Replication of plasmids in gram-negative bacteria

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

1978 • 4,472 citations

Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans

1979 • 3,210 citations

Compilation and analysis ofEscherichia colipromoter DNA sequences

1983 • 2,228 citations

Intracellular Protein Degradation in Mammalian and Bacterial Cells

1974 • 1,775 citations

Construction of Biologically Functional Bacterial Plasmids In Vitro

1973 • 1,699 citations

Determinant of cistron specificity in bacterial ribosomes

1975 • 1,363 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles

1983 • 1,256 citations

Specific-purpose plasmid cloning vectors II. Broad host range, high copy number, RSF 1010-derived vectors, and a host-vector system for gene cloning in Pseudomonas

1981 • 1,103 citations

DNA bending at adenine · thymine tracts

1986 • 1,032 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

An evolutionary perspective on synonymous codon usage in unicellular organisms

1986 • 874 citations

Histonelike proteins of bacteria

1987 • 699 citations

Duplex opening by dnaA protein at novel sequences in initiation of replication at the origin of the E. coli chromosome

1988 • 678 citations

The dnaA protein complex with the E. coli chromosomal replication origin (oriC) and other DNA sites

1984 • 673 citations

Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells.

1986 • 650 citations

PROTEIN-NUCLEIC ACID INTERACTIONS IN TRANSCRIPTION: A Molecular Analysis

1984 • 620 citations

Codon usage in regulatory genes inEscherichia colidoes not reflect selection for ‘rare’ codons

1986 • 539 citations

The Escherichia coli dnaB replication protein is a DNA helicase.

1986 • 510 citations

Formation of an RNA primer for initiation of replication of ColE1 DNA by ribonuclease H.

1980 • 496 citations

E. coli DNA binding protein HU forms nucleosome-like structure with circular double-stranded DNA

1979 • 459 citations

ATP activates dnaA protein in initiating replication of plasmids bearing the origin of the E. coli chromosome

1987 • 454 citations

Multimerization of high copy number plasmids causes instability: Cole 1 encodes a determinant essential for plasmid monomerization and stability

1984 • 443 citations

Determinants of messenger RNA stability

1987 • 414 citations

Identification and classification of bacterial plasmids

1988 • 396 citations

Translation is a non-uniform process

1984 • 387 citations

Linear Plasmids of the Bacterium Borrelia burgdorferi Have Covalently Closed Ends

1987 • 379 citations

Complete nucleotide sequence and gene organization of the broad-host-range plasmid RSF1010

1989 • 379 citations

Inhibition of ColE1 RNA primer formation by a plasmid-specified small RNA.

1981 • 362 citations

Interaction of the Escherichia coli HU protein with DNA

1986 • 321 citations

Plasmid vector pBR322 and its special-purpose derivatives — a review

1986 • 311 citations

Incompatibility Group P Plasmids: Genetics, Evolution, and Use in Genetic Manipulation

1987 • 310 citations

Multiple DNA-pRotein Interactions Governing High-Precision DNA Transactions

1986 • 302 citations

Control of cole 1 plasmid replication: The process of binding of RNA I to the primer transcript

1984 • 298 citations

Structure of the ColE1 Rop protein at 1.7 Å resolution

1987 • 297 citations

Codon usage can affect efficiency of translation of genes inEscherichia coli

1984 • 290 citations

Transcription from efficient promoters can interfere with plasmid replication and diminish expression of plasmid specified genes.

1982 • 281 citations

Unusual DNA Structures

2011 • 277 citations

Purified dnaA protein in initiation of replication at the Escherichia coli chromosomal origin of replication.

1983 • 275 citations

Plasmid ColE1 incompatibility determined by interaction of RNA I with primer transcript.

1981 • 262 citations

Circular R-Factor Molecules Controlling Penicillinase Synthesis, Replicating in Escherichia coli Under Either Relaxed or Stringent Control

1970 • 250 citations

Extensive unwinding of the plasmid template during staged enzymatic initiation of DNA replication from the origin of the Escherichia coli chromosome

1986 • 249 citations

In vitro assembly of a prepriming complex at the origin of the Escherichia coli chromosome.

1987 • 248 citations

Interactions of bacteriophage and host macromolecules in the growth of bacteriophage lambda

1984 • 246 citations

Replication control in a composite plasmid constructed by in vitro linkage of two distinct replicons

1976 • 246 citations

Molecular Nature of Two Nonconjugative Plasmids Carrying Drug Resistance Genes

1974 • 243 citations

DNA polymerase as a requirement for the maintenance of the bacterial plasmid colicinogenic factor E1

1970 • 239 citations

Codon usage inPseudomonas aeruginosa

1988 • 236 citations

Direct Evidence for DNA Bending at the Lambda Replication Origin

1987 • 233 citations

The integration host factor of Escherichia coli binds to bent DNA at the origin of replication of the plasmid pSC101

1987 • 228 citations

Hemimethylation prevents DNA replication in E. coli

1987 • 227 citations

Nucleotide sequence of small ColE1 derivatives: Structure of the regions essential for autonomous replication and colicin E1 immunity

1979 • 226 citations

Control of cole 1 plasmid replication: Enhancement of binding of RNA I to the primer transcript by the rom protein

1984 • 216 citations

Regions of broad-host-range plasmid RK2 involved in replication and stable maintenance in nine species of gram-negative bacteria

1985 • 213 citations

Origin of replication of colicin E1 plasmid DNA.

