Activation of α₇ nicotinic acetylcholine receptor promotes survival of spinal cord motoneurons

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Analysis of gene expression in single live neurons.

1992 • 944 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

1993 • 543 citations

The neurotrophic theory and naturally occurring motoneuron death

1989 • 397 citations

Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor.

1993 • 389 citations

Higher levels of nicotine in arterial than in venous blood after cigarette smoking

1993 • 374 citations

Fitting and Statistical Analysis of Single-Channel Records

1995 • 333 citations

Nicotinic receptors that bind α-bungarotoxin on neurons raise intracellular free ca2+

1992 • 263 citations

Neuronal acetylcholine receptors that bind α-bungarotoxin with high affinity function as ligand-gated ion channels

1994 • 254 citations

Neuromuscular blockade increases motoneurone survival during normal cell death in the chick embryo

1978 • 246 citations

Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.

1994 • 210 citations

The absence of significant postnatal motoneuron death in the brachial and lumbar spinal cord of the rat

1986 • 175 citations

Human alpha4beta2 neuronal nicotinic acetylcholine receptor in HEK 293 cells: A patch-clamp study.

1996 • 169 citations

Stimulus-induced coordinate changes in mRNA abundance in single postsynaptic hippocampal CA1 neurons

1992 • 159 citations

Postnatal development of neurons containing choline acetyltransferase in rat spinal cord: An immunocytochemical study

1984 • 155 citations

Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor

1992 • 154 citations

Human α4β2 Neuronal Nicotinic Acetylcholine Receptor in HEK 293 Cells: A Patch-Clamp Study

1996 • 154 citations

Barium permeability of neuronal nicotinic receptor alpha 7 expressed in Xenopus oocytes

1993 • 92 citations

The nicotinic blocking agents d-tubocurare and alpha-bungarotoxin save motoneurons from naturally occurring death in the absence of neuromuscular blockade

1995 • 78 citations

Activation of the recombinant human alpha 7 nicotinic acetylcholine receptor significantly raises intracellular free calcium.

1997 • 74 citations

Elevation of intracellular calcium levels in neurons by nicotinic acetylcholine receptors

1996 • 72 citations

Motoneurons deprived of trophic support in vitro require new gene expression to undergo programmed cell death

1994 • 68 citations

Brief-lifetime, fast-inactivating ion channels account for the α-bungarotoxin-sensitive nicotinic response in hippocampal neurons

1993 • 66 citations

Low-Noise Recording

1995 • 51 citations

Expression profiling of GABA_A receptor β-subunits in the rat retina

1994 • 48 citations

Chapter 7 Axonal outgrowth and pathfinding

1994 • 32 citations

Exogenously administered alpha-bungarotoxin binds to embryonic chick spinal cord: Implications for the toxin-induced arrest of naturally occurring motoneuron death

1993 • 25 citations