Insulin-Resistant Diabetes Due to a Point Mutation That Prevents Insulin Proreceptor Processing

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.

1986 • 1,866 citations

The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

1985 • 1,485 citations

The Syndromes of Insulin Resistance and Acanthosis Nigricans

1976 • 1,086 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Nucleotide Sequence of Yellow Fever Virus: Implications for Flavivirus Gene Expression and Evolution

1985 • 947 citations

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

1985 • 706 citations

The Molecular Mechanism of Insulin Action

1985 • 424 citations

Continuous Lymphoid Cell Lines with Characteristics of B Cells (Bone-Marrow-Derived), Lacking the Epstein-Barr Virus Genome and Derived from Three Human Lymphomas

1974 • 336 citations

The Nature and Regulation of the Insulin Receptor: Structure and Function

1985 • 318 citations

Influenza virus a pathogenicity: The pivotal role of hemagglutinin

1987 • 276 citations

Biosynthesis and glycosylation of the insulin receptor. Evidence for a single polypeptide precursor of the two major subunits.

1983 • 216 citations

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor

1986 • 203 citations

High-level expression of human insulin receptor cDNA in mouse NIH 3T3 cells.

1987 • 151 citations

Familial Hypertrophy of Pineal Body, Hyperplasia of Adrenal Cortex and Diabetes Mellitus: Report of 3 Cases

1956 • 124 citations

Cloning of a drosophila cDNA encoding a polypeptide similar to the human insulin receptor precursor

1986 • 73 citations

Biologic and Clinical Importance of Proinsulin

1984 • 71 citations

Primary Structure and Processing of gag and env Gene Products of Human T-Cell Leukemia Viruses HTLV-ICR and HTLV-IATK

1985 • 56 citations

Decreased Insulin Binding to Cultured Cells from a Patient with the Rabson-Mendenhall Syndrome: Dichotomy between Studies with Cultured Lymphocytes and Cultured Fibroblasts*

1983 • 55 citations

Partial N-terminal amino acid sequences of three nonstructural proteins of two flaviviruses

1986 • 54 citations

Receptor defects in patients with extreme insulin resistance

1985 • 43 citations

Defective processing of insulin-receptor precursor in cultured lymphocytes from a patient with extreme insulin resistance.

1988 • 27 citations