1977 • 212 citations

Gene transfer among bacteria in soil and aquatic environments: a review

1987 • 207 citations

P1 plasmid replication: Replicon structure

1984 • 207 citations

The origin of replication of plasmid p15A and comparative studies on the nucleotide sequences around the origin of related plasmids

1983 • 205 citations

Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

1981 • 204 citations

Nucleotide sequence and gene organization of ColE1 DNA.

1985 • 201 citations

Comparison of the Deoxyribonucleic Acid Molecular Weights and Homologies of Plasmids Conferring Linked Resistance to Streptomycin and Sulfonamides

1974 • 198 citations

WORKSHOP SUMMARY: Regulation of Plasmid Replication

1980 • 193 citations

Host:Vector Systems for Gene Cloning in Pseudomonas

1982 • 189 citations

Revised Interpretation of the Origin of the pSC101 Plasmid

1977 • 188 citations

Sequence specificity of the P1 modification methylase (M·Eco P1) and the DNA methylase (M·Eco dam) controlled by the Escherichia coli dam gene

1978 • 181 citations

Protein HU in the enzymatic replication of the chromosomal origin of Escherichia coli.

1984 • 180 citations

Specialized nucleoprotein structures at the origin of replication of bacteriophage lambda: localized unwinding of duplex DNA by a six-protein reaction.

1986 • 179 citations

An Escherichia coli replication protein that recognizes a unique sequence within a hairpin region in phi X174 DNA.

1980 • 177 citations

Nucleotide sequence of the region of the origin of replication of the broad host range plasmid RK2

1981 • 174 citations

Regions of broad-host-range plasmid RK2 which are essential for replication and maintenance

1980 • 173 citations

Relationship of Group P1 Plasmids Revealed by Heteroduplex Experiments: RP1, RP4, R68 and RK2 Are Identical

1979 • 172 citations

Sequence-induced DNA curvature at the bacteriophage λ origin of replication

1985 • 171 citations

Control of replication of bacterial plasmids: Genetics, molecular biology, and physiology of the plasmid R1 system

1984 • 164 citations

Helicase action of dnaB protein during replication from the Escherichia coli chromosomal origin in vitro.

1987 • 163 citations

The phi 80 and P22 attachment sites. Primary structure and interaction with Escherichia coli integration host factor.

1985 • 163 citations

Control of primer formation for ColE1 plasmid replication: Conformational change of the primer transcript

1986 • 160 citations

Natural relationship between bacteroides and flavobacteria

1985 • 154 citations

Plasmids of medical, environmental and commercial importance.

1979 • 151 citations

Replication of pBR322 DNA in vitro with purified proteins. Requirement for topoisomerase I in the maintenance of template specificity.

1985 • 151 citations

Effects of methylation on the stability of nucleic acid conformations. Studies at the polymer level.

1978 • 150 citations

Tn4351 transposes in Bacteroides spp. and mediates the integration of plasmid R751 into the Bacteroides chromosome

1986 • 147 citations

Initiation protein induced helix destabilization at the λ origin: A prepriming step in DNA replication

1988 • 147 citations

The Structure of a Transcriptional Unit on Colicin E1 Plasmid

1979 • 143 citations

Translational efficiency of the Escherichia coli adenylate cyclase gene: mutating the UUG initiation codon to GUG or AUG results in increased gene expression.

1985 • 143 citations

Local stability of DNA and RNA secondary structure and its relation to biological functions

1986 • 141 citations

Control of ColE1 plasmid replication: Binding of RNA I to RNA II and inhibition of primer formation

1986 • 141 citations

Codon usage and gene expression

1986 • 140 citations

Plasmid transfer from Escherichia coli to Bacteroides fragilis: differential expression of antibiotic resistance phenotypes.

1984 • 139 citations

Control of cole1 plasmid replication: Initial interaction of RNA I and the primer transcript is reversible

1985 • 139 citations

Complete enzymatic replication of plasmids containing the origin of the Escherichia coli chromosome.

1986 • 138 citations

Evolutionary Significance of Accessory DNA Elements in Bacteria

1981 • 137 citations

Escherichia coli integration host factor bends the DNA at the ends of IS1 and in an insertion hotspot with multiple IHF binding sites.

1987 • 137 citations

Broad host range plasmid RK2 encodes multiple kil genes potentially lethal to Escherichia coli host cells.

1982 • 134 citations

Processing enzyme ribonuclease E specifically cleaves RNA I

1985 • 134 citations

Generation time-prolonging R plasmids: Correlation between increases in the generation time of Escherichia coli caused by R plasmids and their molecular size

1980 • 132 citations

A runaway-replication mutant of plasmid R1drd-19: Temperature-dependent loss of copy number control

1978 • 132 citations

Replication of plasmid pSC101 inEscherichia coli K12: Requirement fordnaA function

1977 • 130 citations

Multiple mechanisms for initiation of ColE1 DNA replication: DNA synthesis in the presence and absence of ribonuclease H

1987 • 129 citations

Genetic and molecular characterization of the Pseudomonas plasmid pVS1

1984 • 126 citations

Complete sequence of pSC101

1984 • 125 citations

Plasmid R6K DNA replication

1982 • 124 citations

Function of RNase H in DNA replication revealed by RNase H defective mutants of Escherichia coli

1984 • 123 citations

A 37 × 103 molecular weight plasmid-encoded protein is required for replication and copy number control in the plasmid pSC101 and its temperature-sensitive derivative pHS1

1984 • 122 citations

Specialized nucleoprotein structures at the origin of replication of bacteriophage lambda: complexes with lambda O protein and with lambda O, lambda P, and Escherichia coli DnaB proteins.

