resistance to phosphodiesterase of some derivatives and analogues of cyclic AMP.

1972 • 14 citations

Thyrotropin-releasing Hormone Stimulation of Adrenocorticotropin Production by Mouse Pituitary Tumor Cells in Culture

1980 • 12 citations

Evidence that thyrotropin-releasing hormone transiently decreases membrane potential in mouse pituitary thyrotropic tumor cells in culture as monitored by triphenylmethylphosphonium ion.

1981 • 12 citations

Interaction of calcium and cyclic nucleotides in thyroliberin-stimulated prolactin release

1981 • 10 citations

Correlation between 3′,5′, c-AMP levels and thyrotropin in separated rat pituitary thyrotropic cells

1978 • 6 citations

[Role of 3'-5'-monophosphate cyclic adenosine in the liberation of pituitary TSH].

1969 • 3 citations