Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Rapid similarity searches of nucleic acid and protein data banks.

1983 • 1,577 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Epidermal Growth Factor and a New Derivative

1972 • 1,225 citations

Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

1980 • 1,184 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Growth factors: Mechanism of action and relation to oncogenes

1984 • 885 citations

The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins

1985 • 845 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

1983 • 721 citations

Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells

1981 • 669 citations

Vinculin: A cytoskeletal target of the transforming protein of rous sarcoma virus

1981 • 591 citations

A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells

1985 • 456 citations

Expression of the c- fos Gene and of an fos -Related Gene Is Stimulated by Platelet-Derived Growth Factor

1984 • 445 citations

Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts.

1985 • 344 citations

c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors

1985 • 300 citations

New versatile cloning and sequencing vectors based on bacteriophage M13

1983 • 263 citations

Stimulation and inhibition of growth by EGF in different A431 cell clones is accompanied by the rapid induction of c-fos and c-myc proto-oncogenes.

1985 • 257 citations

Is actin a transcription initiation factor for RNA polymerase B?

1984 • 234 citations

Split-gene evolution: Exon shuffling and intron insertion in serine protease genes

1985 • 217 citations

Vinculin, a cytoskeletal substrate of protein kinase C.

1983 • 215 citations

Specific stimulation of actin gene transcription by epidermal growth factor and cycloheximide.

1984 • 215 citations

Temperature-sensitive growth regulation in one type of transformed rat cells induced by the tsa mutant of polyoma virus

1977 • 211 citations

The ras oncogene product p21 is not a regulatory component of adenylate cyclase

1985 • 210 citations

Type beta transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval.

1985 • 191 citations

Cassette of Eight Exons Shared by Genes for LDL Receptor and EGF Precursor

1985 • 185 citations

Phospholipid Turnover in Hormone Action

1984 • 178 citations

The cytoskeleton in cancer cells

1985 • 170 citations

Making sense out of LINES: long interspersed repeat sequences in mammalian genomes

1985 • 162 citations

Structural analysis of the prolactin gene suggests a separate origin for its 5′ end

1982 • 159 citations

Transcripts regulated during normal embryonic development and oncogenic transformation share a repetitive element

1983 • 146 citations

Epidermal growth factor induces redistribution of actin and α-actinin in human epidermal carcinoma cells

1981 • 139 citations

Expression of enhanced levels of small RNA polymerase III transcripts encoded by the B2 repeats in simian virus 40-transformed mouse cells

1985 • 139 citations

Tumor promoters induce changes in the chick embryo fibroblast cytoskeleton

1979 • 138 citations

Epidermal growth factor or serum stimulation of rat fibroblasts induces an elevation in mRNA levels for lactate dehydrogenase and other glycolytic enzymes

1985 • 137 citations

State of the viral DNA in rat cells transformed by polyoma virus. I. Virus rescue and the presence of nonintergrated viral DNA molecules

1976 • 127 citations

Transforming growth factor-beta modulates the high-affinity receptors for epidermal growth factor and transforming growth factor-alpha.

1985 • 111 citations

Properties of carcinogen altered mouse epidermal cells resistant to calcium-induced terminal differentiation

1983 • 109 citations

Complete amino acid sequence of human hemopexin, the heme-binding protein of serum.

1985 • 102 citations

Isolation by molecular cloning of a fragment of the split ovalbumin gene

1978 • 78 citations

Polyadenylylated RNA complementary to a mouse retrovirus-like multigene family is rapidly and specifically induced by epidermal growth factor stimulation of quiescent cells.

1982 • 77 citations

Rapidsimilarity searches ofnucleic acidandprotein databanks

1983 • 72 citations

Growth factors and oncogenes

1985 • 55 citations

Long interspersed repeated DNA (LINE) causes polymorphism at the rat insulin 1 locus.

1985 • 44 citations

Epidermal growth factor and epidermal growth factor receptor-dependent phosphorylation of a Mr = 34,000 protein substrate for pp60src.

1983 • 36 citations

Regulation of the Transcript for a Lysosomal Protein: Evidence for a Gene Program Modified by Platelet-Derived Growth Factor

1985 • 36 citations

Mechanism of synergistic induction of DNA synthesis by epidermal growth factor and tumor promoters

1981 • 23 citations

Cloning of sequences expressed specifically in tumors of rat.

1983 • 22 citations

Regulation of the transcript for a lysosomal protein: evidence for a gene program modified by platelet-derived growth factor.

1985 • 20 citations

Effects of the tumor promoter TPA on the induction of DNA synthesis in normal and RSV‐transformed rat fibroblasts

1979 • 8 citations

Ecology as a molecular science

1978 • 3 citations