1985 • 122 citations

Conservation of genes and their organization in the chromosomal replication origin region of Bacillus subtilis and Escherichia coli.

1985 • 121 citations

Replication of Colicin E1 Plasmid DNA in Cell Extracts. Origin and Direction of Replication

1974 • 120 citations

Enhancer-origin interaction in plasmid R6K involves a DNA loop mediated by initiator protein

1988 • 119 citations

Evidence that the clindamycin-erythromycin resistance gene of Bacteroides plasmid pBF4 is on a transposable element

1985 • 118 citations

Control of replication of plasmid R1: kinetics of in vitro interaction between the antisense RNA, CopA, and its target, CopT.

1988 • 118 citations

Transcription of the TOL plasmid toluate catabolic pathway operon of Pseudomonas putida is determined by a pair of co-ordinately and positively regulated overlapping promoters.

1984 • 116 citations

Conformational changes in a replication origin induced by an initiator protein

1985 • 115 citations

Host participation in plasmid maintenance: dependence upon dnaA of replicons derived from P1 and F.

1986 • 114 citations

Escherichia coli integration host factor binds specifically to the ends of the insertion sequence IS1 and to its major insertion hot-spot in pBR322

1987 • 111 citations

Mechanism of control of DNA replication and incompatibility in ColE1-type plasmids —a review

1984 • 111 citations

Nucleotide sequence of the trfA gene of broad host-range plasmid RK2

1984 • 111 citations

P1 plasmid replication: multiple functions of RepA protein at the origin.

1985 • 109 citations

Initiation of Replication of Plasmid ColE1 DNA by RNA Polymerase, Ribonuclease H, and DNA Polymerase I

1979 • 109 citations

Poly(dG)-poly(dC) sequences, under torsional stress, induce an altered DNA conformation upon neighboring DNA sequences

1985 • 108 citations

Plasmids in Bacteria

1985 • 108 citations

Effects of point mutations on formation and structure of the RNA primer for ColE1 DNA replication

1984 • 106 citations

TRANSITORY DEREPRESSION AND THE MAINTENANCE OF CONJUGATIVE PLASMIDS

1986 • 106 citations

Role of Nine Repeating Sequences of the Mini-F Genome for Expression of F-Specific Incompatibility Phenotype and Copy Number Control

1983 • 106 citations

Plasmid RP4 specifies a deoxyribonucleic acid primase involved in its conjugal transfer and maintenance

1981 • 106 citations

A linear DNA plasmid from Streptomyces rochei with an inverted terminal repetition of 614 base pairs.

1984 • 104 citations

Analysis of the trfA region of broad host-range plasmid RK2 by transposon mutagenesis and identification of polypeptide products

1984 • 103 citations

Replication of pSC101: effects of mutations in the E. coli DNA binding protein IHF

1986 • 102 citations

Suppression of cole1 replication properties by the Inc P-1 plasmid RK2 in hybrid plasmids constructed in vitro

1979 • 100 citations

Replication of the prophage P1 during the cell cycle of Escherichia coli

1977 • 100 citations

Initiation of enzymatic replication at the origin of the Escherichia coli chromosome: contributions of RNA polymerase and primase.

1985 • 99 citations

Molecular genetics of broad host range plasmid RK2

1981 • 95 citations

Positive and negative roles of an initiator protein at an origin of replication.

1986 • 93 citations

DNA methylation can enhance or induce DNA curvature.

1987 • 92 citations

Primary structure of the essential replicon of the plasmid pSC101.

1983 • 92 citations

Molecular Biology of Rna: New Perspectives

1988 • 91 citations

The nucleotide sequence of replication and maintenance functions encoded by plasmid PSCl0l

1983 • 91 citations

Complementation analysis of replication and maintenance functions of broad host range plasmids RK2 and RP1

1981 • 91 citations

Replication of the broad host range plasmid RSF1010: requirement for three plasmid-encoded proteins.

1984 • 90 citations

Replication of Colicin E1 Plasmid DNA in Minicells from a Unique Replication Initiation Site

1974 • 89 citations

Role of RNA transcripts in replication incompatibility and copy number control in antibiotic resistance plasmid derivatives

1981 • 88 citations

A review of mini-F plasmid maintenance

1985 • 86 citations

Genetic and Physical Studies on the Replication of ColE1-type Plasmids

1979 • 86 citations

Replication and incompatibility properties of segments of the origin region of replication of the broad host range plasmid RK2

1981 • 86 citations

DNA-protein interaction at the origin of DNA replication of the plasmid pSC101

1983 • 85 citations

Replication and incompatibility of F and plasmids in the IncFI group

1981 • 85 citations

Unidirectional replication of the P-group plasmid RK2

1977 • 83 citations

Replication of derivatives of the broad host range plasmid RK2 in two distantly related bacteria

1983 • 83 citations

The bacterial origin of replication, oriC

1986 • 80 citations

Effects of recombinant plasmid size on cellular processes in Escherichia coli

1987 • 79 citations

Three origins of replication are active in vivo in the R plasmid RSF1040.

