DNA synthesis is initiated at two positions within the origin of replication of plasmid R1162

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA

1972 • 2,842 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Construction of Biologically Functional Bacterial Plasmids In Vitro

1973 • 1,699 citations

Plasmid ColE1 as a Molecular Vehicle for Cloning and Amplification of DNA

1974 • 541 citations

A procedure for the large-scale isolation of highly purified plasmid DNA using alkaline extraction and binding to glass powder

1982 • 259 citations

Comparison of the Deoxyribonucleic Acid Molecular Weights and Homologies of Plasmids Conferring Linked Resistance to Streptomycin and Sulfonamides

1974 • 198 citations

Interaction of the plasmid R6K-encoded replication initiator protein with its binding sites on DNA

1983 • 136 citations

Purified bacteriophage λ O protein binds to four repeating sequences at the λ replication origin

1981 • 119 citations

Replication of the broad host range plasmid RSF1010: requirement for three plasmid-encoded proteins.

1984 • 90 citations

Plasmid P1 replication: negative control by repeated DNA sequences.

1984 • 70 citations

Protein RepC is involved in copy number control of the broad host range plasmid RSF1010.

1985 • 70 citations

Replication of the nonconjugative plasmid RSF1010 in Escherichia coli K-12

1978 • 60 citations

Isolation and characterization of transducing coliphage fd carrying a kanamycin resistance gene

1978 • 51 citations

Copy-number of broad host-range plasmid R1162 is regulated by a small RNA

1986 • 43 citations

Replication of the broad host range plasmid RSF1010 in cell-free extracts ofEscherichia coliandPseudomonas aeruginosa

1982 • 38 citations

Mechanism of autonomous control of theEscherichia coliF plasmid: different complexes of the initiator/repressor protein are bound to its operator and to an F plasmid replication origin

1986 • 36 citations

Directly repeated, 20-bp sequence of plasmid R1162 DNA is required for replication, expression of incompatibility, and copy-number control

1986 • 26 citations