Up-Regulation of Gene Related to Anergy in Lymphocytes Is Associated with Notch-Mediated Human T Cell Suppression

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells

2004 • 890 citations

The role of Notch in tumorigenesis: oncogene or tumour suppressor?

2003 • 786 citations

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

2004 • 512 citations

REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY

2005 • 434 citations

Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling

2004 • 306 citations

Delta1-Notch3 Interactions Bias the Functional Differentiation of Activated CD4+ T Cells

2003 • 289 citations

GRAIL

2003 • 280 citations

Notch signalling during peripheral T-cell activation and differentiation

2006 • 234 citations

E3 ubiquitin ligases as T cell anergy factors

2004 • 224 citations

Multiple niches for Notch in cancer: context is everything

2003 • 211 citations

T‐Cell Unresponsiveness in vivo and in vitro: Fine Specificity of Induction and Molecular Characterization of the Unresponsive State

1987 • 190 citations

Notch 1 Signaling Regulates Peripheral T Cell Activation

2004 • 159 citations

Notch signaling in development and disease

2003 • 142 citations

Expression of Activated Notch3 in Transgenic Mice Enhances Generation of T Regulatory Cells and Protects against Experimental Autoimmune Diabetes

2003 • 124 citations

Induction of Antigen-Specific Regulatory T Cells following Overexpression of a Notch Ligand by Human B Lymphocytes

2003 • 115 citations

Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells

2005 • 101 citations

Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell–dependent mechanism

2003 • 73 citations

Paradoxical inhibition of T-cell function in response to CTLA-4 blockade; heterogeneity within the human T-cell population

2000 • 72 citations

Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell–dependent mechanism

2003 • 68 citations

The Notch Regulator Numb Links the Notch and TCR Signaling Pathways

2005 • 53 citations

Small Interfering RNA-Mediated Knockdown of Notch Ligands in Primary CD4+ T Cells and Dendritic Cells Enhances Cytokine Production

2006 • 33 citations