1980 • 79 citations

Replication of colicin E1 plasmid DNA added to cell extracts.

1975 • 79 citations

F plasmid ccd mechanism in Escherichia coli

1986 • 78 citations

Molecular cloning and mapping of SphI restriction fragments of plasmid RP4

1983 • 78 citations

Identification of two Escherichia coli factor Y effector sites near the origins of replication of the plasmids (ColE1 and pBR322.

1980 • 78 citations

RNase H-defective mutants of Escherichia coli

1986 • 77 citations

The effects of an Escherichia coli dnaAts mutation on the replication of the plasmids colE1, pSC101, R100.1 and RTF-TC

1979 • 77 citations

Replication initiator protein of plasmid R6K autoregulates its own synthesis at the transcriptional step.

1985 • 77 citations

The importance of RNA secondary structure in CoIE1 primer formation

1982 • 76 citations

Deletion mapping of kil and kor functions in the trfA and trfB regions of broad host range plasmid RK2

1983 • 76 citations

Heteroduplex analysis of P-plasmid evolution: The role of insertion and deletion of transposable elements

1983 • 75 citations

RNA terminating within the E. coli origin of replication: Stringent regulation and control by DnaA protein

1986 • 74 citations

ThetrfBregion of broad host range plasmid RK2: the nucleotlde sequence revealsincCand key regulatory genetrfB/korA/korDas overlapping genes

1986 • 73 citations

The replication initiator protein of plasmid R6K tagged with β-galactosidase shows sequence-specific DNA-binding

1983 • 73 citations

Regulatory regions of ColE1 that are involved in determination of plasmid copy number.

1983 • 70 citations

Protein RepC is involved in copy number control of the broad host range plasmid RSF1010.

1985 • 70 citations

Nucleotide sequence analysis of RepFIC, a basic replicon present in IncFI plasmids P307 and F, and its relation to the RepA replicon of IncFII plasmids

1987 • 69 citations

Characterization of SmSu plasmids by restriction endonuclease cleavage and compatibility testing

1976 • 69 citations

Control of initiation of pMB1 replication: Purified rop protein and RNA I affect primer formation in vitro

1984 • 69 citations

The sequence encoding the 43-kilodalton trfA protein is required for efficient replication or maintenance of minimal RK2 replicons in Pseudomonas aeruginosa

1987 • 69 citations

RepA and DnaA proteins are required for initiation of R1 plasmid replication in vitro and interact with the oriR sequence.

1987 • 69 citations

ThetrfA andtrfB promoter regions of broad host range plasmid RK2 share common potential regulatory sequences

1984 • 68 citations

REGULATION OF INITIATION OF DNA REPLICATION

1979 • 68 citations

Replication control in promiscuous plasmid RK2: kil and kor functions affect expression of the essential replication gene trfA

1985 • 68 citations

The integration host factor ofEscherichia colibinds to multiple sites at plasmid R6K γ origin and is essential for replication

1988 • 68 citations

Complete nucleotide sequence of mini-Rts1 and its copy mutant

1984 • 67 citations

Properties of R1162, a broad-host-range, high-copy-number plasmid

1982 • 67 citations

The AGG codon is translated slowly inE. colieven at very low expression levels

1988 • 67 citations

Replication of colicin E1 plasmid DNA in vivo requires no plasmid-encoded proteins

1978 • 66 citations

Regulation of thetrfAandtrfBpromoters of broad host range plasmid RK2: identification of sequences essential for regulation bytrfB/korA/korD

1985 • 65 citations

Analysis of copy number control elements in the region of the vegetative replication origin of the broad host range plasmid RK2.

1984 • 65 citations

Transcription in the trfA region of broad host range plasmid RK2 is regulated by trfB and korB

1984 • 65 citations

DnaA protein binding to the plasmid origin region can substitute for primosome assembly during replication of pBR322 in vitro

1987 • 64 citations

Replication of mini RK2 plasmid in extracts of Escherichia coli requires plasmid-encoded protein TrfA and host-encoded proteins DnaA, B, G DNA gyrase and DNA polymerase III

1988 • 63 citations

The korB gene of broad host range plasmid RK2 is a major copy number control element which may act together with trfB by limiting trfA expression.

1984 • 61 citations

Autogenous regulation of synthesis of the replication protein in plasmid pSC101

1985 • 61 citations

Replication of the nonconjugative plasmid RSF1010 in Escherichia coli K-12

1978 • 60 citations

The replication initiator protein of plasmid pSC101 is a transcriptional repressor of its own cistron.

1985 • 59 citations

Structural analysis of RNA molecules involved in plasmld copy number control

1983 • 59 citations

Genetics and Breeding of Industrial Microorganisms

2020 • 58 citations

Identification of ColE1 DNA sequences that direct single strand-to-double strand conversion by a phi X174 type mechanism.

