Paired MyoD-binding sites regulate myosin light chain gene expression.

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

1989 • 919 citations

A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.

1989 • 863 citations

MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer

1989 • 861 citations

MyoD1: A Nuclear Phosphoprotein Requiring a Myc Homology Region to Convert Fibroblasts to Myoblasts

1988 • 839 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Identification of MRF4: a new member of the muscle regulatory factor gene family.

1989 • 779 citations

A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes.

1989 • 605 citations

Positive autoregulation of the myogenic determination gene MyoD1

1989 • 492 citations

Alternative transcription and two modes of splicing result in two myosin light chains from one gene

1984 • 400 citations

Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene.

1989 • 326 citations

MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation.

1990 • 294 citations

Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization.

1990 • 278 citations

Fast skeletal muscle myosin light chains 1 and 3 are produced from a single gene by a combined process of differential RNA transcription and splicing.

1984 • 265 citations

Two adjacent MyoD1-binding sites regulate expression of the acetylcholine receptor α-subunit gene

1990 • 261 citations

A single locus in the mouse encodes both myosin light chains 1 and 3, a second locus corresponds to a related pseudogene

1984 • 256 citations

Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene.

1988 • 248 citations

A muscle-specific enhancer is located at the 3' end of the myosin light-chain 1/3 gene locus.

1988 • 212 citations

Transcriptional regulation of the muscle creatine kinase gene and regulated expression in transfected mouse myoblasts.

1986 • 173 citations

A New Myocyte-Specific Enhancer-Binding Factor That Recognizes a Conserved Element Associated with Multiple Muscle-Specific Genes

1989 • 154 citations

Myosin light chain enhancer activates muscle-specific, developmentally regulated gene expression in transgenic mice.

1989 • 113 citations

Optimizing the northern blot procedure.

1990 • 109 citations

Identification of a Myocyte Nuclear Factor That Binds to the Muscle-Specific Enhancer of the Mouse Muscle Creatine Kinase Gene

1989 • 101 citations

A highly conserved enhancer downstream of the human MLC1/3 locus is a target for multiple myogenic determination factors

1990 • 96 citations

Identification of Upstream and Intragenic Regulatory Elements That Confer Cell-Type-Restricted and Differentiation-Specific Expression on the Muscle Creatine Kinase Gene

1988 • 86 citations

Promoter upstream elements of the chicken cardiac myosin light-chain 2-A gene interact with trans-acting regulatory factors for muscle-specific transcription.

1989 • 76 citations

A cell type-specific enhancer drives expression of the chick muscle acetylcholine receptor α-subunit gene

1988 • 71 citations

Transcriptional Regulation of the Muscle Creatine Kinase Gene and Regulated Expression in Transfected Mouse Myoblasts

1986 • 67 citations

Expression of the acetylcholine receptor delta-subunit gene in differentiating chick muscle cells is activated by an element that contains two 16 bp copies of a segment of the alpha-subunit enhancer.

1990 • 51 citations

Promoter Upstream Elements of the Chicken Cardiac Myosin LightChain 2-A Gene Interact with trans-Ading Regulatory Factors for Muscle-Specific Transcription

1989 • 15 citations