Escherichia coli integration host factor bends the DNA at the ends of IS1 and in an insertion hotspot with multiple IHF binding sites.

A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system

1981 • 1,991 citations

Rapid and efficient cosmid cloning

1981 • 1,897 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

In vitro insertional mutagenesis with a selectable DNA fragment

1984 • 1,708 citations

The locus of sequence-directed and protein-induced DNA bending

1984 • 1,453 citations

DNA Insertion Elements, Plasmids and Episomes

1978 • 1,294 citations

DNA bending at adenine · thymine tracts

1986 • 1,032 citations

Diffusion-Controlled Macromolecular Interactions

1985 • 699 citations

Bent helical structure in kinetoplast DNA

1982 • 595 citations

Diffusion-driven mechanisms of protein translocation on nucleic acids. 3. The Escherichia coli lac repressor-operator interaction: kinetic measurements and conclusions

1981 • 579 citations

Calculation of binding isotherms for heterogeneous polymers

1968 • 432 citations

E. coli integration host factor binds to specific sites in DNA

1984 • 419 citations

The DNA binding domain and bending angle of E. coli CAP protein

1986 • 322 citations

The molecular basis of DNA–protein recognition inferred from the structure of cro repressor

1982 • 303 citations

Kinked DNA in crystalline complex with EcoRI endonuclease

1984 • 303 citations

Multiple DNA-pRotein Interactions Governing High-Precision DNA Transactions

1986 • 302 citations

Revised sequence of the tetracycline-resistance gene of pBR322

1983 • 287 citations

Purification and properties of the Escherichia coli protein factor required for lambda integrative recombination.

1981 • 261 citations

On the sequence determinants and flexibility of the kinetoplast DNA fragment with abnormal gel electrophoretic mobilities

1985 • 240 citations

Conformational change in the DNA associated with an unusual promoter mutation in a tRNA operon of Salmonella

1984 • 225 citations

Control of phage λ development by stability and synthesis of cll protein: Role of the viral clll and host hflA, himA and himD genes

1982 • 210 citations

Equilibrium studies of the cyclic AMP receptor protein-DNA interaction

1984 • 178 citations

DNA loops induced by cooperative binding of λ repressor

1986 • 165 citations

The phi 80 and P22 attachment sites. Primary structure and interaction with Escherichia coli integration host factor.

1985 • 163 citations

Primary structure of the hip gene of Escherichia coli and of its product, the β subunit of integration host factor

1985 • 159 citations

Linker Tailing: Unphosphorylated Linker Oligonucleotides for Joining DNA Termini

1984 • 154 citations

CAP and RNA polymerase interactions with thelacpromoter: binding stoichiometry and long range effects

1983 • 150 citations

The interaction of recombination proteins with supercoiled DNA: Defining the role of supercoiling in lambda integrative recombination

1986 • 148 citations

Anomalous electrophoresis of deoxyribonucleic acid restriction fragments on polyacrylamide gels

1983 • 142 citations

A phage repressor–operator complex at 7 Å resolution

1985 • 140 citations

Control of Directionality in Lambda Site Specific Recombination

1985 • 134 citations

The bacteriophage lambda int gene product. A filter assay for genetic recombination, purification of int, and specific binding to DNA.

1978 • 119 citations

Site-specific DNA condensation and pairing mediated by the int protein of bacteriophage lambda.

1982 • 119 citations

Conformational changes in a replication origin induced by an initiator protein

1985 • 115 citations

Escherichia coli integration host factor binds specifically to the ends of the insertion sequence IS1 and to its major insertion hot-spot in pBR322

1987 • 111 citations

Replication of pSC101: effects of mutations in the E. coli DNA binding protein IHF

1986 • 102 citations

Knotting of DNA caused by a genetic rearrangement

1983 • 100 citations

Role of Escherichia coli IHF protein in lambda site-specific recombination

1986 • 99 citations

Synergistic effect of himA and gyrB mutations: evidence that him functions control expression of ilv and xyl genes

1984 • 87 citations

Binding and bending of the lambda replication origin by the phage O protein.

1985 • 87 citations

Primary Structure of the himA Gene of Escherichia coli: Homology with DNA-binding Protein HU and Association with the Phenylalanyl-tRNA Synthetase Operon

1984 • 83 citations

Analysis of gamma delta resolvase mutants in vitro: evidence for an interaction between serine-10 of resolvase and site I of res.

1986 • 61 citations

Specificity of insertion of IS1

1985 • 60 citations

The sequence of a region of bacteriophage φX174 DNA coding for parts of genes A and B

1977 • 58 citations

Biochemical analysis of att-defective mutants of the phage lambda site-specific recombination system

1982 • 58 citations

Regulation of Mu transposition II. The Escherichia coli HimD protein positively controls two repressor promoters and the early promoter of bacteriophage Mu

1984 • 58 citations

Translation initiation of bacteriophage lambda gene cII requires integration host factor

1986 • 53 citations

Mutations in an integration host factor-binding site: effect on lambda site-specific recombination and regulatory implications

1986 • 48 citations

Expression of F transfer functions depends on the Escherichia coli integration host factor

1987 • 41 citations

Visualization of cAMP receptor protein-induced DNA kinking by electron microscopy

1984 • 27 citations

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