1982 • 58 citations

Map location and nucleotide sequence ofkorA, a key regulatory gene of promiscuous ptasmid RK2

1983 • 57 citations

Replication of Colicin E1 Plasmid DNA in Cell Extracts: II. Selective Synthesis of Early Replicative Intermediates

1974 • 57 citations

Control of ColE1 replication: low affinity specific binding of Rop (Rom) to RNAI and RNAII.

1988 • 56 citations

Replication of mini-P1 plasmid DNA in vitro requires two initiation proteins, encoded by the repA gene of phage P1 and the dnaA gene of Escherichia coli.

1987 • 56 citations

Transcripts within the replication origin, oric, of Excherichia coli

1987 • 55 citations

Interaction between RNA1 and the primer precursor in the regulation of ColE1 replication

1983 • 53 citations

Escherichia coli topoisomerase I can segregate replicating pBR322 daughter DNA molecules in vitro.

1986 • 52 citations

Specific cleavage of the p15A primer precursor by ribonuclease H at the origin of DNA replication.

1982 • 52 citations

Purification of ribonuclease H as a factor required for initiation ofin vitroColE1 DNA replication

1982 • 52 citations

Proteins encoded by the trans-acting replication and maintenance regions of broad host range plasmid RK2

1984 • 52 citations

The replication origin of pSC101: the nucleotide sequence and replication functions of the ori region

1984 • 51 citations

Control of pMB1 replication: inhibition of primer formation by Rop requires RNA1.

1984 • 51 citations

Two functions of the E protein are key elements in the plasmid F replication control system

1985 • 51 citations

Replication of pBR322 DNA in stringent and relaxed strains of Escherichia coli

1983 • 51 citations

Role of the π Initiation Protein and Direct Nucleotide Sequence Repeats in the Regulation of Plasmid R6K Replication

1985 • 51 citations

Requirement of the Escherichia coli dnaA gene function for ori-2-dependent mini-F plasmid replication

1987 • 50 citations

An essential replication gene, repA, of plasmid pSC101 is autoregulated

1985 • 50 citations

Nucleotide sequence of the transcriptional repressor genekorBwhich plays a key role in regulation of the copy number of broad host range plasmid RK2

1987 • 50 citations

Multiple mechanisms for expression of incompatibility by broad-host-range plasmid RK2

1982 • 49 citations

Plasmid RP4 encodes two forms of a DNA primase

1984 • 49 citations

Control of Plasmid Replication: Theoretical Considerations and Practical Solutions

1985 • 49 citations

Regulation of plasmid copy number by complementary RNAs

1985 • 48 citations

Transcriptional activation of ColE1 DNA synthesis by displacement of the nontranscribed strand

1987 • 48 citations

Complementation analysis in Pseudomonas aeruginosa of the transfer genes of the wide host range R plasmid R18

1981 • 48 citations

TheoriCunwinding bydammethylation inEscherichia coli

1988 • 48 citations

Nucleotide sequence of a DNA segment promoting transcription in Pseudomonas putida

1986 • 47 citations

Nucleotide sequence of korB, a replication control gene of broad host-range plasmid RK2

1987 • 47 citations

Cloning of the Escherichia coli gene for primosomal protein i: the relationship to dnaT, essential for chromosomal DNA replication.

1986 • 46 citations

Alternative conformations of the ColE1 replication primer modulate its interaction with RNA I

1985 • 46 citations

Factor-independent termination of transcription in a stretch of deoxyadenosine residues in the template DNA

1987 • 46 citations

DnaA protein is required for replication of the minimal replicon of the broad-host-range plasmid RK2 in Escherichia coli

1987 • 46 citations

Regulation of dnaB function in DNA replication in Escherichia coli by dnaC and lambda P gene products.

1987 • 46 citations

Purification and properties of the mini-F plasmid-encoded E protein needed for autonomous replication control of the plasmid.

1986 • 46 citations

Broad-host-range IncP-4 plasmid R1162: effects of deletions and insertions on plasmid maintenance and host range

1982 • 46 citations

Genetic organization of plasmid R1162 DNA involved in conjugative mobilization

1986 • 45 citations

korA function of promiscuous plasmid RK2: an autorepressor that inhibits expression of host-lethal gene kilA and replication gene trfA.

1985 • 45 citations

Gene control in broad host range plasmid RK2: expression, polypeptide product, and multiple regulatory functions of korB.

1986 • 45 citations

Isolation of the origin of replication of the IncW-group plasmid pSa

1982 • 44 citations

Maintenance of bacterial plasmids: Comparison of theoretical calculations and experiments with plasmid R1 in Escherichia coli

1984 • 44 citations

Copy-number of broad host-range plasmid R1162 is regulated by a small RNA

1986 • 43 citations

The complete nucleotide sequence of the colicinogenic plasmid ColA. High extent of homology with ColE1

1988 • 43 citations

Plasmid pSC101 replication mutants generated by insertion of the transposon Tn1000

1983 • 43 citations

The involvement of host replication proteins and of specific origin sequences in thein vitroreplication of miniplasmid Rl DNA

1986 • 43 citations

Isolation and characterization of megaplasmid DNA from lithoautotrophic bacteria

1984 • 42 citations

Essential genes of plasmid RK2 in Escherichia coli: trfB region controls a kil gene near trfA

1983 • 41 citations

Replication of the colicin E1 plasmid in extracts of Escherichia coli: Uncoupling of leading strand from lagging strand synthesis

1979 • 41 citations

2 Identification and Analysis of Plasmids at the Genetic Level

1984 • 41 citations

An Escherichia coli mutant thermosensitive in the B subunit of DNA gyrase: Effect on the structure and replication of the colicin E1 plasmid in vitro

1981 • 41 citations

Host control of plasmid replication: requirement for the sigma factor sigma 32 in transcription of mini-F replication initiator gene.

