Myofibroblasts: Molecular crossdressers

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

1993 • 2,169 citations

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

1997 • 2,136 citations

MyoD or Myf-5 is required for the formation of skeletal muscle

1993 • 1,663 citations

Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction

1971 • 1,458 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

1995 • 1,154 citations

TRANSCRIPTIONAL CONTROL OF MUSCLE DEVELOPMENT BY MYOCYTE ENHANCER FACTOR-2 (MEF2) PROTEINS

1998 • 1,026 citations

Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD.

1989 • 984 citations

Myogenin gene disruption results in perinatal lethality because of severe muscle defect

1993 • 912 citations

Myofibroblasts. I. Paracrine cells important in health and disease

1999 • 908 citations

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

1991 • 874 citations

PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis

1996 • 867 citations

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

1995 • 817 citations

Identification of MRF4: a new member of the muscle regulatory factor gene family.

1989 • 779 citations

Inhibition of myocardial endothelin pathway improves long-term survival in heart failure

1996 • 630 citations

Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis.

1996 • 601 citations

Know Your Neighbors: Three Phenotypes in Null Mutants of the Myogenic bHLH Gene MRF4

1996 • 572 citations

Resistance to Apoptosis Conferred by Cdk Inhibitors During Myocyte Differentiation

1996 • 494 citations

Water transport revisited

1999 • 423 citations

Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors.

1996 • 420 citations

MyoD-Induced Expression of p21 Inhibits Cyclin-Dependent Kinase Activity upon Myocyte Terminal Differentiation

1995 • 416 citations

Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-β1 and endothelin-1 from fibroblasts

1998 • 406 citations

Immunocytochemical Detection of Desmin in Fat-Storing Cells (Ito Cells)

1984 • 393 citations

Paracrine PDGF-B/PDGF-Rβ signaling controls mesangial cell development in kidney glomeruli

1998 • 359 citations

Angiotensin II Stimulated Expression of Transforming Growth Factor-β1in Cardiac Fibroblasts and Myofibroblasts

1997 • 350 citations

The cellular pathogenesis of portal hypertension: Stellate cell contractility, endothelin, and nitric oxide

1997 • 334 citations

Cell cycle exit upon myogenic differentiation

1997 • 323 citations

The Myofibroblast

1998 • 291 citations

Inhibitory Function of p21 ^Cip1/WAF1 in Differentiation of Primary Mouse Keratinocytes Independent of Cell Cycle Control

1998 • 285 citations

Expression of the gene of the α-smooth muscle-actin isoform in rat liver and in rat fat-storing (ITO) cells

1990 • 283 citations

Id2 Specifically Alters Regulation of the Cell Cycle by Tumor Suppressor Proteins

1996 • 242 citations

Paired MyoD-binding sites regulate myosin light chain gene expression.

1991 • 216 citations

Deficiency in Rhabdomyosarcomas of a Factor Required for MyoD Activity and Myogenesis

1993 • 215 citations

Desmin in Muscle Formation and Maintenance: Knockouts and Consequences.

1997 • 213 citations

MyoD induces growth arrest independent of differentiation in normal and transformed cells.

1990 • 203 citations

Endothelin antagonism in experimental hepatic fibrosis. Implications for endothelin in the pathogenesis of wound healing.

1996 • 198 citations

Evidence for Distinct Signaling Properties and Biological Responses Induced by the PDGF Receptor α and β Subtypes

1999 • 197 citations

α-Smooth muscle actin is transiently expressed in embryonic rat cardiac and skeletal muscles

1988 • 183 citations

The Transcription Factor MEF2C-Null Mouse Exhibits Complex Vascular Malformations and Reduced Cardiac Expression of Angiopoietin 1 and VEGF

1999 • 180 citations

An E-box within the MHC IIB gene is bound by MyoD and is required for gene expression in fast muscle

1999 • 176 citations

Multiple Roles for the MyoD Basic Region in Transmission of Transcriptional Activation Signals and Interaction with MEF2

1998 • 147 citations

Specific Inhibitors of Platelet-Derived Growth Factor or Epidermal Growth Factor Receptor Tyrosine Kinase Reduce Pulmonary Fibrosis in Rats

1999 • 144 citations

Cadherins Promote Skeletal Muscle Differentiation in Three-dimensional Cultures

1997 • 125 citations

The basic helix-loop-helix transcription factor Mist1 functions as a transcriptional repressor of MyoD

1998 • 120 citations

Myosin light chain enhancer activates muscle-specific, developmentally regulated gene expression in transgenic mice.

1989 • 113 citations

Rb functions to inhibit apoptosis during myocyte differentiation.

1997 • 110 citations

MyoD induces retinoblastoma gene expression during myogenic differentiation.

1994 • 104 citations

An E box in the desmin promoter cooperates with the E box and MEF-2 sites of a distal enhancer to direct muscle-specific transcription.

1994 • 96 citations

Myocyte-specific enhancer binding factor 2C expression in human brain development

1994 • 89 citations

The detection of smooth muscle desmin-like protein in BHK21/C13 fibroblasts.

1979 • 85 citations

Sarcomeric Gene Expression and Contractility in Myofibroblasts

1997 • 79 citations

Homeodomain protein MHox and MADS protein myocyte enhancer-binding factor-2 converge on a common element in the muscle creatine kinase enhancer

1994 • 76 citations

Distinct Regulatory Elements Control Muscle-Specific, Fiber-Type-Selective, and Axially Graded Expression of a Myosin Light-Chain Gene in Transgenic Mice†

1996 • 63 citations

Macrophage and myofibroblast proliferation in remnant kidney: role of angiotensin II.

1997 • 56 citations

Macrophage and myofibroblast involvement in ischemic acute renal failure is attenuated by endothelin receptor antagonists

1999 • 54 citations

The transcription of MyoD1 and myogenin genes in thymic cells in vivo

1992 • 49 citations

Identification of Promoter Elements Involved in Cell-specific Regulation of Rat Smooth Muscle Myosin Heavy Chain Gene Transcription

1996 • 48 citations

Angiotensin II Type 1 Receptor Blockade Prevents Cardiac Remodeling in Bradykinin B ₂ Receptor Knockout Mice

2000 • 38 citations

Differential activation of the SMαA promoter in smooth vs. skeletal muscle cells by bHLH factors

1999 • 30 citations

Baby hamster kidney (BHK-21/C13) cells can express striated muscle type proteins

1991 • 29 citations

Metabolic Responses of Extracellular Matrix in Tissue Repair

1997 • 25 citations

Local Angiotensin II and Myocardial Fibrosis

1997 • 20 citations

A proximal promoter element in the hamster desmin upstream regulatory region is responsible for activation by myogenic determination factors.

1994 • 18 citations

Isolation and characterization of actin from cultured BHK cells

1987 • 17 citations

Expression of sarcomeric proteins and assembly of myofibrils in the putative myofibroblast cell line BHK-21/C13.

1998 • 12 citations

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