Effects of recombinant plasmid size on cellular processes in Escherichia coli

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Experiments in molecular genetics

1972 • 28,260 citations

Methods in Enzymology , Vol

1966 • 26,261 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Nature of Col E ₁ Plasmid Replication in Escherichia coli in the Presence of Chloramphenicol

1972 • 1,202 citations

Trans-complementable copy-number mutants of plasmid ColE1

1980 • 975 citations

Multimerization of high copy number plasmids causes instability: Cole 1 encodes a determinant essential for plasmid monomerization and stability

1984 • 443 citations

Determination of plasmid copy number by fluorescence densitometry

1983 • 291 citations

Transcription from efficient promoters can interfere with plasmid replication and diminish expression of plasmid specified genes.

1982 • 281 citations

A PERSPECTIVE ON THE APPLICATION OF GENETIC ENGINEERING: STABILITY OF RECOMBINANT PLASMID

1981 • 267 citations

Control of cole 1 plasmid replication: Enhancement of binding of RNA I to the primer transcript by the rom protein

1984 • 216 citations

Characterization of a mini-ColC1 plasmid

1976 • 196 citations

WORKSHOP SUMMARY: Regulation of Plasmid Replication

1980 • 193 citations

Control of ColE1 DNA replication: the rop gene product negatively affects transcription from the replication primer promoter.

1982 • 189 citations

Regulation of plasmid replication

1984 • 134 citations

Generation time-prolonging R plasmids: Correlation between increases in the generation time of Escherichia coli caused by R plasmids and their molecular size

1980 • 132 citations

Segregational instability of pUB110-derived recombinant plasmids in Bacillus subtilis

1985 • 127 citations

Effects of promoter strengths and growth conditions on copy number of transcription-fusion vectors.

1984 • 127 citations

Maintenance of some ColE1-type plasmids in chemostat culture

1980 • 126 citations

Analysis of growth rate effects on productivity of recombinant Escherichia coli populations using molecular mechanism models

1984 • 116 citations

Replication of R-factor R1 in Scherichia coli K-12 at different growth rates

1975 • 108 citations

Persistence of the pBR 322 plasmid in Escherichia coli K 12 grown in chemostat cultures

1980 • 80 citations

On the Nature of the Changes Induced in Escherichia coli by Osmotic Shock

1967 • 79 citations

An operational strategy for unstable recombinant DNA cultures

1984 • 58 citations

Modeling, optimization and control of semi-batch bioreactors

2005 • 54 citations

Batch fermentation kinetics with (unstable) recombinant cultures

1982 • 45 citations

Isolation and characterization of ColE1-derived plasmid copy-number mutant.

1978 • 41 citations

Isolation and characterization of cloned DNA sequences containing ribosomal protein genes of Drosophila melanogaster.

1984 • 38 citations

Ampicillin effects on five recombinant Escherichia coli strains: Implications for selection pressure design

1985 • 31 citations

Colicin synthesis and cell death

1985 • 23 citations

ColD-derived cloning vectors that autoamplify in the stationary phase of bacterial growth

1985 • 18 citations