1987 • 40 citations

Absence of RNase H allows replication of pBR322 in Escherichia coli mutants lacking DNA polymerase I.

1984 • 40 citations

Comparison of the organisation of the genomes of phenotypically diverse plasmids of incompatibility group P: members of the IncPβ sub-group are closely related

1987 • 40 citations

Homology in the transfer origins of broad host range IncP plasmids: Definition of two subgroups of P plasmids

1983 • 40 citations

DNA replication regulated by the priming promoter

1984 • 40 citations

Characterization of the ColE1 primer-RNA1 complex: analysis of a domain of ColE1 RNA1 necessary for its interaction with primer RNA.

1985 • 39 citations

Activities of the RNAI and RNAII promoters of plasmid pBR322

1987 • 39 citations

Conditional high copy number ColE1 mutants: resistance to RNA1 inhibition in vivo and in vitro.

1988 • 38 citations

Replication of the broad host range plasmid RSF1010 in cell-free extracts ofEscherichia coliandPseudomonas aeruginosa

1982 • 38 citations

DNA synthesis is initiated at two positions within the origin of replication of plasmid R1162

1987 • 38 citations

The complete nucleotide sequence of the bacteriocinogenic plasmid CloDF13

1986 • 38 citations

Mathematical model for the control of ColE1 type plasmid replication

1986 • 38 citations

P1 plasmid replication: measurement of initiator protein concentration in vivo

1987 • 38 citations

Role and specificity of plasmid RP4-encoded DNA primase in bacterial conjugation

1986 • 38 citations

Control of the kilA gene of the broad-host-range plasmid RK2: involvement of korA, korB, and a new gene, korE

1987 • 38 citations

Insertion mutations in the promiscuous IncP-1 plasmid R18 which affect its host range between Pseudomonas species

1984 • 37 citations

P1 plasmid replication requires methylated DNA.

1987 • 37 citations

Maintenance of broad host range plasmid RK2 replicons in Pseudomonas aeruginosa

1982 • 37 citations

Comparison of dnaA nucleotide sequences of Escherichia coli, Salmonella typhimurium, and Serratia marcescens

1987 • 36 citations

Mechanism of autonomous control of theEscherichia coliF plasmid: different complexes of the initiator/repressor protein are bound to its operator and to an F plasmid replication origin

1986 • 36 citations

Two single-strand DNA initiation signals located in the oriV region of plasmid RSF1010

1988 • 36 citations

Control of replication of the broad host range plasmid RSF1010: The incompatibility determinant consists of directly repeated DNA sequences

1986 • 35 citations

Control of replication of plasmid R1: translation of the 7k reading frame in the RepA mRNA leader region counteracts the interaction between CopA RNA and CopT RNA.

1987 • 35 citations

Initiation of lagging-strand synthesis for pBR322 plasmid DNA replication in vitro is dependent on primosomal protein i encoded by dnaT.

1988 • 34 citations

Initiation of DNA replication in a ColE1-type plasmid: isolation of mutations in the ori region.

1980 • 34 citations

Recent studies on the control of plasmid replication

1988 • 34 citations

The 20 bp, directly repeated DNA sequence of broad host range plasmid R1162 exerts incompatibility in vivo and inhibits R1162 DNA replication in vitro

1987 • 34 citations

Identification of pKM101-encoded loci specifying potentially lethal gene products

1985 • 34 citations

What does the homology between E. coli tRNAs and RNAs controlling ColE1 plasmid replication mean?

1988 • 33 citations

Discriminatory function of ribonuclease H in the selective initiation of plasmid DNA replication

1982 • 33 citations

Escherichia coli mutants suppressing replication-defective mutations of the ColE1 plasmid.

1984 • 33 citations

Regulation of transcription of the repA1 gene in the replication control region of IncFII plasmid NR1 by gene dosage of the repA2 transcription repressor protein

1985 • 33 citations

Replication Determinants of the Broad Host-Range Plasmid RSF1010

1985 • 32 citations

Comparison of 10 IncP plasmids: homology in the regions involved in plasmid replication

1985 • 32 citations

Tn7 insertion mutations affecting the host range of the promiscuous IncP-1 plasmid R18

1982 • 32 citations

Molecular Genetic Analysis of the trfB and korB Region of Broad Host Range Plasmid RK2

1984 • 31 citations

Transfer of plasmids from Escherichia coli to Pseudomonas aeruginosa: characterization of a Pseudomonas aeruginosa mutant with enhanced recipient ability for enterobacterial plasmids

1983 • 31 citations

Comparison of the nucleotide sequences of the vegetative replication origins of broad host range IncP plasmids R751 and RK2 reveals conserved features of probable functional importance

1985 • 31 citations

Characterization of the DNA binding domain of bacteriophage lambda O protein.

