Nicotinic Receptor-Induced Apoptotic Cell Death of Hippocampal Progenitor Cells

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

A model for p53-induced apoptosis

1997 • 2,502 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

1997 • 1,142 citations

The Diversity of Neuronal Nicotinic Acetylcholine Receptors

1993 • 1,040 citations

Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain.

1995 • 1,014 citations

Hippocampal synaptic transmission enhanced by low concentrations of nicotine

1996 • 955 citations

Isolation, Characterization, and use of Stem Cells from the CNS

1995 • 819 citations

Nicotinic Receptors in the Development and Modulation of CNS Synapses

1996 • 771 citations

Stimulation of Neuronal Acetylcholine Receptors Induces Rapid Gene Transcription

1986 • 761 citations

Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity

1996 • 701 citations

Differentiation of adult hippocampus-derived progenitors into olfactory neurons in vivo

1996 • 626 citations

The maternal and fetal physiologic effects of nicotine

1996 • 560 citations

Evidence for calcium-reducing and excitoprotective roles for the calcium-binding protein calbindin-1328k in cultured hippocampal neurons

1991 • 518 citations

Apoptosis and the cell cycle

1995 • 431 citations

Acetylcholine Activates an α-Bungarotoxin-Sensitive Nicotinic Current in Rat Hippocampal Interneurons, But Not Pyramidal Cells

1998 • 380 citations

Developmental Regulation of Nicotinic Acetylcholine Receptors

1987 • 354 citations

alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability

1995 • 264 citations

Nicotinic receptors that bind α-bungarotoxin on neurons raise intracellular free ca2+

1992 • 263 citations

Evidence for p53-Mediated Modulation of Neuronal Viability

1996 • 247 citations

The Cyclin-Dependent Kinase Inhibitor p21^WAF1 Is Required for Survival of Differentiating Neuroblastoma Cells

1996 • 226 citations

Methyllycaconitine: a selective probe for neuronal α‐bungarotoxin binding sites

1990 • 220 citations

Alpha-bungarotoxin binding to hippocampal interneurons: immunocytochemical characterization and effects on growth factor expression

1993 • 205 citations

A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans

1995 • 203 citations

Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain.

1989 • 200 citations

Intellectual Impairment in Children of Women Who Smoke Cigarettes During Pregnancy

1994 • 194 citations

Prenatal Exposure to Tobacco: II Effects on Cognitive Functioning at Age Three

1990 • 180 citations

p53 Expression Induces Apoptosis in Hippocampal Pyramidal Neuron Cultures

1997 • 169 citations

Differentiation of the immortalized adult neuronal progenitor cell line HC2S2 into neurons by regulatable suppression of the v-myc oncogene.

1996 • 163 citations

Comparison of quantitative calcium flux through NMDA, ATP, and ACh receptor channels

1995 • 156 citations

Interactions between neurons and their targets during in vivo synaptogenesis.

1978 • 152 citations

Immortal rat hippocampal cell lines exhibit neuronal and glial lineages and neurotrophin gene expression.

1992 • 151 citations

Immortalization of Neural Cells Via Retrovirus-Mediated Oncogene Transduction

1989 • 151 citations

Intellectual Impairment in Children of Women Who Smoke Cigarettes During Pregnancy

1994 • 149 citations

Neuronal progenitors as tools for cell replacement in the nervous system

1996 • 138 citations

Diversity of nicotinic acetylcholine receptors in rat brain. V. alpha-Bungarotoxin-sensitive nicotinic receptors in olfactory bulb neurons and presynaptic modulation of glutamate release.

1996 • 133 citations

Coexpression of multiple acetylcholine receptor genes in neurons: quantification of transcripts during development.

1993 • 124 citations

Regulation of α₇Nicotinic Acetylcholine Receptors in the Developing Rat Somatosensory Cortex by Thalamocortical Afferents

1996 • 123 citations

Nicotine protects cultured striatal neurones against N-methyl-D-aspartate receptor-mediated neurotoxicity

1994 • 112 citations

α-Bungarotoxin binding sites in rat hippocampal and cortical cultures: initial characterisation, colocalisation with α7 subunits and up-regulation by chronic nicotine treatment

1995 • 103 citations

Genetic and environmental aspects of the role of nicotinic receptors in neurodegenerative disorders: Emphasis on Alzheimer's disease and Parkinson's disease

1995 • 101 citations

Activation of α₇ nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons

1997 • 101 citations

Calbindin-D28k immunoreactivity and selective vulnerability to ischemia in the dentate gyrus of the developing rat

1993 • 97 citations

p53 expression overcomes p21WAF1/CIP1-mediated G1 arrest and induces apoptosis in human cancer cells

1997 • 97 citations

Arachidonic acid as a possible negative feedback inhibitor of nicotinic acetylcholine receptors on neurons

1995 • 97 citations

α-Bungarotoxin blocks the nicotinic receptor mediated increase in cell number in a neuroendocrine cell line

1994 • 92 citations

Serotonin release and cell proliferation are under the control of α‐bungarotoxin‐sensitive nicotinic receptors in small‐cell lung carcinoma cell lines

1994 • 86 citations

Expression of neuronal acetylcholine receptor genes in vertebrate skeletal muscle during development

1995 • 84 citations

SEQUENCES OF INTEREST: Rat Brain Calbindin D28: Six Domain Structure and Extensive Amino Acid Homology with Chicken Calbindin D28

1988 • 81 citations

Chapter 7: Nicotinic receptors in mammalian brain: localization and relation to cholinergic innervation

1993 • 80 citations

The nicotinic blocking agents d-tubocurare and alpha-bungarotoxin save motoneurons from naturally occurring death in the absence of neuromuscular blockade

1995 • 78 citations

Multiple Ca²⁺ signaling pathways converge on CaM kinase in PC12 cells

1992 • 71 citations

Nicotine rescues PC12 cells from death induced by nerve growth factor deprivation

1996 • 71 citations

Localization of α7 nicotinic receptor subunit mRNA and α‐bungarotoxin binding sites in developing mouse somatosensory thalamocortical system

1995 • 62 citations

Induction of Tumor Suppressor p53 and DNA Fragmentation in Organotypic Hippocampal Cultures Following Excitotoxin Treatment

1997 • 50 citations

Potential Treatment of Alzheimer Disease Using Cholinergic Channel Activators (ChCAs) with Cognitive Enhancement, Anxiolytic-like, and Cytoprotective Properties

1995 • 43 citations

Conversion of the sodium channel activator aconitine into a potent α7‐selective nicotinic ligand

1995 • 43 citations

Specific down-regulation of the alpha-bungarotoxin binding component on chick autonomic neurons by ciliary neuronotrophic factor

1989 • 40 citations

Isolation, Characterization, and Use of Stem Cells from the CNS

1995 • 27 citations

Effect of dibutyryl cAMP on the enzymes of fatty acid synthesis and of glycogen metabolism

1970 • 15 citations

Characterization of nicotinic receptors in immortalized hippocampal neurons

1996 • 11 citations

Deafferentation removes calretinin immunopositive terminals, but does not induce degeneration of calbindin D‐28k and parvalbumin expressing neurons in the hippocampus of adult rats

1994 • 9 citations