Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

1993 • 2,370 citations

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

1987 • 2,368 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

The murine and Drosophila homeobox gene complexes have common features of organization and expression

1989 • 1,021 citations

Nucleotide sequence and exact localization of the neomycin phosphotransferase gene from transposon Tn5

1982 • 936 citations

The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes.

1989 • 912 citations

Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5

1991 • 856 citations

Segmental patterns of neuronal development in the chick hindbrain

1989 • 840 citations

Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons

1988 • 739 citations

Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression

1991 • 698 citations

A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a selector gene

1993 • 631 citations

Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation

1989 • 612 citations

Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11

1995 • 587 citations

Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain

1989 • 566 citations

Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest

1993 • 556 citations

Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6

1992 • 537 citations

Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut

1995 • 531 citations

Sexually dimorphic sterility phenotypes in HoxalO-deficient mice

1995 • 516 citations

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

1989 • 511 citations

A distinct Hox code for the branchial region of the vertebrate head

1991 • 503 citations

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx

1995 • 493 citations

Vital dye analysis of cranial neural crest cell migration in the mouse embryo

1992 • 470 citations

Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity

1992 • 461 citations

Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs

1993 • 454 citations

Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain

1993 • 452 citations

Mice homozygous for a targeted disruption of the proto-oncogeneint-2have developmental defects in the tail and inner ear

1993 • 446 citations

The role of Hoxa-3 in mouse thymus and thyroid development

1995 • 421 citations

Two rhombomeres are altered in Hoxa-1 mutant mice

1993 • 391 citations

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1992 • 364 citations

Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments

1993 • 352 citations

Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.

1991 • 344 citations

Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain

1993 • 340 citations

Homeobox gene expression correlated with the bifurcation process of limb cartilage development

1991 • 317 citations

Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm

1990 • 300 citations

Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation.

1995 • 268 citations

Homeotic transformations and limb defects in Hox A11 mutant mice.

1993 • 260 citations

Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning

1996 • 259 citations

Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of hoxd-11

1994 • 253 citations

Advances in Anatomy, Embryology and Cell Biology

1982 • 248 citations

Expression of the mouse labial-Alike homeobox-containing genes, Hox 2.9 and Hox 1.6, during segmentation of the hindbrain

1991 • 239 citations

A mutational analysis of the 5′ HoxD genes: dissection of genetic interactions during limb development in the mouse

1996 • 229 citations

Compound mutants for the paralogous hoxa-4, hoxb-4, and hoxd-4 genes show more complete homeotic transformations and a dose-dependent increase in the number of vertebrae transformed.

1995 • 228 citations

Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds.

1995 • 205 citations

Development of the Cranial Nerve Ganglia and Related Nuclei in the Rat

1982 • 202 citations

Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene.

1993 • 183 citations

Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton

1996 • 154 citations

High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors.

1992 • 141 citations

The Hox-4.8 gene is localized at the 5′ extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development

1991 • 135 citations

Targeted Disruption ofhoxc-4Causes Esophageal Defects and Vertebral Transformations

1996 • 134 citations

Moebius syndrome.

1990 • 129 citations

Domains of cellular retinoic acid-binding protein I (CRABP I) expression in the hindbrain and neural crest of the mouse embryo

1992 • 118 citations

Targeted disruptions of the murine Hoxa-4 and Hoxa-6 genes result in homeotic transformations of components of the vertebral column

1994 • 116 citations

Expression and modification of Hox 2.1 protein in mouse embryos

1992 • 91 citations

Hoxc-9 mutant mice show anterior transformation of the vertebrae and malformation of the sternum and ribs

1995 • 78 citations

Quantitation and tissue localization of the cellular retinoic acid‐binding protein

1987 • 51 citations