1986 • 31 citations

Genetic analysis of the parB + locus of plasmid R1

1987 • 31 citations

Gene regulation in plasmid RK2: positive control by korA in the expression of korC

1984 • 30 citations

Escherichia coli relA strains as hosts for amplification of pBR322 plasmid DNA

1985 • 30 citations

A replication initiator protein enhances the rate of hybrid formation between a silencer RNA and an activator RNA

1987 • 29 citations

A Comparison of Six DNA Bending Models

1987 • 29 citations

Copy number of the broad host-range plasmid R1162 is determined by the amounts of essential plasmid-encoded proteins

1985 • 28 citations

Analysis of transcription from the trfA promoter of broad host range plasmid RK2 in Escherichia coli, Pseudomonas putida, and Pseudomonas aeruginosa

1987 • 28 citations

Influence of N⁶‐methylation of residue A(5) on the conformational behaviour of d(C‐C‐G‐A‐A‐T‐T‐C‐G‐G) in solution studied by ¹H‐NMR spectroscopy

1987 • 27 citations

Inhibition of F plasmid replication in htpR mutants of Escherichia coli deficient in sigma 32 protein

1986 • 26 citations

Directly repeated, 20-bp sequence of plasmid R1162 DNA is required for replication, expression of incompatibility, and copy-number control

1986 • 26 citations

Transcriptional pausing in a region important for plasmid NR1 replication control

1987 • 26 citations

Involvement of kil and kor genes in the phenotype of a host-range mutant of RP4

1984 • 25 citations

Dna and protein interactions in the regulation of plasmid replication

1987 • 25 citations

Conservation of a common ‘backbone’ in the genetic organization of the incP plasmids RP4 and R751

1987 • 25 citations

Plasmid pSC101 replication in integratively suppressed cells requires dnaA function

1979 • 25 citations

Analysis of the vegetative replication origin of broad-host-range plasmid RK2 by transposon mutagenesis

1986 • 25 citations

Conditional lethal mutants of the kilB determinant of broad host range plasmid RK2

1983 • 25 citations

Restriction endonuclease analyses of the incompatibility group P-1 plasmids RK2, RP1, RP4, R68, and R68.45

1981 • 25 citations

Nucleotide sequences required for a ColE1-type plasmid to replicate in Escherichia coli cells with or without RNase H

1987 • 24 citations

Tn501 insertion mutagenesis in Pseudomonas aeruginosa PAO

1984 • 24 citations

Broad Host-Range Plasmid R1162: Replication, Incompatibility, and Copy-Number Control

1985 • 24 citations

Functionality of the dnaA protein binding site in DNA replication is orientation-dependent.

1988 • 23 citations

Effect of dna mutations on the replication of plasmid pSC101 in Escherichia coli K-12

1979 • 22 citations

Analysis of dominant copy number mutants of the plasmid pMB1

1985 • 22 citations

Incompatibility repressor in a RepA-like replicon of the IncFI plasmid ColV2-K94

1986 • 22 citations

Control of replication of FII plasmids: Comparison of the basic replicons and of the copB systems of plasmids R100 and R1

1985 • 22 citations

P1 Plasmid Maintenance: A Paradigm of Precise Control

1985 • 22 citations

Evidence for the involvement of the incC locus of broad host range plasmid RK2 in plasmid maintenance

1986 • 22 citations

Start sites for bidirectional in vitro DNA replication inside the replication origin, oriC, of Escherichia coli.

1987 • 22 citations

RNase H and replication of ColE1 DNA in Escherichia coli

1986 • 21 citations

Aspects of plasmid F maintenance in Escherichia coli

1988 • 20 citations

Transfer and maintenance of small, mobilizable plasmids with ColE1 replication origins in Legionella pneumophila

1988 • 20 citations

Nucleotide sequence and functional properties of DNA encoding incompatibility in the broad host-range plasmid R1162

1984 • 20 citations

RNA1 is sufficient to mediate plasmid ColE1 incompatibility in vivo

1984 • 19 citations

Effects of GUG and AUG initiation codons on the expression of lacZ in Escherichia coli

1986 • 19 citations

A rapid electrophoretic method for the measurement of plasmid copy number

1986 • 19 citations

DNA Replication, 1982 Supplement

1983 • 18 citations

Replication of the ampicillin resistance plasmid RSF1030 in extracts of Escherichia coli: Separation of the replication cycle into early and late stages

1977 • 18 citations

Mini-F E protein: the carboxy-terminal end is essential for E gene repression and mini-F copy number control

1986 • 18 citations

Initiation of DNA replication in Escherichia coli

1987 • 16 citations

The replication origin of pSC101: Replication properties of a segment capable of autonomous replication.

