Isolation, Characterization, and use of Stem Cells from the CNS

Generation of Neurons and Astrocytes from Isolated Cells of the Adult Mammalian Central Nervous System

1992 • 5,296 citations

CNS stem cells express a new class of intermediate filament protein

1990 • 3,138 citations

Long-Distance Neuronal Migration in the Adult Mammalian Brain

1994 • 2,291 citations

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

1983 • 2,009 citations

The Biochemical Basis of Neuropharmacology.

1974 • 1,911 citations

Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone

1993 • 1,799 citations

Cerebellar Cortex: Cytology and Organization

1974 • 1,705 citations

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: An immunocytological study in the central nervous system

1981 • 1,131 citations

Monoclonal antibody to a plasma membrane antigen of neurons.

1979 • 965 citations

Multipotent neural cell lines can engraft and participate in development of mouse cerebellum

1992 • 928 citations

Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside.

1982 • 842 citations

Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor ceil

1988 • 833 citations

Isolation of a stem cell for neurons and glia from the mammalian neural crest

1992 • 796 citations

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion.

1984 • 739 citations

Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain

1993 • 714 citations

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells.

1990 • 573 citations

De novo generation of neuronal cells from the adult mouse brain.

1992 • 535 citations

Two-stage expression of neurofilament polypeptides during rat neurogenesis with early establishment of adult phosphorylation patterns

1987 • 503 citations

Glial growth factor restricts mammalian neural crest stem cells to a glial fate

1994 • 496 citations

Identification of an adult-specific glial progenitor cell

1989 • 476 citations

Region-specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain

1991 • 474 citations

Proliferation, differentiation, and long-term culture of primary hippocampal neurons.

1993 • 461 citations

Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections

1988 • 429 citations

Postmitotic death is the fate of constitutively proliferating cells in the subependymal layer of the adult mouse brain

1992 • 393 citations

Cloning and growth of multipotential neural precursors: Requirements for proliferation and differentiation

1993 • 381 citations

Establishment and characterization of multipotent neural cell lines using retrovirus vector‐mediated oncogene transfer

1990 • 375 citations

Brain basic fibroblast growth factor stimulates the proliferation of rat neuronal precursor cells in vitro

1987 • 336 citations

Purified astrocytes promote the in vitro division of a bipotential glial progenitor cell.

1984 • 336 citations

Neurons switch from non-neuronal enolase to neuron-specific enolase during differentiation

1980 • 334 citations

Cell lines established by a temperature-sensitive simian virus 40 large-T-antigen gene are growth restricted at the nonpermissive temperature.

1989 • 318 citations

The generation of neurons and oligodendrocytes from a common precursor cell

1991 • 274 citations

Neurogenesis persists in the subependymal layer of the adult mouse brain

1993 • 262 citations

Fibroblast growth factor-mediated proliferation of central nervous system precursors depends on endogenous production of insulin-like growth factor I.

1991 • 245 citations

Characterization of potential precursor populations in the mouse olfactory epithelium using immunocytochemistry and autoradiography

1991 • 244 citations

Fos-IacZ transgenic mice: Mapping sites of gene induction in the central nervous system

1992 • 237 citations

Reversal of pathology in murine mucopolysaccharidosis type VII by somatic cell gene transfer

1992 • 221 citations

Neuroplasticity in the olfactory system: Differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B‐50/GAP43 and the olfactory marker protein

1990 • 197 citations

The expression and distribution of the microtubule-associated proteins tau and microtubule-associated protein 2 in hippocampal neurons in the rat in situ and in cell culture

1987 • 195 citations

Neurogenesis in the 3‐month‐old rat visual cortex

1981 • 193 citations

Increased life span and correction of metabolic defects in murine mucopolysaccharidosis type VII after syngeneic bone marrow transplantation

1991 • 186 citations

The development of the purkinje cells and of the cortical layers in the cerebellum of the albino rat

1911 • 169 citations

Plasticity of connections of the olfactory sensory neuron: Regeneration into the forebrain following bulbectomy in the neonatal mouse

1979 • 165 citations

Vitamin D-Dependent Calcium-Binding Protein in Rat Brain: Biochemical and Immunocytochemical Characterization*

1983 • 162 citations

Spinal cord neuroblasts proliferate in response to basic fibroblast growth factor

1994 • 151 citations

Origin of extraembryonic mesoderm in experimental animals: Relevance to chorionic mosaicism in humans

1993 • 133 citations

The use of cell lines in neurobiology

1990 • 128 citations

Membrane Depolarization Induces p140 ^trk and NGF Responsiveness, but Not p75 ^LNGFR , in MAH Cells

1992 • 120 citations

Grafting in the mammalian central nervous system

1993 • 114 citations

Coexistence of perinatal and adult forms of a glial progenitor cell during development of the rat optic nerve

1990 • 94 citations

Temporal relationship between the appearance of vimentin and neural tube development

1983 • 91 citations

Variable Morphological Differentiation of a Raphé-Derived Neuronal Cell Line Following Transplantation into the Adult Rat CNS

1993 • 91 citations

Immortalization of bipotential and plastic glio-neuronal precursor cells.

1990 • 69 citations

Thymidine Incorporation in the olfactory epihelium of mice: Early exponential response induced by olfactory neurectomy

1984 • 52 citations

The olfactory apparatus of the bandicoot (Isoodon macrourus): fine structure and presence of a septal olfactory organ.

1978 • 49 citations

Role of the c-myc and the N-myc proto-oncogenes in the immortalization of neural precursors

1989 • 47 citations

Co-expression of multiple neurotransmitter enzyme genes in normal and immortalized sympathoadrenal progenitor cells

1991 • 46 citations

Basic fibroblast growth factor upregulates steady-state levels of laminin B1 and B2 chain mRNA in cultured neuroepithelial cells

1991 • 35 citations

The postnatal development of the canine cerebellar cortex

1968 • 31 citations

V-myc immortalization of early rat neural crest cells yields a clonal cell line which generates both glial and adrenergic progenitor cells

1991 • 30 citations

In vitro proliferation and terminal differentiation of quail neural crest cells in a defined culture medium

1985 • 19 citations