Notch 1 Signaling Regulates Peripheral T Cell Activation

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1995 • 5,143 citations

CTLA-4 can function as a negative regulator of T cell activation

1994 • 2,107 citations

Induction by Antigen of Intrathymic Apoptosis of CD4 ⁺ CD8 ⁺ TCR ^lo Thymocytes in Vivo

1990 • 1,781 citations

Signalling downstream of activated mammalian Notch

1995 • 1,375 citations

Induction of T Cell Development from Hematopoietic Progenitor Cells by Delta-like-1 In Vitro

2002 • 1,095 citations

Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination

1999 • 956 citations

Functional gamma‐secretase inhibitors reduce beta‐amyloid peptide levels in brain

2001 • 876 citations

Presenilin is required for activity and nuclear access of Notch in Drosophila

1999 • 801 citations

Following a diabetogenic T cell from genesis through pathogenesis

1993 • 708 citations

Current Protocols in Immunology

2001 • 641 citations

An Activated Form of Notch Influences the Choice between CD4 and CD8 T Cell Lineages

1996 • 488 citations

Notch Activity Influences the αβ versus γδ T Cell Lineage Decision

1997 • 399 citations

Intercellular signals regulating pancreas development and function

2001 • 399 citations

Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system

1997 • 364 citations

Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody.

1990 • 360 citations

Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation

1998 • 328 citations

Immobilization of Notch ligand, Delta-1, is required for induction of Notch signaling

2000 • 309 citations

Presenilin-1 and -2 Are Molecular Targets for γ-Secretase Inhibitors

2000 • 300 citations

Delta1-Notch3 Interactions Bias the Functional Differentiation of Activated CD4+ T Cells

2003 • 289 citations

TCR-Mediated Notch Signaling Regulates Proliferation and IFN-γ Production in Peripheral T Cells

2003 • 228 citations

Notch Signaling Augments T Cell Responsiveness by Enhancing CD25 Expression

2003 • 218 citations

Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4+ T cells

2000 • 207 citations

Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch

1993 • 203 citations

An Invitation to T and More

2002 • 148 citations

Notch in vertebrates

1997 • 120 citations

Induction of Antigen-Specific Regulatory T Cells following Overexpression of a Notch Ligand by Human B Lymphocytes

2003 • 115 citations

Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell–dependent mechanism

2003 • 73 citations

Notch ligation by Delta1 inhibits peripheral immune responses to transplantation antigens by a CD8+ cell–dependent mechanism

2003 • 68 citations

Linked Suppression in Peripheral T Cell Tolerance to the House Dust Mite Derived Allergen Der p 1

1999 • 30 citations

Development and applications of surface-linked single chain antibodies against T-cell antigens

2001 • 29 citations