1984 • 16 citations

Instability of a high-copy-number mutant of a miniplasmid derived from broad host range IncP plasmid RK2

1983 • 16 citations

The nucleotide sequences of the replication origins of plasmids ColA and ColD

1985 • 16 citations

Suppressors of a temperature-sensitive copy-number mutation in plasmid NTP1

1983 • 16 citations

Suppression of ColE1 RNA-RNA mismatch mutations in vivo by the ColE1 rop protein

1987 • 15 citations

Overinitiation of chromosome and plasmid replication in a dnaAcos mutant of Escherichia coli K12

1984 • 15 citations

Mode of insertion of the broad-host-range plasmid RP4 and its derivatives into the chromosome of Myxococcus xanthus

1987 • 15 citations

A comparison of the origin of replication of pSa with R6K

1983 • 15 citations

Replication of plasmid RK2 in vitro by a DNA-membrane complex: evidence for initiation of replication and its coupling to transcription and translation

1986 • 15 citations

Replication of a low-copy-number plasmid by a plasmid DNA-membrane complex extracted from minicells of Escherichia coli

1982 • 15 citations

RNA polymerase pauses in vitro within the Escherichia coli origin of replication at the same sites where termination occurs in vivo.

1987 • 15 citations

Integrative suppression of dnaA(Ts) mutations mediated by plasmid F in Escherichia coli is a DnaA-dependent process

1987 • 14 citations

Construction and characterization of pBR322-derived plasmids with deletions of the RNA I region

1986 • 14 citations

Occurrence of deletion plasmids at high rates after conjugative transfer of the plasmids RP4 and RK2 from Escherichia coli to Alcaligenes eutrophus H16

1983 • 14 citations

Isolation and characterization of mutants affecting functional domains of ColE1 RNAI

1985 • 14 citations

cis-acting mutations that affect rop protein control of plasmid copy number.

1984 • 14 citations

Transposition from RP4 to other replicons of a tellurite-resistance determinant not normally expressed by IncPα plasmids

1987 • 14 citations

Identification and characterization of mutations responsible for a runaway replication phenotype of plasmid R1

1987 • 13 citations

Replication of Bacteriophage DNA

1983 • 12 citations

Rifampicin-resistant initiation of DNA synthesis on the isolated strands of CoIE plasmid DNA

1981 • 12 citations

Replication control of IncP plasmids

1984 • 12 citations

Two domains at the origin are required for replication and maintenance of broad-host-range plasmid R1162

1987 • 12 citations

A new IncQ plasmid R89S: Properties and genetic organization

1987 • 12 citations

Characterization and Incompatibility Properties of ROM- Derivatives of pBR322-based Plasmids

1986 • 12 citations

Evolution of bacterial surface exclusion against incompatible plasmids

1985 • 11 citations

Preliminary evidence for the linear nature ofThiobacillus versutuspTAV2 plasmid

1988 • 11 citations

Stability of IncQ and IncP-1 vector plasmids inRhizobiumspp.

1987 • 10 citations

Role of IncP-1 plasmid primase in conjugation betweenPseudomonasspecies

1988 • 10 citations

Genetic basis of a Tn7 insertion mutation in the trfA region of the promiscuous IncP-1 plasmid R18 which affects its host range

1987 • 10 citations

Construction of a shuttle vector betweenEscherichia coli andZymomonas anaerobia

1987 • 10 citations

Effect of a broad‐host range plasmid on growth dynamics of Escherichia coli and Pseudomonas putida

1987 • 10 citations

Genetic analysis of bacterial plasmid promiscuity

1986 • 10 citations

Methylation-dependent transcription controls plasmid replication of the CloDF13 cop-1(Ts) mutant

1986 • 9 citations

Phenotypic expression of mutations in a wide-host-range R plasmid in Escherichia coli and Rhizobium meliloti

1982 • 9 citations

Characterization of the drug resistance plasmid NTP16

1987 • 9 citations

DNA sequence analysis of host range mutants of the promiscuous IncP-1 plasmids R18 and R68 with Tn7 insertions in oriV

1987 • 8 citations

Detection of displacement (“D”) loops with the properties of a replicating intermediate synthesized by a DNA/membrane complex derived from the low-copy-number plasmid RK2

1984 • 8 citations

Replication and maintenance of promiscuous plasmids of gram-negative bacteria.

1987 • 8 citations

Narrow-host-range IncP Plasmid pHH502-1 Lacks a Complete IncP Replication System

1987 • 8 citations

Coexistence of incompatible plasmids in a bacterial population living under a feast and famine regime

1986 • 7 citations

Physiological studies on pBR 322 DNA amplification in an Escherichia coli relA strain

1986 • 7 citations

Nucleotide Sequence of the Replication Region of Plasmid R401 and Its Incompatibility Function

1985 • 7 citations

Changes in RNA Secondary Structure May Mediate the Regulation of IncFII Plasmid Gene Expression and DNA Replication

1987 • 7 citations

Properties of plasmids from Methylomonas clara

1984 • 6 citations

AdnaB-like protein ofPseudomonas aeruginosa

1987 • 6 citations

Characterization of a promoter up mutation in the -35 region of the promoter of the primer for ColE1 replication

1987 • 6 citations

Maintenance of plasmid pSC101 in Escherichia coli requires the host primase

1985 • 6 citations

Regions of homology in small colicinogenic plasmids

1984 • 6 citations

Accumulation of ColE1 early replicative intermediates catalyzed by extracts of Escherichia coli dnaG mutant strains

1983 • 5 citations

The nucleotide sequence of cea* and the region of origin of plasmid pKY-1.

1986 • 5 citations

Plasmid partitioning in Escherichia coli.

1985 • 3 citations

A conditional high-copy-number plasmid derivative of pBR322.

1988 • 2 citations